The parasites in mosquitos that spread malaria belong to the Plasmodium genus. Over 100 types of Plasmodium parasite can infect a variety of species. Different types replicate at different rates, changing how quickly the symptoms escalate, and the severity of the disease.

Five types of Plasmodium parasite can infect humans. These occur in different parts of the world. Some cause a more severe type of malaria than others.

Once an infected mosquito bites a human, the parasites multiply in the host's liver before infecting and destroying red blood cells.

In some places, early diagnosis can help treat and control malaria. However, some countries lack the resources to carry out effective screening.

A doctor would give this diagnosis when symptoms are present, but no symptoms occur that suggest severe infection or dysfunction of the vital organs.

This form can become severe malaria without treatment, or if the host has poor or no immunity.

Symptoms of uncomplicated malaria typically last 6 to 10 hours and recur every second day.

Some strains of the parasite can have a longer cycle or cause mixed symptoms.

As symptoms resemble those of flu, they may remain undiagnosed or misdiagnosed in areas where malaria is less common.

In uncomplicated malaria, symptoms progress as follows, through cold, hot, and sweating stages:

a sensation of cold with shivering
fever, headaches, and vomiting
seizures sometimes occur in younger people with the disease
sweats, followed by a return to normal temperature, with tiredness
In areas where malaria is common, many people recognize the symptoms as malaria and treat themselves without visiting a doctor.

Severe malaria
In severe malaria, clinical or laboratory evidence shows signs of vital organ dysfunction.

Symptoms of severe malaria include:

fever and chills
impaired consciousness
prostration, or adopting a prone position
multiple convulsions
deep breathing and respiratory distress
abnormal bleeding and signs of anemia
clinical jaundice and evidence of vital organ dysfunction
Severe malaria can be fatal without treatment.

PREVENTION
The Centers for Disease Control advise travelers to take the following precautions:

find out what the risk of malaria is in the country and city or region they are visiting
obtain SUPPLIMENTS FOR antimalarial before leaving home, to avoid the risk of buying counterfeit drugs while abroad
consider the risk for individual travelers, including children, older people, pregnant women, and the existing medical conditions of any travelers
Travelers to places where malaria is prevalent should take precautions, for example, using mosquito nets.
Travelers to places where malaria is prevalent should take precautions, for example, using mosquito nets.
ensure they will have access to preventative tools, many of which are available to purchase online, including insect repellants, insecticides, pre-treated bed nets, and appropriate clothing
be aware of the symptoms of malaria
In emergency situations, local health authorities in some countries may carry out "fogging," or spraying areas with pesticides similar to those used in household sprays.

The WHO points out that these are not harmful for people, as the concentration of pesticide is only strong enough to kills mosquitoes.

While away, travelers should, where possible, avoid situations that increase the risk of being bitten by mosquitoes. Precautions include taking an air-conditioned room, not camping by stagnant water, and wearing clothes that cover the body at times when mosquitoes are most likely to be around.

For a year after returning home, the traveler may be susceptible to symptoms of malaria. Donating blood may also not be possible for some time.


Causes
Malaria happens when a bite from the female Anopheles mosquito infects the body with Plasmodium. Only the Anopheles mosquito can transmit malaria.

The successful development of the parasite within the mosquito depends on several factors, the most important being humidity and ambient temperatures.

When an infected mosquito bites a human host, the parasite enters the bloodstream and lays dormant within the liver.

The host will have no symptoms for an average of 10.5 days, but the malaria parasite will begin multiplying during this time.

The liver then releases these new malaria parasites back into the bloodstream, where they infect red blood cells and multiply further. Some malaria parasites remain in the liver and do not circulate til later, resulting in recurrence.

An unaffected mosquito acquires parasites once it feeds on a human with malaria. This restarts the cycle.

Diagnosis
Early diagnosis is critical for recovery from malaria.

Anyone showing signs of malaria should seek testing and treatment immediately.

The WHO strongly advise confirmation of the parasite through microscopic laboratory testing or by a rapid diagnostic test (RDT), depending on the facilities available.

No combination of symptoms can reliably distinguish malaria from other causes, so a parasitological test is vital for identifying and managing the disease.

In some malaria-endemic areas, such as sub-Saharan Africa, the disease's severity can cause mild immunity in a large proportion of the local population.

As a result, some people carry the parasites in their bloodstream but do not fall ill.

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