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Coronavirus: Study Explains Why Men Are Affected More Than Women by Macsjebs: 1:22am On Mar 03, 2020
Like the 2003 Sars outbreak and the 1918 Spanish flu pandemic, death rates among male victims are far higher

The coronavirus that originated in China has spread fear and anxiety around the world. But while the novel virus has largely spared one vulnerable group — children — it appears to pose a particular threat to middle-aged and older adults, particularly men.

This week, the Chinese Centre for Disease Control and Prevention (CDC) published the largest analysis of coronavirus cases to date. Although men and women have been infected in roughly equal numbers, researchers found, the death rate among men was 2.8 per cent, compared with 1.7 per cent among women.

Men also were disproportionately affected during the Sars and Mers outbreaks, which were caused by coronaviruses. More women than men were infected by Sars in Hong Kong in 2003, but the death rate among men was 50 per cent higher, according to a study published in the Annals of Internal Medicine.

Some 32 per cent of men infected with Middle East respiratory syndrome died, compared with 25.8 per cent of women. Young adult men also died at higher rates than female peers during the influenza epidemic of 1918.

A number of factors may be working against men in the current epidemic, scientists say, including some that are biological, and some that are rooted in lifestyle.

When it comes to mounting an immune response against infections, men are the weaker sex.

“This is a pattern we’ve seen with many viral infections of the respiratory tract — men can have worse outcomes,” said Sabra Klein, a scientist who studies sex differences in viral infections and vaccination responses at the Johns Hopkins Bloomberg School of Public Health.

“We’ve seen this with other viruses. Women fight them off better,” she added.

Women also produce stronger immune responses after vaccinations, and have enhanced memory immune responses, which protect adults from pathogens they were exposed to as children.

“There’s something about the immune system in females that is more exuberant,” said Dr Janine Clayton, director of the Office of Research on Women’s Health at the National Institutes of Health.

But there’s a high price, she added: Women are far more susceptible to autoimmune diseases, like rheumatoid arthritis and lupus, in which the immune system shifts into overdrive and attacks the body’s own organs and tissues.

Nearly 80 per cent of those with autoimmune diseases are women, Clayton noted.

The reasons women have stronger immune responses aren’t entirely clear, and the research is still at an early stage, experts caution.

One hypothesis is that women’s stronger immune systems confer a survival advantage to their offspring, who imbibe antibodies from mothers’ breast milk that help ward off disease while the infants’ immune systems are still developing.

A stew of biological factors may be responsible, including the female sex hormone estrogen, which appears to play a role in immunity, and the fact that women carry two X chromosomes, which contain immune-related genes. Males, of course, carry only one.

Experiments in which mice were exposed to the Sars coronavirus found that the males were more susceptible to infection than the females, a disparity that increased with age.

The male mice developed Sars at lower viral exposures, had a lower immune response and were slower to clear the virus from their bodies. They suffered more lung damage, and died at higher rates, said Dr Stanley Perlman, a professor of microbiology at the University of Iowa who was the senior author of the study.

When researchers blocked estrogen in the infected females or removed their ovaries, they were more likely to die, but blocking testosterone in male mice made no difference, indicating that estrogen may play a protective role.

“It’s an exaggerated model of what happens in humans,” Dr Perlman said. “The differences between men and women are subtle — in mice, it’s not so subtle.”

Health behaviours that differ by sex in some societies may also play a role in disparate responses to infections.

China has the largest population of smokers in the world — 316 million people — accounting for nearly one-third of the world’s smokers and 40 per cent of tobacco consumption worldwide. But just more than 2 per cent of Chinese women smoke, compared with more than half of all men.

Chinese men also have higher rates of Type 2 diabetes and high blood pressure than women, both of which increase the risk of complications following infection with the coronavirus. Rates of chronic obstructive pulmonary disease are almost twice as high among Chinese men as among women.

In the United States, women are more proactive about seeking health care than men, and some small studies have found the generalisation applies to Chinese students at universities in the United States, as well.

In unpublished studies, Chinese researchers have emphasised that patients whose diagnoses were delayed, or who had severe pneumonia when they were first diagnosed, were at greatest risk of dying.

One study of 4,021 patients with the coronavirus emphasised the importance of early detection, particularly in older men. And men have been turning up in hospitals with more advanced disease.

But in areas of China outside Hubei province, the epidemic’s epicentre and where the majority of those affected are concentrated, the patterns are different: The illness appears to have dramatically lower mortality rates, and men are being infected at much higher rates than women, according to the Chinese CDC analysis.

Men may have a “false sense of security” when it comes to the coronavirus, said Akiko Iwasaki, a professor of immunology at Yale University who studies why some viruses affect women more severely.

Gathering and analysing data about the new virus by sex is important both for the scientists studying it and for the general public, experts said.

Since the start of the outbreak, for example, public health officials have emphasised the importance of washing hands well and often, to prevent infection. But several studies have found that men — even health care workers — are less likely to wash their hands or to use soap than women, Dr Klein said.

“We make these broad sweeping assumptions that men and women are the same behaviourally, in terms of comorbidities, biology and our immune system, and we just are not,” Dr Klein said.
Source: https://www.independent.co.uk/news/science/coronavirus-men-women-immune-symptoms-outbreak-a9364641.html

5 Likes

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Kreamie(m): 5:36am On Mar 03, 2020
Mehhhnnnn!!!! cry

Life is so tough on men

132 Likes 2 Shares

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by KangaIye: 5:36am On Mar 03, 2020
shocked
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by careytommy37(m): 5:37am On Mar 03, 2020
shocked shocked shocked shocked shocked

Say what?

7 Likes 1 Share

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Elvis2kay: 5:38am On Mar 03, 2020
embarassed
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Ofunaofu: 5:38am On Mar 03, 2020
shocked
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by safety247: 5:38am On Mar 03, 2020
Noted

1 Like

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by GEOANDSONS: 5:39am On Mar 03, 2020
To be a man is not easy

Man go fight for money (wetin man go do)
Man go fight for woman (wetin man go do)
Man go fight for business (wetin man go do)
Man go fight for nonsense (wetin man go do) uh uh
Body don dey tire
Body no be firewood (wetin man go do)
Body don dey tire
Body no be firewood (wetin man go do oo)
Wetin man go do oo do oo
Wetin man go do doo oo
Wetin man go do oo do oo do oo do oo do oo doo
Wetin man go do, wetin man go do


Curled from Burna boy's Wetin man go do

Home and Office Furnitures available

43 Likes 4 Shares

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Akile1: 5:39am On Mar 03, 2020

4 Likes

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Nobody: 5:40am On Mar 03, 2020
Summary points (for the 'This article is too long' people)

1. Men have a relatively weaker immune system than women (women's stronger immune system may be due to the fact that they have estrogen, and also have 2 x chromosomes...X chromosomes carry immune factors)


2.Health behaviours...men more likely to be involved in activities detrimental to health than women. (Men eat, drink and smoke anything..leading to higher rates of lifestyle diseases like type 2 diabetes...which reduce resistance to the virus).

Men also are worse on personal hygeine compared to women (eg don't wash their hands regularly).which increases chances of infection



N. B. I am merely summarising the article, not providing talking points for man vs woman fight. Thank you

197 Likes 9 Shares

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Goldenheart(m): 5:40am On Mar 03, 2020
He who is gonna die is gonna die tongue

Eni maku, aku

6 Likes 1 Share

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by WonderManly(m): 5:41am On Mar 03, 2020

3 Likes

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by SenecaTheYonger(m): 5:41am On Mar 03, 2020
...

16 Likes

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by jordyspices: 5:42am On Mar 03, 2020
Nothing wey man no go see right from time of adam

1 Like

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Sugargal: 5:44am On Mar 03, 2020
It's good to see women winning somewhere. @all, eat healthy, stop smoking and drinking excessively. Do all you can to build your immunity, it will be useful when you need it.

7 Likes 1 Share

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by bluefilm: 5:45am On Mar 03, 2020
Chai

Men don suffer.

Anyway sha, thank God say African men like us are still spared from the disease. wink
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Auxtin85(m): 5:46am On Mar 03, 2020
May God help us all
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by amiibaby(f): 5:46am On Mar 03, 2020
Men are the weaker sex wow

7 Likes

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by adamooye: 5:47am On Mar 03, 2020
God help men

1 Like

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by njideoby(f): 5:47am On Mar 03, 2020
Men you see your lives. Who’s now the weaker sex.
Haven’t you observe what happens when fathers are sick compared to when mothers are sick?
The same malaria but father will look like he will die the next minute.

59 Likes 7 Shares

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Victorchuks4(m): 5:47am On Mar 03, 2020
Life is always hard on men... During war men are been slaughtered during heavy duty work men are involved.. Chai!!! But in my next world I will always be a man. Men's world is the best

25 Likes

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Lumig: 5:47am On Mar 03, 2020
... Is this not a ploy to reduce the population of men?

3 Likes

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by AntiChristian: 5:53am On Mar 03, 2020
Men Sha!
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Richieniit: 5:55am On Mar 03, 2020
Is not about the coronavirus that scares me or the spread across nations.. my biggest fear is NO VACCINE YET embarassed Even the USA are yet to give update abt counter measures or update abt VACCINE to cure...
Definitely we all know the spread cannot be contained
The whole world should be scared [color=#990000][/color]

3 Likes 1 Share

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by olu77(m): 5:55am On Mar 03, 2020
It's men's world
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Iamvetlander(m): 5:56am On Mar 03, 2020
,
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by EdiskyHarry: 5:57am On Mar 03, 2020
Hmmm, Nawa o
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by IntellectOzone(m): 5:58am On Mar 03, 2020
grin

Men are Merlin of fuvkaty
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by englishmart(m): 5:58am On Mar 03, 2020
Simply because men go out more.
Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Geesaintagape: 5:59am On Mar 03, 2020
Being a man is a thug of.war

1 Like

Re: Coronavirus: Study Explains Why Men Are Affected More Than Women by Etinosa1234: 5:59am On Mar 03, 2020
njideoby:
Men you see your lives. Who’s now the weaker sex.
Haven’t you observe what happens when fathers are sick compared to when mothers are sick?
The same malaria but father will look like he will die the next minute.

We are not talking about ur father

Read and understand

39 Likes

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