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Intense physical activity that cause breathlessness creates a chemical release in the body. This releases compounds called catecholamines and epinephrine suppress the growth of tumour cells.

Exercise training and epinephrine did not completely prevent tumor formation, but induced reduction.
Exercise training can not replace anti-cancer therapy, but could be an effective supportive strategy and improves cancer treatment.

Researchers used experimental mice implanted with human breast cancer tumors as well as tumor cells in test tubes to investigate how serum samples from healthy women and breast cancer patients before and after exercise affect the development of the breast tumor cells, and the mechanism involved.

They discovered that serum samples taken after exercise reduced the ability of tumor cells to grow in test tubes or in mice. Less than half of mice with tumors steeped in post-exercise serum developed tumors, compared with 90 percent of mice with tumors not exposed to post-exercise serum.

The researchers traced the anti-tumor activity to a rise in epinephrine and norepinephrine that occurs with moderately intense exercise. Studies have shown that regular fitness can reduce risk of breast cancer and reoccurrence in those who already have it.
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