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Marijuana As Medicine - Drug Facts - Health - Nairaland

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Marijuana As Medicine - Drug Facts by Irfan069: 7:16am On Aug 20
The term medical marijuana refers to the utilization of the whole raw marijuana plant, or its basic extracts, to treat certain symptoms of diseases and other disorders. The US Food and Drug Administration (FDA) has not recognized or approved the marijuana plant as drugs.
However, scientific study of the chemicals in marijuana, called cannabinoids, has led to the FDA's approval of two pill-form drugs that contain cannabinoids. More drugs could also be approved as research continues.
Since the marijuana plant contains chemicals which will be helpful in treating a good sort of illnesses and symptoms, many argue that its use for medicinal purposes should be legalized. In fact, more and more states have legalized marijuana for medicinal use.
Why hasn't the FDA approved the marijuana plant as a medicine?
The FDA requires rigorous studies (clinical trials) on hundreds and even thousands of individuals to work out the advantages and risks of a possible drug. So far, researchers haven't conducted enough large-scale clinical trials to point out that the advantages of the marijuana plant (not its cannabinoid ingredients) outweigh the risks in patients for whom the treatment is indicated.
In our publication Drug Facts: Marijuana, you'll find more information about the various effects marijuana has on behavior and physical and psychological state.
What are cannabinoids?
Cannabinoids are chemical substances related to delta-9-tetrahydrocannabinol (THC), the most psychoactive ingredient in marijuana that alters the mind and generates the high or "high" in its user. The marijuana plant contains quite 100 cannabinoids. Furthermore, both illegal manufacturers and scientists have produced many laboratory cannabinoids. a number of these cannabinoids are extremely powerful and cause serious health effects when used improperly.
What benefit could cannabinoids have as medicine?
Currently, the 2 main cannabinoids within the marijuana plant that are of medicinal interest are THC and CBD.
THC can increase appetite and reduce nausea. It also can reduce pain, inflammation (swelling and redness), and muscle control problems.
Unlike THC, CBD may be a cannabinoid that doesn't cause a high , meaning it's not mind-altering. It are often helpful in reducing pain and inflammation and in controlling epileptic seizures, and should even be wont to treat mental disease and addictions.

Many researchers, including researchers funded by the National Institutes of Health (NIH), still explore the potential uses of THC, CBD, and other cannabinoids for therapeutic purposes.
What medicines contain cannabinoids?
Two FDA-approved drugs — dronabinol and abalone — contain THC. They’re treatments for nausea caused by chemotherapy and to extend appetite in patients who have suffered extreme weight loss thanks to AIDS. Continuing research could lead on to the invention of other drugs.
The UK, Canada, and a number of other European countries have approved nabiximols (Sati vex®), a mouth spray containing THC and CBD. It’s wont to treat muscle control problems caused by MS, but it's not approved by the FDA.
Epidiolex, a liquid CBD-derived medication for the treatment of certain sorts of childhood epilepsy, is being studied in clinical trials but has not yet been approved by the FDA.
References
Bach Huber MA, Salome B, Cunningham CO, Barry CL. Medical cannabis laws and opioid analgesic overdose mortality within the us, 1999-2010. JAMA Intern Med. 2014; 174 (10): 1668-1673. doi: 10.1001 / jamainternmed.2014.4005
Chelsea L. Shaver, Corey S. Davis, Sanford C. and Keith Humphreys, between medical cannabis laws and opioid overdose mortality has reversed over time, PNAS June 25, 2019 116 (26) 12624-12626.
Scott KA, Dallies AG, Liu WM. the mixture of cannabidiol and Δ9-tetrahydrocannabinol enhances the anticancer effects of radiation in an orthotropic murine gloom model. Moll Cancer There. 2014; 13 (12): 2955-2967. Doe: 10.1158 / 1535-7163.MCT-14-0402
Tress V, Campolongo P, Casino T, et al. Effects of perinatal exposure to on the emotional reactivity of the offspring: a longitudinal behavioral study in Westar rats. Psychopharmacology (Burl). 2008; 198 (4): 529-537. Doe: 10.1007 / s00213-008-1162-3

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