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Your Chances Of Pregnancy At 40 And Above - Health - Nairaland

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Your Chances Of Pregnancy At 40 And Above by orispee58(m): 10:41am On Jul 06, 2019
Dr. Abayomi Ajayi

How late can a woman delay childbearing? Can it be too late to become a mother? Perhaps you’ve delayed starting a family because of your career, you weren’t in a stable relationship, or you simply weren’t ready to be a mother and you are worried you might have waited too long. There are many reasons you may decide to delay pregnancy, but what does this mean for your chances of motherhood?

Let’s start by looking at your chances of getting pregnant at 40 and above naturally. Certainly if you are over 40 you can still conceive naturally; however, your chances of getting pregnant would have decreased significantly over the decades.
As a woman, your fertility begins to decline around the age of 30, and becomes more rapid at 35 until age 40, when your fertility has reduced by half.

When you’re around 30 years old or so, there is a 25 per cent chance of getting pregnant per cycle compared to when you’re 40 and have a 10 per cent chance of getting pregnant per cycle.

So why are your chances of getting pregnant decreasing? The explanation is quite straightforward. As a woman, you were born with all your eggs which could be 300,000 – 400,000 and certainly a decline in fertility is natural because there is a decrease in the number of eggs with time.

So at 40 you probably still have around 10,000 eggs, which is just three or four per cent of the original 300,000 – 400,000 present at the onset of puberty.

The follicles that form the eggs also accumulate mutations overtime – meaning that there is a breakdown of DNA repair mechanisms – so the rate of failed fertilisation, miscarriage and birth defect increases as you get older.

One of the ways to increase your chances of getting pregnant at 40 quickly is to make sure that you are having unprotected sex at the right time in your cycle.

However, if you have tried everything and failed to get pregnant after six months or more of regular unprotected sex, you need to seek medical advice along with your spouse or sex partner.

As your chances of falling pregnant naturally over 40 is now below 10 per cent, you can increase your chances with assisted reproductive technologies such as IVF.

Older women like you could opt to use their own eggs, if they are still viable and do not need to consider egg donation option. Such women have achieved pregnancy with IVF using their own eggs. However, it is important to note that your chance of IVF success is dependent on your own specific circumstances. Factors like your medical history and fertility all need to be considered.

We can help eliminate genetic disorders. New technology has made it possible for us to identify embryos that can bear some diseases in life, so we can easily identify and select the embryos that are free. We call it Pre-implantation Genetic Diagnosis.

It is the process of removing a cell from an in vitro fertilisation embryo for genetic testing before transferring the embryo to the uterus. Pre-implantation Genetic Screening is the process of testing for overall chromosomal normalcy in embryos. We know that we all have 23 pairs of chromosomes in our cell nuclei. The last pair is the sex chromosomes, so one of the things you also get from that is you can tell the gender of the embryo from that when you can see these 23 pairs of chromosomes. Before a few years ago, we could only see about five pairs of chromosomes, but now with technology we can see all the 23 pairs. So apart from gender we can look at every disease that the embryo can be predisposed to.

Expectedly, older women are worse off with IVF. But with high-tech advancements such as PGD and PGS, we can improve their chances but they need to have sufficient number of embryos for the selection process to be possible. In screening, we are looking at the number of chromosomes and their arrangement because we have seen that the greatest reason why IVF fails is because there are problems in the arrangement of the chromosomes. We now know that 70-75 per cent of embryos produced in our labs can never become babies because of this problem that increases with the age of the woman and this is one of the reasons why we say older women are worse off with IVF and with reproduction generally.

We have seen why it is so now, especially with the structural or numerical errors in the arrangement of chromosomes, so one is able to pick out the ones that cannot become babies to start with, apart from the ones that have diseases. We can tell which is which.

There are some diseases that we have been able to see their profile. In Sickle Cell Disease, for instance, it is just one amino acid replacing another. We can see that amino acid has a problem. We can see if some embryos have Down’s syndrome. There are about 600 diseases, including cancers that we have been able to see what their profiles look like, so we can identify such disorders and we do not use such embryos.

The diseases that PGD can diagnose are called single gene disorders. When it is one gene that has a disorder all you need to do is find that gene and that is why the profile of the disease has been identified. We are always saying that diseases require external factors for them to manifest; those are the ones you are in control of to make sure that you do not feed the illness.

There are many gene mutations, every normal person carries three to five mutations; it is normal. The problem only comes when we marry somebody who has the same mutations like we do, so we turn from being carriers into having offspring that exhibit the disease. This can be used also in people that are using donor eggs as well as own eggs.

You could be a healthy woman who is carrying mutations in your genes. You are normal and healthy, but the problem only comes if your husband or the husband of the woman that wants to use your egg carries the same mutation. Then the baby they are going to have will be born with the disease. A good example is albinism. That’s why two people who are not albinos can produce an albino child because they both carry the albino gene even though they are not manifesting as albinos.

IVF could fail for several reasons and for it to succeed for you; you need to make decisions that may not be easy sometimes.

For instance, at 46, it may not be reasonable to insist on doing IVF using your own eggs after all the tests have shown that your eggs are unviable and you need to use donor eggs. We know that the success rate of a 46-year-old using her own eggs is less than five per cent.

For you to succeed with IVF, you need to listen to your doctors, ask questions and try to make informed decisions. The work of a good IVF clinic is to support you make these decisions. That is why we have counsellors, acupuncturists, all kinds of specialists that can help you come to terms with these decisions. We do not want you to be pushed into making these decisions.

You need to look at the implications. Even saying you do not want any treatment is a decision, but are you sure you know the implications? These are things the counsellors will help you with. And even if you make the right decision, if you are below 35, be prepared to do two IVF cycles. If you are above 35, be prepared to do three cycles of IVF because IVF does not mean we have kept a baby somewhere to give to you. It is better to be prepared to go the full journey.

Some couples are lucky. They do one cycle and conceive. Some others have done two to four cycles and have two to four babies and we have those that have done more than five cycles and have no baby to show. So many things are involved.

If the clinic is good, it is the husband and wife that are actually the determinants of their own success because it is the sperms and eggs that you give us that we can work with. Everybody contributes to their own success rate, the quality of the sperm and eggs.

Technology can help the sperm, but there is nothing that can be done about the egg. The quality of the egg is the priority in determining the success.

https://punchng.com/your-chances-of-pregnancy-at-40-and-above

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Re: Your Chances Of Pregnancy At 40 And Above by Opexzy: 4:44pm On Oct 02, 2021
Human anatomy is being affected in this our generation... And some women even find it difficult to concieve at prime age.
If you are a lady and your menstrual cycle is irregular at young age, your breast secretes milk even when you are not pregnant. It might be a sign of early menopause..

So many ladies are walking around ignorantly with symptoms that points to early sign of menopause today but they are more interested in getting iPhone 13, the next wig and bags. These type of ladies are the ones that will give that innocent man sleepless night because of their negligence.

If I hear wedding from your mouth when you never get belle.

97 Likes 5 Shares

Re: Your Chances Of Pregnancy At 40 And Above by Bobotic(m): 4:44pm On Oct 02, 2021
My future wife hope you're reading it cool

61 Likes 2 Shares

Re: Your Chances Of Pregnancy At 40 And Above by Mrquote: 4:44pm On Oct 02, 2021
Hmmm
Re: Your Chances Of Pregnancy At 40 And Above by JovialJune(f): 4:45pm On Oct 02, 2021
Right, there should also be an extensive awareness of male infertility like low sperm count and the rest, the rate at which men consume drugs and alcohol with reckless lifestyle which affect their fertility is worrisome, they don't know this, they ignorantly marry their wives and assume only women have this problem. A doctor friend told me of infertility cases caused by men, who refuses to tell their spouse, they prefer the blame to be heaped on her, God help us.

124 Likes 11 Shares

Re: Your Chances Of Pregnancy At 40 And Above by FalseProphet1(m): 4:45pm On Oct 02, 2021
This is human report, with fervent prayers you can still get pregnant even at 80.

This I have seen.

45 Likes 1 Share

Re: Your Chances Of Pregnancy At 40 And Above by Aktecco123(m): 4:45pm On Oct 02, 2021
Okay

1 Like

Re: Your Chances Of Pregnancy At 40 And Above by BigJoe19: 4:45pm On Oct 02, 2021
Pocohan.tas, Saphiere, Biglittlelois, Amazon.Topaz need this article more.

53 Likes 2 Shares

Re: Your Chances Of Pregnancy At 40 And Above by LaSenior: 4:45pm On Oct 02, 2021
cheesy
Re: Your Chances Of Pregnancy At 40 And Above by pacespot(m): 4:46pm On Oct 02, 2021
Hmm
Re: Your Chances Of Pregnancy At 40 And Above by ofiko123(m): 4:46pm On Oct 02, 2021
Can anyone really get pregnant at age 40..

4 Likes

Re: Your Chances Of Pregnancy At 40 And Above by okaforlazarus90(m): 4:47pm On Oct 02, 2021
So, the bottomline of it all be say, guys no get any problem!

13 Likes

Re: Your Chances Of Pregnancy At 40 And Above by MANNABBQGRILLS: 4:47pm On Oct 02, 2021
Reading

3 Likes 2 Shares

Re: Your Chances Of Pregnancy At 40 And Above by dprice(m): 4:47pm On Oct 02, 2021
A
Re: Your Chances Of Pregnancy At 40 And Above by RichThugg: 4:48pm On Oct 02, 2021
You mean your chances of bearing a child at your newspaper stage?? undecided


grin

6 Likes 1 Share

Re: Your Chances Of Pregnancy At 40 And Above by Nigerialabalaba: 4:48pm On Oct 02, 2021
Nice .

1 Like

Re: Your Chances Of Pregnancy At 40 And Above by Drizzy5001(m): 4:49pm On Oct 02, 2021
I've seen a woman that gave birth @43 so it's still possible

40 Likes 2 Shares

Re: Your Chances Of Pregnancy At 40 And Above by Icumsa45(m): 4:49pm On Oct 02, 2021
Abeg no discourage me, the woman I am in love with is presently 31.

40 Likes 3 Shares

Re: Your Chances Of Pregnancy At 40 And Above by COdeGenesis: 4:49pm On Oct 02, 2021
What if one stores the egg to use in the futue

2 Likes 1 Share

Re: Your Chances Of Pregnancy At 40 And Above by Waiq: 4:49pm On Oct 02, 2021
God way different sha

17 Likes 2 Shares

Re: Your Chances Of Pregnancy At 40 And Above by McOluOmo: 4:49pm On Oct 02, 2021
Noted









Guys wey no get girlfriend get peace of mind

7 Likes

Re: Your Chances Of Pregnancy At 40 And Above by vinceyinnovation: 4:50pm On Oct 02, 2021
H
Re: Your Chances Of Pregnancy At 40 And Above by crackhouse(m): 4:50pm On Oct 02, 2021
Tell them
Re: Your Chances Of Pregnancy At 40 And Above by WibusJaga: 4:50pm On Oct 02, 2021

The older, the higher the risk to the mother & baby.
So think twice b4 bringing a baby with health challenge into this world. To have baby is not a do or die affair.

12 Likes 1 Share

Re: Your Chances Of Pregnancy At 40 And Above by AreaFada2: 4:51pm On Oct 02, 2021
Good thread.
Re: Your Chances Of Pregnancy At 40 And Above by iamyemiakins(m): 4:52pm On Oct 02, 2021
There's no laid down procedure that works best, a woman can even give birth to triplets at 40 & above without any special procedure.

Na just God and genes jare

NoFucksToGive:


Alot of illiterates on this forum

Do you know what IVF is at all? Or because she didn't tell you she did IVF because she knows your brain can't understand what it is doesn't mean she didn't do it

Education is key o
Learn how to read and understand, I started with a statement.

I know about IVF and have heard a lot of testimonies from that, but I'm talking generally about females above 40 years, not necessarily TTC that have been trying to get pregnant for a long time and starts exploring different options.

14 Likes 1 Share

Re: Your Chances Of Pregnancy At 40 And Above by Henix(m): 4:52pm On Oct 02, 2021
Informative!
My own advice is that ladies should stop being too selective in accepting their prospective husbands. Let them get married as early as possible, since they are more fruitful at their younger age

22 Likes 7 Shares

Re: Your Chances Of Pregnancy At 40 And Above by FreeStuffsNG: 4:52pm On Oct 02, 2021
If you're ttc and over 40, what he is trying to inform you ,albeit codedly, is that your chances of pregnancy increases with your income and that of your spouse too.

Truth be told, Assisted reproduction through IVF costs money cheesy He is promoting his business and it costs money even to get it to the frontpage of nairaland wink

Here is free book on business ideas & money sources directory for you, it's 100% free!
https://www.nairaland.com/6666800/looking-business-ideas-money-fund.

8 Likes

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