|
igodo
|
Could anyone give an answer to this?
|
|
|
|
|
|
doubletree (f)
|
The chances of having children with sickle cell disease is the same as when AS and AS have kids
1 in 4 chance of SC-sickle cell disease but may not be as severe as SS( but they are still sickle cell disease sufferers)
1 in 4 chance of AC
1 in 4 chance of AS
1 in 4 chance of AA-normal genotype
Bottom line is they risk having sicklecell children. just like AS/AS couples
|
|
|
|
|
|
Carlosein (m)
|
sorry, what is Ac genotype?
never heard of it before.
|
|
|
|
|
|
ifyalways (f)
|
sorry, what is Ac genotype?
never heard of it before.
bros i was wondering too. perharps its a typo.  |
|
|
|
|
|
doubletree (f)
|
Haemoglobin C exists it's not a typo.
It's another haemoglobin variant which in combination with Haemoglobin S results in sickle cell disease.
It's not as common as haemoglobin S
AC is a healthy carrier of Haemoglobin C
@poster why not post this in the health forum,you'll get more responses there.
|
|
|
|
|
|
debo25 (m)
|
my friend .this issue is deciding on which is best out of joy and sadness.although getting ababy of ss from parent of as and aa is achace but when the chance occur it is the beggining of calamity.
|
|
|
|
|
|
Carlosein (m)
|
Haemoglobin C exists it's not a typo.
It's another haemoglobin variant which in combination with Haemoglobin S results in sickle cell disease.
It's not as common as haemoglobin S
AC is a healthy carrier of Haemoglobin C
CC is not compatible with life.
@poster why not post this in the health forum,you'll get more responses there.
thanks for clearing things up doubletree, but can you put up a link where we can get more info on this rare haemoglobin variant please. |
|
|
|
|
|
Carlosein (m)
|
my friend .this issue is deciding on which is best out of joy and sadness.although getting ababy of ss from parent of as and aa is achace but when the chance occur it is the beggining of calamity.
debo25, i think you mean parents who are as and as because i don't think you can get offsprings who are ss from parents who are as and aa. |
|
|
|
|
|
doubletree (f)
|
@carlosein my information is from medical books but i found the info below on the uk sickle cell society website What are haemoglobin SC disease (Hb SC) and Sickle Beta-Thalassaemia (Hb S-Thal)?
These conditions occur when someone inherits sickle haemoglobin (Hb S) from one of their parents and either haemoglobin C or Beta-Thalassaemia from the other parent. The symptoms of these two conditions are often similar to, but usually less severe than, those of sickle cell anaemia. People with Sickle Cell Anaemia, Sickle Beta -Thalassaemia and SC disease can have problems with sight, although this retinopathy is more likely to occur in Hb SC individualshttp://www.sicklecellsociety.org/education/healthpr.htm#anchor209100 |
|
|
|
|
|
otokx (m)
|
So genotype AC exists; am just hearing it for the first time.
|
|
|
|
|
|
AkoEja
|
There are many haemoglobin types. Hb A, C , S, thalasaemia, etc.
A person with sickle cell disease can have genotype SS, SC or even CC.
SS suffers more than SC, and SC suffers more than CC, but they all have sicke cell disease.
If somebody has sickle cell trait(he/she is a carrier), he can be AC, or AS.
If two carriers marry, and want to avoid having a baby with sickle cell disease, the baby in the womb can be tested at 11-12 weeks of pregnancy or at 18 weeks of pregnancy, and if the baby is found to be a sickle cell sufferer, the couple can opt to terminate the pregnancy(this is legal in the UK and America, but not so in Nigeria, though its legal to do the test in Nigeria)
|
|
|
|
|
|
Godalone (m)
|
A man with AC genotype cannot marry a woman with AS genotype,it is very risky.A friend of mine quit a relationship of 3 years after dicovering that the guy has AC genotype while she is AS.Although it took the help of a doctor before the duo got separated,and they both see reasons why they cannot marry each other.
|
|
|
|
|
|
AkoEja
|
You say it as if its illegal to marry. they can marry but there is a risk of having a child with sickle cell disease or they can opt for prenatal diagnosis (if they have money) and only keep embryos without sicke cell disease
|
|
|
|
|
|
Ajebota (f)
|
SC though not as bad as SS is till serious, don't put your child through it! They would still get painful crises every so often.
|
|
|
|
|
|
AkoEja
|
Ajebota is right, SC sickler can be quite serious too
|
|
|
|
|
|
yinkuso08
|
AS genotypes bearing children is not advisable. We just buried a family friend's daughter who was 4yrs old last Thursday. 3 of my high school friends also died of this Sickle cell disease. Several people go into marriage without finding out blood types. I am happy that this is finally been addressed openly in Nigeria to the extent that a Yoruba movie was produced for this issue to teach the society. Some people follow the rule of 1 out of 4 with SS and would not mind risking it BUT in so many cases like that of our family friend, they only have 2 children and unfortunatly, both are SS. I know it is tough to seperate when one is in love, but please do not let the love overshadow your future. Not only will your child suffer from endless pain, the parents will also suffer numerous days and nights of crisis and the fear of the unknown. Nothing is as tough as having to bury a child. There is another couple I know who are both AS and have 4 boys with AS genotypes. The wife has terminated 10 pregnancies between each child because they went through the blood test everytime she was 10 weeks pregnant. If the baby was SS, they would terminate. Can you imagine how they must have felt everytime she had to go through that stage? It is avoidable so please be warned and Open Your Eyes, All the best.  |
|
|
|
|
|
![Nairaland [Nigerian Forum] Home](http://www.nairaland.com/Themes/default/images/english/home.gif)
Author
