A synthetic gene network serves as an early warning for cancer growth, common types of cancer are prostate, lung, colon and breast cancer. Cancers develop when the level of calcium in the blood is elevated due to the developing tumour.

The early warning system comprises a genetic network that biotechnologists integrate into human body cells, which in turn are inserted into an implant. This encapsulated gene network is then implanted under the skin where it constantly monitors the blood calcium level.

When the calcium level exceeds a particular threshold value over a longer period of time, a signal cascade is triggered that initiates production of the body’s tanning pigment melanin in the genetically modified cells. The skin then forms a brown mole.

The mole appears long before the cancer becomes detectable through conventional diagnosis. The researchers used calcium as the indicator of the development of the four types of cancer, as it is regulated strongly in the body.

Bones serve as a buffer that can balance out concentration differences. However, when too much calcium is detected in the blood, this may serve as a sign for one of the four cancers. Moles developed when the calcium concentration reached a high level.
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