Brooke hasn't aged in the conventional sense. Dr. Richard Walker of the University of South Florida College of Medicine, in Tampa, says Brooke's body is not developing as a coordinated unit, but as independent parts that are out of sync. She has never been diagnosed with any known genetic syndrome or chromosomal abnormality that would help explain why.
In a recent paper for the journal "Mechanisms of Ageing and Development," Walker and his co-authors, who include Pakula and All Children's Hospital (St. Petersburg, Fla.) geneticist Maxine Sutcliffe chronicled a baffling range of inconsistencies in Brooke's aging process. She still has baby teeth at 16, for instance. And her bone age is estimated to be more like 10 years old.
"There've been very minimal changes in Brooke's brain," Walker said. "Various parts of her body, rather than all being at the same stage, seem to be disconnected."
Brooke's mother, Melanie Greenberg, 48, sees a different picture. "She loves to shop," Greenberg said. "Just like a woman."
Brooke rides in a stroller while her mom shops for clothes in the infant sections of department stores near their home in a Baltimore suburb. That Brooke is in her mid-teens is so mind-boggling that if another mother with a toddler asks Greenberg how old Brooke is, she usually doesn't try to explain.
"My system always has been to turn years into months," Greenberg said. "So, if someone asked today, I might say, she's 16 months old
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