Alzheimer's disease is One of the diseases slotxo caused by genetic mutations With various factors to promote such as increasing age Abnormal genetic code Existing chronic disease Had head or brain injury, smoking, severe brain infection
Currently, mutations (Mutation) of Alzheimer's-related genes such as Apo E, APP, PSEN1 and PSEN2, are a group of genes found in people with a family history of Alzheimer's. Tor
Alzheimer's disease, there is no cure for this drug. They can only slow down the disease from progressing and have a better quality of life.

Alzheimer's Disease (Alzheimer's Disease)
Is one of the most common dementia (dementia), accounting for 60-80% of all dementia. By those suffering from this disease The brain will have a buildup of proteins called Beta-amyloid (beta-amyloid) resulting in dementia and atrophy of the brain cells. Including damage communication between brain cells This was because it was found that there was a decrease in the neurotransmitter that directly affects memories called acetylcholine.

Protein buildup Beta-amyloid This starts with the hippocampus of the brain. It will help make short-term memory become long-term memory. (Which is essential to learning new information) is a process called. “Consolidation”, although the hippocampus is not a repository of information. But if this part of the brain is atrophy or damaged Patients develop memory problems, especially short-term memory, such as forgetting about the last 10-15 minutes before they did something or talking to someone. (Completely forgotten and not imagined), then the damage will spread to other brain regions. And affect learning Their feelings, thoughts, languages ​​and behaviors result in an inability to take care of themselves. Until it is a burden for the family

However, Alzheimer's disease is one of the most common genetic mutations. There are many factors to promote (Complex Disorders or Multifactorial Inheritance) such as increased age. The presence of certain congenital genetic code Existing chronic diseases (such as hyperlipidemia, diabetes, high blood pressure Depression or chronic stress) a certain condition of the body or risky behavior, such as injury to the head or brain, severe smoking, brain infection.

Currently, mutations (Mutation) of Alzheimer's-related genes such as Apo E, APP, PSEN1, and PSEN2 are genes found in people with a family history of Alzheimer's. A Which the gene test for this risk It is another way that will help us to be careful with our life carefully. Because if the test results come out to find risks, it means that we are at a disadvantage than the general public from birth. Because the chances of birth are greater than others, adjusting some lifestyle habits will help slow down the exposure of this disease before old age. (Initial risk test from assessment)


What does sour milk have to do with it?
There is currently no cure for Alzheimer's disease. If found to be a disease They can only slow the disease progression and have a better quality of life. But has a world-class drug research and development team A new drug is being developed to help prevent the build-up of beta-amyloid deposits in the brain, based on research ideas. Some of the mechanisms of the fermented milk microorganism, Streptococcus Thermophilus, have a self-immune defense system. They can edit their own genes in the event of an abnormality or a viral infection. We call that system name CRISPR / Cas9 system (Crisper-Casnine).

The discovery of this CRISPR / Cas9 system with DNA strand synthesis knowledge This allows researchers to modify the DNA sequence in living cells as needed. Whether it is adding, reducing, altering the genetic code. This includes the development of nanoparticles drugs that can pass through the capillary membrane and brain (Blood Brain Barrier) to help restore abnormal cells or genes in the brain. Although not in the foreseeable future yet But it is good news And not just for Alzheimer's disease patients But also other immune system diseases, cancer, AIDS, and other genetic diseases.