American and Chinese scientists have found that an antimicrobial ingredient commonly used in hand soaps and toothpastes could have adverse effects on colonic inflammation and colon cancer by altering gut microbiota, the microbes found in people’s intestines.

A study published in the journal Science Translational Medicine revealed that short-time treatment with low-dose triclosan led to low-grade colonic inflammation, and exaggerated disease development of colitis and colitis-associated colon cancer in mice.

“These results, for the first time, suggest that triclosan could have adverse effects on gut health,” said Zhang Guodong, assistant professor of food science at the University of Massachusetts Amherst, the paper’s senior author.

Zhang told Xinhua, “The toothpaste we use can enter into the intestinal tract, then impacting the gut microbiota.”

Triclosan is among the most widely used antimicrobial ingredients and is found in more than 2,000 consumer products and a National Health and Nutrition Examination survey showed that triclosan was detected in about 75 per cent of the urine samples of individuals tested in the U.S. and it is among the top ten pollutants found in U.S. rivers.

“Because this compound is so widely used, our study suggests that there is an urgent need to further evaluate the impact of triclosan exposure on gut health in preparation for the potential establishment of further regulatory policies,” said Yang Caixia, a postdoctoral fellow in Zhang’s laboratory and the paper’s first author.

Zhang’s team and Chinese researchers including those from Xi’an Jiaotong University investigated the effects of triclosan on colonic inflammation and colon cancer using several mouse models.

They reported that in all mouse models tested, triclosan promoted colonic inflammation and colon tumorigenesis.

The research team found that gut microbiota was critical for the observed adverse effects of triclosan, since feeding triclosan to mice reduced the diversity and changed the composition of the gut microbiome.

However, triclosan had no effect in a germ-free mouse model where there is no gut microbiome present, nor in a genetically engineered mouse model where there is no Toll-like receptor 4 (TLR4), an important mediator for host-microbiota communications.

“This is strong evidence that gut microbiota is required for the biological effects of triclosan,” Zhang said.

This study observed that triclosan altered mouse gut microbiota, increased inflammation, increased the severity of colitis symptoms and spurred colitis-associated colon cancer cell growth.

http://www.akelicious.net/2018/05/see-how-toothpastes-cause-health-problem.html

Everyday these guys must come up with something we should or shouldn't do in other to stay healthy
Our forefathers didn't heard all these yet they were healthier and stronger

Nothing wey no be problem for this life...


Odiegwu oh...

Kuku kill us

op, was a solution/alternative not provided?


chai, i no fit brush teeth in peace again.

Josh44s:
Am tired

Me too

Make we kuku dey carry smelly mouth up and down

Nothing man no go hear Finish.

I thought Brushing Morning and Night is good for the Health

IN addition, i believe you can do a proper brushing without a Toothpaste,

Now, Toothpaste don dey cause health problem,

Maybe make we Kuku dey carry our mouth oozing UPANDAN.

Just say make we no brush teeth again..... Going back to my "local chewing stick", pako, dogoyaro....

Thank God I don't brush with toothpaste

this one gidi gan o

Maybe it's time to go back to the era of chewing stick if that's what they're driving at but finds difficult to spill it out.
There's nothing these guys won't find fault with, even excess intake of water they already condemned.

As if living ain't risky enough. Na them sabi.

Una dey mad.
Everyday new stupid research.

Toothpastes again?!
Something must kill a man

It's time to return to our beloved and trusted chewing stick aka PAKO

I no brush again.

No beg me oh

Na to use eggshell take brush teeth.. Or vim sef

Josh44s:
Am tired. So we can not brush our teeth again. Am just tired abeg.

Which cain wahalah be this, How can we avoid toothpaste now...maybe we need to go back to our chewing stick jejely.

Oma WA GA oh.. Wetin we go come dey use like this..

Am not surprise sha anything chemical must have adverse effects no matter how nice n effective it is,its time to go back to our pako

Small una go say make we no wear cloth again

i have been using chewing stick for a while now and I find it very convenient. i rather have brown teeth and stay alive than use paste and die

Una say what American and Chinese scientists have found that an antimicrobial ingredient commonly used in hand soaps and toothpastes could have adverse effects on colonic inflammation and colon cancer by altering gut microbiota, the microbes found in people’s intestines

use pako to brush ur teeth. is healthy and natural. (chewing stick.) very OK and no side effect. stop all dis chemical of A thing oyinbo dey give u. stick to ur own root.

Okwyla:
American and Chinese scientists have found that an antimicrobial ingredient commonly used in hand soaps and toothpastes could have adverse effects on colonic inflammation and colon cancer by altering gut microbiota, the microbes found in people’s intestines.

A study published in the journal Science Translational Medicine revealed that short-time treatment with low-dose triclosan led to low-grade colonic inflammation, and exaggerated disease development of colitis and colitis-associated colon cancer in mice.

“These results, for the first time, suggest that triclosan could have adverse effects on gut health,” said Zhang Guodong, assistant professor of food science at the University of Massachusetts Amherst, the paper’s senior author.

Zhang told Xinhua, “The toothpaste we use can enter into the intestinal tract, then impacting the gut microbiota.”

Triclosan is among the most widely used antimicrobial ingredients and is found in more than 2,000 consumer products and a National Health and Nutrition Examination survey showed that triclosan was detected in about 75 per cent of the urine samples of individuals tested in the U.S. and it is among the top ten pollutants found in U.S. rivers.

“Because this compound is so widely used, our study suggests that there is an urgent need to further evaluate the impact of triclosan exposure on gut health in preparation for the potential establishment of further regulatory policies,” said Yang Caixia, a postdoctoral fellow in Zhang’s laboratory and the paper’s first author.

Zhang’s team and Chinese researchers including those from Xi’an Jiaotong University investigated the effects of triclosan on colonic inflammation and colon cancer using several mouse models.

They reported that in all mouse models tested, triclosan promoted colonic inflammation and colon tumorigenesis.

The research team found that gut microbiota was critical for the observed adverse effects of triclosan, since feeding triclosan to mice reduced the diversity and changed the composition of the gut microbiome.

However, triclosan had no effect in a germ-free mouse model where there is no gut microbiome present, nor in a genetically engineered mouse model where there is no Toll-like receptor 4 (TLR4), an important mediator for host-microbiota communications.

“This is strong evidence that gut microbiota is required for the biological effects of triclosan,” Zhang said.

This study observed that triclosan altered mouse gut microbiota, increased inflammation, increased the severity of colitis symptoms and spurred colitis-associated colon cancer cell growth.

http://www.akelicious.net/2018/05/see-how-toothpastes-cause-health-problem.html

na to return to pako ( local chewing stick) last last

Chewing stick must take over.