₦airaland Forum

Nonapeptide-1 can prevent melanin synthesis and unwanted pigmentation by preventing activation of the tyrosinase, thus allowing for a better control over skin tone.

Carbetocin Acetate (trade name Duratocin) is an eight amino acid long analogue of oxytocin (a nonapeptide) with improved in vivo stability over oxytocin. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.

Bremelanotide, formerly known as PT-141, is a peptide drug. Similarly to its analogues α-MSH and melanotan II, bremelanotide acts as a non-selective agonist of all of the melanocortin receptors except MC2.

Chelate peptide is an organic compound and commonly used as a complexing agent, which have been widely used as contrast agents for cancer treatments. It can also be linked to molecules that have affinity to various structures (e.g. somatostatin receptors on neuroendocrine tumours). The generated compounds may combine with a number of radioisotopes to be used in cancer therapy and diagnosis. For example, DOTA could act as a chelator for a radionuclide. (Tyr3)-octreotate, a derivative of octreotide, can bind to somatostatin receptors that are found on the cell surfaces of a number of neuroendocrine tumours. Therefore, DOTA-(Tyr3)-Octreotate is able to direct the radioactivity into the tumour.

Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide, is an inhibiting hormone of the secretin family of hormones. GIP, along with glucagon-like peptide-1 (GLP-1), belongs to a class of molecules referred to as incretins.

Octreotide is a longer acting synthetic octapeptide analog of naturally occurring somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormone.

Deslorelin Acetate (brand name Ovuplant) is currently approved for use in veterinary medicine and is used to induce ovulation in mares as part of the artificial insemination process. It is also used to stabilize high-risk pregnancies, mainly of livestock.

Acetyl Glutamyl Heptapeptide-3 or Acetyl Octapeptide-1 (or -3) (SNAP- is scientifically and reasonablely designed of anti-wrinkle active ingredients of polypeptide. It has a similar role to Areginine Essence and has become one of the most popular raw materials around the world for upscale anti-wrinkle cosmetics.

Growth hormone releasing hormone (GHRH) is a releasing hormone of growth hormone (GH). It is a 44-amino acid peptide hormone produced in the arcuate nucleus of the hypothalamus. GHRH is released from neurosecretory nerve terminals of these arcuate neurons, and is carried by the hypothalamo-hypophyseal portal system to the anterior pituitary gland, where it stimulates growth hormone (GH) secretion by stimulating the growth hormone-releasing hormone receptor. GHRH is released in a pulsatile manner, stimulating similar pulsatile release of GH.

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