Please what drugs can i use to treat duodenal ulcer?

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There are three main types of medicines that can be used: 1) medicines that reduce the amount of acid produced, 2) medicines that protect the lining of the stomach and intestines, and 3) medicines that destroy the bacterium, H. pylori.
Medicines that reduce acid production are broken down into two categories.  Generally, with these medicines, duodenal ulcers heal within 4-6 weeks and gastric ulcers heal within 6-8 weeks.

1) Proton pump inhibitors -- Omeprazole and Lansoprazole are the most commonly used.  Basically, they very effectively reduce acid production by the stomach.  They are more potent than H2 receptor blockers but they are usually only used for short-term therapy.  They can help cure up to 80-90% of ulcers.  These medicines are usually taken 30 minutes before a meal.  They help to relieve symptoms and allow healing to take place faster than H2 blockers, but the overall cure rate for ulcers is not much different between the two groups.
2) H2 receptor blockers -- Cimetidine, Ranitidine, Famotidine, and Nizatidine are the 4 most commonly used medicines in this category.  These medicines also reduce acid production and they can be used for longer periods of time.  They are not as potent as the proton pump inhibitors, but they can be just as effective at curing ulcers.  They also can cure about 80-90% of ulcers.  Ulcer symptoms usually get better within about 2 weeks, but treatment is usually continued for 6-8 weeks.

Certain medicines are available that basically protect and preserve the lining of the stomach and duodenum.  These include:

1) Sucralfate -- this is a medicine that basically coats ulcers and forms a protective layer.  It is very good at treating duodenal ulcers.  It is not as good for treatment of gastric ulcers.
2) Bismuth -- this is a medicine that causes increased production of the substances that normally protect the stomach and intestines.  It also helps destroy H. pylori.
3) Misoprostol -- this is a medicine that increases the production of the substances that normally protect the stomach and intestines.  It is not as effective as the other medicines in treating an active ulcer.  It is used mainly to help prevent the formation of ulcers in people who are on long-term treatment with NSAIDs.
4) Antacids -- these are available over-the-counter.  These medicines help protect the wall of the stomach and intestines.  They do not reduce the formation of acid.  They are no longer used as initial treatment for ulcers because more effective medicines are available.  However, they do work very quickly and can be use to rapidly control symptoms.

Treatment depends on the cause of the ulcer.
For ulcers caused by H. pylori, there are several treatment options.

1) Metronidazole (500 mg twice a day) and clarithromycin (500 mg twice a day) and a proton pump inhibitor (such as omeprazole 20 mg twice a day) for 14 days.
2) Amoxicillin (1 gram twice a day) and clarithromycin (500 mg twice a day) and a proton pump inhibitor (such as omeprazole 20 mg twice a day) for 14 days.
3) Amoxicillin (1 gram twice a day) and metronidazole (500 mg twice a day) and a proton pump inhibitor (such as omeprazole 20 mg twice a day) for 14 days.
4) Bismuth subsalicylate (2 tablets 4 times a day) and tetracycline (500 mg 4 times a day) and either metronidazole (250 mg 4 times a day) or clarithromycin (500 mg 3 times a day) for 14 days.  Some are now recommending using ranitidine along with this regimen.
5) After the person has completed one of the above regimens, they need to be continued on a proton pump inhibitor, an H2 antagonist, or sucralfate for an additional 4-6 weeks.  This will help allow the ulcer to heal completely.
6) This course of therapy should destroy the bacterium in more than 85% of people.
7) Newer combinations are constantly being tested.  Therefore, it is best to discuss treatment options with your doctor.
8 ) There are increasing reports of H. pylori being resistant to metronidazole.  Therefore, in areas where there is a lot of resistance to this antibiotic, the other treatment options are being used first.
9) In the past, most people with ulcers used to be continued on some sort of ulcer treatment for very long periods of time.  However, now that we have found out that many of these ulcers are due to an infection, most people no longer need prolonged anti-ulcer treatment if their infection is cured.  Therefore, only those who have recurrent ulcers, those in whom the infection could not be cured, and people with H. pylori infections who keep getting ulcers even though the infection was treated will need to be on long-term anti-ulcer treatment.
10) If the person is treated for H. pylori and the ulcer does not come back, no further evaluation or treatment is needed.  If the ulcer does come back, then they need testing to see if the H. pylori has truly been destroyed.

For ulcers caused by the frequent use of NSAID drugs (aspirin, ibuprofen, naproxen etc), treatment is a little different.

1) The first step is to stop using the NSAIDs.
2) Proton pump inhibitors (such as omeprazole, lansoprazole) should be started as soon as possible.  These are the most effective medicines.
3) You can also use H2 receptor antagonists or sucralfate, but these are not as effective.
4) If the person is on NSAIDs but tests also show the presence of H. pylori, then the best option is to stop the NSAIDs but also to go ahead and treat the H. pylori infection.
5) In people with ulcers, NSAIDs can be continued along with one of the above medicines if there is absolutely no other alternative.  However, healing of the ulcer will be delayed.

-Recurrent ulcers or ulcers that do not heal with normal treatments are fairly rare these days.  If this is truly the case, then other diagnoses must be considered.  The most common cause of ulcers not healing is because people do not take all the medicines as prescribed by the doctor or they resume use of NSAIDs.  Another common cause is H. pylori infections that are not adequately treated.
-Another cause is a missed cancer, especially with stomach ulcers that do not heal despite adequate therapy.  Therefore, all gastric ulcers need to be followed by repeat endoscopy to confirm that they have healed.  If they have not, then repeat biopsies should be done after 2-3 months of treatment.  Repeat endoscopies should be done periodically until the ulcer has completely healed.
-A much rarer cause of non-healing or recurrent ulcers is Zollinger-Ellison Syndrome.  Therefore, all people with continued ulcers should be checked for this condition.
-If all else fails and the person continues to have recurrent ulcers, then he or she may need surgery.  This is the last treatment option that should only be considered after all other options are exhausted.

To heal an ulcer you must kill the organism eating the tissue.

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Duodenal Ulcer: patients are usually skinny, lost weight, eating tends to make it worse.

Gastric Ulcer: usually FAT individuals, eating relieves the pain.

Hiv Patients: they usually have them. Could be due to corrosive effect of ARV. Can also be due to weak immune system and gastric erosion + infection of stomach lining.

Pain Relief(analgesic)drugs (NSAIDS)
Ibuprofen, cataflam, feldene, indomethacin etc used on a long term basis for chronic pain can lead to ulcer, nasty gastric ulcer.

Effect of peptic Ulcer:

Pain, loss of enjoyment of life, financial drain because of treatment rather than CURE drugs.

ANAEMIA from blood loss

AMENORRhOEA and scanty menses in female because of blood loss.

Don't TREAT your ulcer KILL and CURE it.

Get d CURE only N7000 for a 3 time dose cures you For Good !

Send mail : ulcerkill@mmmmail.com