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Marriage And The Genotype Question. - Family - Nairaland

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Marriage And The Genotype Question. by donTbone(op): 8:46am On Oct 22, 2015
What prompted me to post this article is that, yesterday, I discovered my GF and I are both AS, which we might be at risk if we go further in marriage. The risk, which I discovered is 25% of 100%. But, is it worth taking?

Love is all we need, yes! but its never enough. As I ponder over it, I thought there should be a way out. Then I think sharing this and asking for advice is gonna help people like me and others a great deal.

Breaking It Down – What is Genotype?

If those alphabet combinations confuse you, then you need to get informed about genotype and pairings. I don’t know enough about it to get technical but I know that there are three major groups of genotype: AA (normal), AS (carrier) and SS (sickler) and there are the less known genotype groups: SC and CC. In the process of impregnation by sexual intercourse, both persons combine genotypes to influence the genotype of the unborn child and using the major groups, it is usually advised medically that intending couples should ascertain their genotype in order not to produce kids with the SS genotype.

Personally, I think most ancient cases of abiku and ogbanje were really cases of SS genotype but I don’t know how my theory would explain the birth of children with incisions that were carved into the corpse of the last abiku…just a passing thought though.

The Genotype Issues

The hope of creating generations of kids living without the SS genotype hinges on humans showing great discretion in marriage choice by carefully selecting and choosing a marriage partner with genotype compatibility as one of the criteria – AA can marry SS, AA can marry AS, AA can marry AA – clear. SS and SS can never marry – that’s a little obvious. AS and SS may be difficult to join in union since the SS person knows firsthand the pains of living with sickly cells. It is therefore the case of AS and AS that makes up genotype and marriage issues.

AS carriers have no issues with being sickly and can live a normal life till adulthood. Without knowledge of the pains of SS sicklers, they usually do not hesitate before going into marriage, but for the recent campaigns about sickle cell. There’s also the hope possibility – by permutation, only one out of four children may be SS: that’s a 25% chance or .25 odds –not bad for a gamble.

The Genotype Reality

All their offspring can turn out to be SS and even one sickly child is enough to cause much emotional stress in the marriage. To know that one is responsible for bringing a sickly child to life is painful but worse still is the knowledge that one foolishly rejected superior intelligence and insisted on going ahead with an AS/AS marriage. Matters can be made worse if it took a lot of persuasion on the part of one partner before the other agreed – one person will have to do the duty of encouraging the other and shouldering the blame. An enlightened society is also not likely to show support in this age: “didn’t they know they should have gone for genotype tests before marriage?”

Medical Science to the Rescue

There are processes by which couples of AS genotypes can get married and produce children who do not have sickly cells. One is called amniocentesis and the other is called chorionic villus sampling test (CVS test) – the latter can be done between the 8th and 12th week of pregnancy while the former has to wait a longer period – 15th and 20th week. Both carry risks of less than 5% (according to some authorities) and can determine if the fetus (unborn child) has any defects, including the SS genotype. If the fetus is sickly, it can be terminated.

There’s also a very expensive procedure where the fertilising sperm and egg are carefully selected and bred outside the woman’s body before it is taken back into her womb as a healthy fetus.

Does Spirituality Help with Genotype Incompatibility?

Yes, it does. I heard of a couple from Borno State last year whose SS genotype children were miraculously healed and their genotype became AA but sadly, this is an exception these days because such events require a level of faith maturity to occur.

The other way religion helps is that it can help the parents to cope with the sickliness of their kid(s) or even their death. Guilt will however play a role if they both ignored the consequences of such a marriage and selfishly went ahead despite their wrong genotype match.

I'd love some serious minded couples to please advice and contribute on it. As for those that are single or don't know their spouse genotype yet, better to ask now before its too late. God bless us all!

cc: lalasticlala,DONSMITH,adetayour
Re: Marriage And The Genotype Question. by INTROVERT(f): 8:47am On Oct 22, 2015
reading
Re: Marriage And The Genotype Question. by FruityLass:
Op Op.....

Give the source because you copied and pasted it.
cheesy

And remember to upload the image too tongue

Source:
http://demolarewajudaily.com/lovefriday-marriage-the-genotype-question/
Re: Marriage And The Genotype Question. by Nobody: 9:03am On Oct 22, 2015
Read your post.. Well written..
but then 25% is bad for a gamble
Medical science.... Its expensive and Termination of the pregnancy might not even be the best..
Spirituality.. I believe in miracles, If I want to ask God for a miracle in an issue like this, I would rather ask Him to change one party AS to AA, but for me hoping that He will do it for my child, I wont take that chance...
Both of you should visit sickle cell center and decide if you are willing to take the risk
Re: Marriage And The Genotype Question. by donTbone(op): 9:09am On Oct 22, 2015
favoured234:
Read your post.. Well written..
but then 25% is bad for a gamble
Medical science.... Its expensive and Termination of the pregnancy might not even be the best..
Spirituality.. I believe in miracles, If I want to ask God for a miracle in an issue like this, I would rather ask Him to change one party AS to AA, but for me hoping that He will do it for my child, I wont take that chance...
Both of you should visit sickle cell center and decide if you are willing to take the risk
... cheesy
I would rather ask Him to change one party AS to AA
My partner been wishing for that too!
Re: Marriage And The Genotype Question. by Dyt(f): 9:13am On Oct 22, 2015
Its a serious issue you don't gamble with
Yes love we know but when it starts, it weighs you out, not all are lucky, in some cases both don't even know *naijas incompetence* but in your case, you know and then gambling with it, I dunno about that
On the other hand there are options which you listed out, can you stand her going for termination?
How long do you keep doing that
What if it didn't come after the first

Sorry I am not being negative
There's possibilities too you lucky

I was at the sickle cell clinic, lots of beautiful and handsome intelligent young kids, healthy
You will hardly tell they are warriors
Some been so lucky with no crisis, the parents manage them well
They are like normal child
Every normal child
No descrimination
They are beautiful
Bold
Intelligent
They have a life like any other child

Just sad they are prone to infections and other diseases faster than the rest blood cells

If you can avoid it pls do
Cos I was also at there admission centre and what I saw is heartbreaking
May Almighty Allah not give us the cause to shed tears over pur kids

There are lots of hardship in this part of the world already
And then adding this?
I don't think you wanna go that Lane
Re: Marriage And The Genotype Question. by donTbone(op): 9:25am On Oct 22, 2015
Dyt:
Its a serious issue you don't gamble with
Yes love we know but when it starts, it weighs you out, not all are lucky, in some cases both don't even know *naijas incompetence* but in your case, you know and then gambling with it, I dunno about that
On the other hand there are options which you listed out, can you stand her going for termination?
How long do you keep doing that
What if it didn't come after the first

Sorry I am not being negative
There's possibilities too you lucky

I was at the sickle cell clinic, lots of beautiful and handsome intelligent young kids, healthy
You will hardly tell they are warriors
Some been so lucky with no crisis, the parents manage them well
They are like normal child
Every normal child
No descrimination
They are beautiful
Bold
Intelligent
They have a life like any other child

Just sad they are prone to infections and other diseases faster than the rest blood cells

If you can avoid it pls do
Cos I was also at there admission centre and what I saw is heartbreaking
May Almighty Allah not give us the cause to shed tears over pur kids

There are lots of hardship in this part of the world already
And then adding this?
I don't think you wanna go that Lane
#sighs
Thankx angry
Re: Marriage And The Genotype Question. by isblog(m): 9:26am On Oct 22, 2015
favoured234:
Read your post.. Well written..
but then 25% is bad for a gamble
Medical science.... Its expensive and Termination of the pregnancy might not even be the best..
Spirituality.. I believe in miracles, If I want to ask God for a miracle in an issue like this, I would rather ask Him to change one party AS to AA, but for me hoping that He will do it for my child, I wont take that chance...
Both of you should visit sickle cell center and decide if you are willing to take the risk
Nice contribution I must say
Re: Marriage And The Genotype Question. by Dyt(f): 9:31am On Oct 22, 2015
donTbone:
#sighs
Thankx angry
Its a tough decision
Don't let your case be like had I know

You can go for the options
I think sickle cell clinics offer that egg thing for 2m
Dunno about the tests but last I heard was like 750k
Choice is yours
Love they say conquers all but its not enough

I mother a warrior too
A young vibrant young man
I have been lucky all along
Maybe God is giving me that grace only cos I didn't know

Whatever choice you make
Pls think of the kids and not yourself, your wwoman or the love you share
Think of what will become of that child coming

Goodluck
Re: Marriage And The Genotype Question. by isblog(m): 9:34am On Oct 22, 2015
@ op, yeah it is obvious you two are in love but medically a 25% risk equates to MUCH, you wouldn't want to go through the experience of nurturing sicklers, it is "everything consuming..
Yes medically genotype of would be babies could be determined, but note that the procedures are expensive too and you never can tell how many T.O.Ps you may have to do till you get the child/children with the desired genotype.

It is quite tough for two love birds to walk away and so we often times bring in our faith to work here.. I know people who have been through same and all children free from the SS genotype, more of carriers and AA, so it is possible...

In all my talk, If I was in these shoes, me and my lady will have to come to terms with walking away peacefully for the greater good... Tough but worth it
Re: Marriage And The Genotype Question. by donTbone(op): 9:39am On Oct 22, 2015
Dyt:
Its a tough decision
Don't let your case be like had I know

You can go for the options
I think sickle cell clinics offer that egg thing for 2m
Dunno about the tests but last I heard was like 750k
Choice is yours
Love they say conquers all but its not enough

I mother a warrior too
A young vibrant young man
I have been lucky all along
Maybe God is giving me that grace only cos I didn't know

Whatever choice you make
Pls think of the kids and not yourself, your wwoman or the love you share
Think of what will become of that child coming

Goodluck
Thanx ma! I love her, no doubt! and am an advocacy of 'while in love, use your brain'.
But at this, am seriously down..she was sad when she heard at first.
I dnt just see my self starting to approach a lady for relationship, thou we are yet to start this!

But,am sorry ma, in your own case, did you went for a test before you married and how
did u managed caring for your strong warrior?
Re: Marriage And The Genotype Question. by Dyt(f): 9:50am On Oct 22, 2015
donTbone:
Thanx ma! I love her, no doubt! and am an advocacy of 'while in love, use your brain'.
But at this, am seriously down..she was sad when she heard at first.
I dnt just see my self starting to approach a lady for relationship, thou we are yet to start this!

But,am sorry ma, in your own case, did you went for a test before you married and how
did u managed caring for your strong warrior?
We did several tests
I mean lots
We were high school lovers
So at the beginning to the decision time
We had
But can't say where it all came from
My results always shown AS while his AA
What went wrong I dunno
Finding out about my lil man caused lots of havoc

Serious ones
That we all had to go and then wow
He's actually AS
cry cry cry

What could I have done
And only found out when lil man was almost 2
And then he started reacting to things
But with best of care
He's never been admitted nor drips
He takes his drugs
Eats good food

He's very playful
Stubborn
Sweet
Talkative
Intact you will so doubt it
He's full of life
Re: Marriage And The Genotype Question. by Nobody: 10:00am On Oct 22, 2015
Op, please advice yourself. 25% is too much risk. You don't want your ignorance to make your child/ren suffer. Forget love cos Sometimes love won't be enough. Seeing your child/ren go thru crises and not being able to help them might diminish love..
Re: Marriage And The Genotype Question. by donTbone(op): 10:13am On Oct 22, 2015
Dyt:
We did several tests
I mean lots
We were high school lovers
So at the beginning to the decision time
We had
But can't say where it all came from
My results always shown AS while his AA
What went wrong I dunno
Finding out about my lil man caused lots of havoc

Serious ones
That we all had to go and then wow
He's actually AS
cry cry cry

What could I have done
And only found out when lil man was almost 2
And then he started reacting to things
But with best of care
He's never been admitted nor drips
He takes his drugs
Eats good food

He's very playful
Stubborn
Sweet
Talkative
Intact you will so doubt it
He's full of life
Hmmmmm... how I wish I could meet the lil boy! sad
Thanx for the mature advice. God bless you ma!
Re: Marriage And The Genotype Question. by egbaguy: 10:59am On Oct 22, 2015
Dyt:
We did several tests I mean lots We were high school lovers So at the beginning to the decision time We had But can't say where it all came from My results always shown AS while his AA What went wrong I dunno Finding out about my lil man caused lots of havoc
Serious ones That we all had to go and then wow He's actually AS cry cry cry
What could I have done And only found out when lil man was almost 2 And then he started reacting to things But with best of care He's never been admitted nor drips He takes his drugs Eats good food
He's very playful Stubborn Sweet Talkative Intact you will so doubt it He's full of life
my lil angel has all these attributes also...... @dyt,u understand nah
Re: Marriage And The Genotype Question. by egbaguy: 11:08am On Oct 22, 2015
@OP.......I wnt even toe the 'sympathy' lane.....as we guys are bunch of MOFO.....yes,MOTHERFUCKER!!!!!!! What happens if u eventually out of stupidity get married to her and she starts having SS kids? Like we guys are,u'll leave her and marry anoda girl,right? If u av sense,u shudnt even be asking a stupid question like diz........I am AS mysef and av left ladies I love dearly cos of genotype issue....I am outta here!!!!!
Re: Marriage And The Genotype Question. by Dyt(f): 11:20am On Oct 22, 2015
donTbone:
Hmmmmm... how I wish I could meet the lil boy! sad
Thanx for the mature advice. God bless you ma!
Hehehehe
He's pretty a handful
Doubt if you can handle his sweet troubles


egbaguy:
my lil angel has all these attributes also...... @dyt,u understand nah
They are sweet
Sweetest of them all
Re: Marriage And The Genotype Question. by donTbone(op): 2:00pm On Oct 22, 2015
Dyt:
Hehehehe
He's pretty a handful
Doubt if you can handle his sweet troubles




They are sweet
Sweetest of them all
I love sweet stubbornness... av showcased some in the past too wink
Re: Marriage And The Genotype Question. by ugileo(m): 3:05pm On Oct 22, 2015
have never checked my genotype b4 always coming across AA buy recently fell in love (real love) with a gal who is As, so decided to go 4 my own test, only to realised that am AC, still cant come in terms with this. i believe there is a way out. somebody please tell me this way out (not having Sc children)
Re: Marriage And The Genotype Question. by jackpot(f): 7:34pm On Oct 22, 2015
@ugileo
run as fast as your legs can carry you.
Re: Marriage And The Genotype Question. by donTbone(op): 9:17am On Oct 26, 2015
ugileo:
have never checked my genotype b4 always coming across AA buy recently fell in love (real love) with a gal who is As, so decided to go 4 my own test, only to realised that am AC, still cant come in terms with this. i believe there is a way out. somebody please tell me this way out (not having Sc children)
That was wah happened to me likewise. Funny enough, I wanted to tell an uncle abt it just to hear my uncle discuss it as stupid and insane for such to av happened between couples. I had no option than to kip my peace sad
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