Lagusta:


Someone that doesn't know that thalassemia is a form of hemoglobinopathy does not deserve the medical degree abeg.....

My guy don't say that. U should go to his school and contend his degree, we can't know it all. Among the top 3 causes of death in a research done at John-Hopkins last year was found to be doctors errors, those doctors also don't deserve medical degrees?

Meanwhile, A lady who has 2 previous children and is rhesus negative gave birth recently, a direct coombs test and blood group was done for the new baby and the child was rhesus negative, I was happy for the child, question is would the woman need rhogam?, bearing the fact that the blood group of the other children are not known?, and they are not present to take their blood group.

Lastly hemoglobinopathies and thalassemias are actually different. and are on different topic. Not all thalasemias are hemoglobinopathies. Do ur research.

Lagusta:
The hemoglobinopathies encompass all genetic diseases of hemoglobin. They fall into two main groups: thalassemia syndromes and structural hemoglobin variants (abnormal hemoglobins). α- and β-thalassemia are the main types of thalassemia; the main structural hemoglobin variants are HbS, HbE and HbC. There are many subtypes and combined types in each group. The highly variable clinical manifestations of the hemoglobinopathies range from mild hypochromic anemia to moderate hematological disease to severe, lifelong, transfusion-dependent anemia with multiorgan involvement. Stem-cell transplantation is the preferred treatment for the severe forms of thalassemia. Supportive, rather than curative, treatment consists of periodic blood transfusions for life, combined with iron chelation. Drugs to treat the symptoms of sickle-cell disease include analgesics, antibiotics, ACE inhibitors and hydroxyurea. Blood transfusions should be given only when strictly indicated. More than 90% of patients currently survive into adulthood. Optimally treated patients have a projected life span of 50 to 60 years.

Source:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163784/

The guy read wikipedia, when he knows wikipedia is the worst reference any doctor would go to.....

Nigerian doctors..... Na wa ooo

Hehehe is that what you were taught in school? Is that all you could give? Wikipedia?...i thought you would give us stuff from Google scholar! Nice try

sgtponzihater1:


My guy don't say that. U should go to his school and contend his degree, we can't know it all. Among the top 3 causes of death in a research done at John-Hopkins last year was found to be doctors errors, those doctors also don't deserve medical degrees?

Meanwhile, A lady who has 2 previous children and is rhesus negative gave birth recently, a direct coombs test and blood group was done for the new baby and the child was rhesus negative, I was happy for the child, question is would the woman need rhogam?, bearing the fact that the blood group of the other children are not known?, and they are not present to take their blood group.

Hope the guy will understand this level you've brought him to... Lol. Moreover, no patient has ever lost his/her life under my care and I pray non will. Its God

escodotman:
Hehehe is that what you were taught in school? Is that all you could give? Wikipedia?...i thought you would give us stuff from Google scholar! Nice try

You are very stupid!!!

Is this a wikipedia source??

Did u even read my post!!!

Oh God how did I end up with this dimwit!!!!

escodotman:
Hope the guy will understand this level you've brought him to... Lol

I hope so too. Thalasemias, strictly speaking are not hemoglobinopathies, though some thalassemias can be, since hemoglobinopathies is really alteration in structure, while the other deal with production. There however is no need to query anyone's qualification, if u feel u know better simply explain professionally.

Lagusta:


You are very stupid!!!

Is this a wikipedia source??

Did u even read my post!!!

Oh God how did I end up with this dimwit!!!!

Hahahahaha e don pain am. He has resorted to abuse. And you call yourself a doctor?? Have you ever managed a psychiatric patient? If so, you must be beating a hell outta them with your temper!!! Hiann!!!

sgtponzihater1:


My guy don't say that. U should go to his school and contend his degree, we can't know it all. Among the top 3 causes of death in a research done at John-Hopkins last year was found to be doctors errors, those doctors also don't deserve medical degrees?

Meanwhile, A lady who has 2 previous children and is rhesus negative gave birth recently, a direct coombs test and blood group was done for the new baby and the child was rhesus negative, I was happy for the child, question is would the woman need rhogam?, bearing the fact that the blood group of the other children are not known?, and they are not present to take their blood group.

Lastly hemoglobinopathies and thalassemias are actually different. and are on different topic. Not all thalasemias are hemoglobinopathies. Do ur research.

No one is saying they are the same, what I am saying (and pointing out clearly) is that some thalassemias are a type of hemoglobinopathy, simple....

I have given you all sources and references... And please not from wikipedia.... Read up and let's move on abeg.....

sgtponzihater1:


I hope so too. Thalasemias, strictly speaking are not hemoglobinopathies, though some thalassemias can be, since hemoglobinopathies is really alteration in structure, while the other deal with production. There however is no need to query anyone's qualification, if u feel u know better simply explain professionally.

Bros my hats off to you. Thumbs up too. But brb, I gotta bath now.

sgtponzihater1:


I hope so too. Thalasemias, strictly speaking are not hemoglobinopathies, though some thalassemias can be, since hemoglobinopathies is really alteration in structure, while the other deal with production. There however is no need to query anyone's qualification, if u feel u know better simply explain professionally.

At least you speak more professionally jare.....

I believe we are saying the same thing, truly not all thalassemias are hemoglobinopathies but those types are very rare and incompatible with life..... We all know that....

Let's talk about common stuff...

Once again, thanks for your mature approach

escodotman:
Hahahahaha e don pain am. He has resorted to abuse. And you call yourself a doctor?? Have you ever managed a psychiatric patient? If so, you must be beating a hell outta them with your temper!!! Hiann!!!

I'm sorry for the outburst.....

Next time read my post before concluding....

Thanks

sgtponzihater1:


My guy don't say that. U should go to his school and contend his degree, we can't know it all. Among the top 3 causes of death in a research done at John-Hopkins last year was found to be doctors errors, those doctors also don't deserve medical degrees?

Meanwhile, A lady who has 2 previous children and is rhesus negative gave birth recently, a direct coombs test and blood group was done for the new baby and the child was rhesus negative, I was happy for the child, question is would the woman need rhogam?, bearing the fact that the blood group of the other children are not known?, and they are not present to take their blood group.

Lastly hemoglobinopathies and thalassemias are actually different. and are on different topic. Not all thalasemias are hemoglobinopathies. Do ur research.

To give my contribution on this question, I think the woman should be given rhogam if the the father of the newborn baby is Rhesus positive. This will protect the susbsquent pregnancies from the HDNB. (haemolytic disease of the new born). Off the bathroom

Lagusta:

I'm sorry for the outburst.....
Next time read my post before concluding....
Thanks

No probs bro. One love

escodotman:
To give my contribution on this question, I think the woman should be given rhogam if the the father of the newborn baby is Rhesus positive. This will protect the susbsquent pregnancies from the HDNB. (haemolytic disease of the new born). Off the bathroom

I need some other contributions on this, this lady have had 2 previous babies for 2 previous men, rhesus negative, but doesn't know the blood group of the other men or the other babies, she gave birth recently, it was actually a twin pregnancy, while the leading twin survived, the second twin couldn't make it due to a difficult labour. I advised them for rhogam, since here previous babies might have been rhesus positive, the MO and matron however said they have been in practice over 20 years and the woman doesn't need it.

sgtponzihater1:


I need some other contributions on this, this lady have had 2 previous babies for 2 previous men, rhesus negative, but doesn't know the blood group of the other men or the other babies, she gave birth recently, it was actually a twin pregnancy, while the leading twin survived, the second twin couldn't make it due to a difficult labour. I advised them for rhogam, since here previous babies might have been rhesus positive, the MO and matron however said they have been in practice over 20 years and the woman doesn't need it.

I get your question clearly now. The previous 2 babies' blood groups weren't known, neither were the blood group of their fathers. So the woman has another baby now who is Rhesus neg with the mother.

Now, I also agree with them that the woman doesnt need Rhogam. The baby she just had is rhesus neg and defintely it means the father is also rhesus neg, so there's no need for Rhogam because subsequent pregancies (through the current husband) are not in danger of maternal-fetal red blood cell incompatibilty since both father and mother belong to thesame Rhesus blood group. About the previous 2 babies, the most likely scenerio is that both babies and their fathers are also Rhesus negative, like the mother and thats why the twin didnt suffer any intra-uterine haemolysis and its complications. You know the essence of the Rheso-gamma immunoglobulin is to ''mop'' up antibodies produced due to maternal-fetal red cells incompatibilty and protecting subsquent pregancies. I can assure you that the present husband is also Rhesus neg. Again, there's no way the previous babies were Rhesus positive.

sgtponzihater1:


Where exactly are u driving at, asking a medical professional all these questions, like u are his lecturer. If a medical professional doesn't know the difference between disease (SC, SThal etc), and Anaemia( ,SS), then medicine in Nigeria is bleak. I follow Nigerian doctors and it's time for a change. Medical jousting, slandering, and name calling is at its best in Nigeria. These have to stop.

On the contrary, I have no interest in slandering anyone and you are wrong to assume that all doctors know this.

peacettw:


On the contrary, I have no interest in slandering anyone and you are wrong to assume that all doctors know this.

My dear I can assure you that ALL Doctors know this. Peace

Thanks OP...you have just cleared my confusion. That first thread messed my mind up I swearit .

Just to add to this as it is a very important topic. While there are other haemoglobinopathies (abnormal haemoglobins) apart from the well known and most common sickle haemoglobinopathies, these other types are not common among black Africans. Haemoglobin S and C are the types commonly found among black Africans. So it will still be VERY unusual for a purely Nigerian couple AA + AS to have an 'SS' child and should be investigated further if it happens.

ryom:
Just to add to this as it is a very important topic. While there are other haemoglobinopathies (abnormal haemoglobins) apart from the well known and most common sickle haemoglobinopathies, these other types are not common among black Africans. Haemoglobin S and C are the types commonly found among black Africans. So it will still be VERY unusual for a purely Nigerian couple AA + AS to have an 'SS' child and should be investigated further if it happens.

God bless you bro. You garrit. Social media will mislead a lot of innocent Nigerians. I was taught in medical school not to completely trust every article I see on the internet cos any quack could open Google and upload incorrect assertions. I was taught to even double-check or tripple check even the so-called medical journals!

.

corisande:


I am AC. Growing up i always knew my genotype to be AA. I did about 3 genotype testing in 3 different labs and it came back as AC.

So how did you assume your genotype was AA while growing up?

peacettw:
An op in an earlier thread tried his best to pass across an important message which was misconstrued.
https://www.nairaland.com/3922963/yes-it-not-impossible-aa


I understood his line of thought and tried replying to some who didn't understand him but along the line thought it better to create a new thread.

Below is what the op was trying to explain in layman's terms.

Our people wrongly believe that the only Sickle cell disease out there is SS. In truth, there are many 'combinations' like SC, SB-thal, SD punjab etc. (notice they all have one thing in common, at least one S in the combination)

Now let's put our heads together, how do you think people get these other types? ....
Ans: exactly the same way you get the SS.

So, if you are AS and get married to AC, AB-thal, or Ad punjab, u stand a risk of getting a child with Sickle cell disease. It's that simple.

Another question... How many of our labs here in Nigeria do you think can correctly detect AC, AB-thal, or Ad punjab?
Ans: Basically a few. I saw my first SC in a px 2 years ago in a 17 year old who was told her whole life that she was AS.
Most labs can't pick up the C, b thal or d punjab, once they see an A with no S, they automatically assume it to be AA but in truth might actually be AC, AB-thal, or Ad punjab.

In essence, it is possible for 'AA' (wc we know now might actually be AC, AB-thal, or Ad punjab) to get married to AS and give birth to SC, SB-thal, SD punjab.. (wc again our labs will incorrectly call SS since they lack the proper equip to detect the C, b thal or d punjab and seeing one S and no A will call automatically it SS).

If you are in doubt, then recheck your genotypes in a center with the right equipments.


I hope I have sufficiently cleared the air. Now, please go and spread the word and stop castigating that poor innocent woman.


Cc: seun, mynd44, lalasticlala

I didnt know this thread happened. Great job op. And i agree u did a better job at breaking it down, sadly some will still not be open enough to accept the information. Welldone ma