DR-TB
A patient is considered to be a drug resistant tuberculosis case if only there is a laboratory confirmation of resistance to one or more anti-tuberculosis drugs.



CLASSIFICATION OF TUBERCULOSIS BASED ON DRUG RESISTANCE
TB cases are classified in categories based on drug susceptibility testing in clinical isolates confirmed to be MYCOBACTERIUM TUBERCULOSIS.
1. MULTIDRUG-RESISTANCE(MDR): Refers to a DR-TB case whose resistance pattern to clinical isolates is to at least both isoniazid and rifampicin.
2. EXTENSIVE DRUG RESISTANCE (XDR) :refers to a DR-TB whose resistance pattern to clinical isolates is to any fluoroquinolone and at least one of three second-line injectable drugs(Capreomycin, Kanamycin and Amikacin) in addition to multidrug resistance.



LABORATORY TEST FOR DR-TB CASES
the following test should be carried out before a patient can be confirmed as a DR-TB patient
1. Genexpert/MTB RIF test (this is majorly used to detect DR-TB before samples are being sent for culture)
2. Culture




IDENTIFYING PRESUMPTIVE DR-TB CASES
Any patient who falls under these categories should be sent for Genexpert test to ascertain whether they are DR-TB patient or not.
1. All known symptomatic contacts of a confirmed DR-TB case.
2. All TB cases with AFB positive result after smear is repeated at the end of month three(3) of Regimen 1 treatment.
3. All previously treated DS-TB cases (Relapse, Treatment after failure to Regime 1, Treatment after loss to follow up, and other previously treated patients).
4. All patients with smear negative AFB result who still show symptoms of TB after 1 week administration of broad spectrum antibiotics.
5. All people living with HIV (PLHIV) with TB.
6. All health care staff with TB symptoms.
7. All children with TB symptoms.
8. Extra-pulmonary TB.

spread the word today, enlighten people within you community about this deadly disease.
STOP TUBERCULOSIS IN YOUR LIFE TIME.


www.tbfacts.org/drug-resistant-tb/