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FactorVIII's Posts

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PoliticsRe: Meet The Female Dj That Performed At Buhari's Inauguration Gala Night by FactorVIII: 12:50pm On May 30, 2015
..there you go

PoliticsRe: Comedian Wale Gate's Oshiomhole Tweet Sets Twitter On Fire by FactorVIII: 10:23pm On May 15, 2015
He was looking for attention, He got it.
HealthRe: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by FactorVIII: 2:32pm On May 12, 2015
tunergy:
IWE! IWE!! IWE!!! (BOOK! BOOK!! BOOK!!!)

CAN YOU TRANSALATE TO ENGLISH PLEASE.
1. it is very possible, wad used as a case study in one of my classes here in LUTH
2. the fact that one is 'AA' doesn't mean there isnt a gene deletion somewhere in the globin chain . (hemoglobin is made up of globin and heme )
3.such deletion is transmissible and if it combines with HB S (which in this case is from the mother ) , will result in sickling
4. when tests (hb electrophoresis, sickling test )are carried out on the man, they will appear normal as it takes DNA analysis to detect the deletion
5. almost certain this is what happened as a paternity test ruled out infidelity
6 . hope I am clearer.
HealthRe: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by FactorVIII: 1:52pm On May 12, 2015
Demichaels:
My friend's 10 year Marriage is about to collapse.

His, my friend's genotype is AA and his wife's genotype is AS but their 4 year old daughter has been confirmed to have SS genotype by not less than 4 different medical experts. He confronted the wife and accused her of infidelity but she vehemently denied having any affair with another man. In other to prove her wrong, my friend subjected the little girl to a paternity test and there he got the shock of his life - the result showed he actually is the father of the girl. At first he accused the doctor of compromise because he is their family doctor and somehow relates to the wife. He then decided to go to another hospital to prove the paternity of the girl child there and then he got another shocker - the first result was actually correct. As It stands, my friend has consulted more than five other doctors outside the state of his residence and all Confirmed that the girl's genotype is SS and he actually is the father of the child despite his and the wife's genotype being as stated above. Even the doctor's are confused by the results as it negate conventional medical norm.

My question now is, experts in the house, is there anything that can lead to such unconventional biological flaw? Under what condition can AS and AA couple have an SS child? Can mutation lead to such condition? My friend insists on divorce because he doesn't believe the wife. Should he go ahead based on what we all know about genotype?


Please I need matured advice on this. This is a REAL LIFE SITUATION AND NO FICTION. I WOULD HAVE MENTIONED NAMES AND ADDRESS OF THE COUPLE BUT I DON'T HAVE THEIR PERMISSION YET. THIS IS HAPPENING RIGHT HERE IN PORT HARCOURT OLD GRA WE'RE LIVING
1. @Demichaels pls tell your friend to ask his
doctor to check him for alpha thalassemia
2. I am almost certain he has that.
3. alpha + thalassemia is usually harmless, it is
caused by alpha gene deletions or in some
cases dysfunctional alpha gene. However,
people (the child in this case ) who inherit
combinations of hb S (ie from the mother in this
case ) may have hemoglobin disorder.
4. Hemoglobin electrophoresis is normal, DNA
analysis is needed to be certain
5. Since a paternity test has been done here,
infidelity resulting to the birth of the child can
be safely ruled out.
6. This is simple Hematology.
7. Pls go to Hematology department LUTH to
confirm, you will meet my professors and
doctors, they are nice people
8. @ some nairaland peeps. pls if you are not
enlightened on a particular subject, pls read abt
it instead of judging people and using words
like "impossible"
9. I really hope you see this. it can save your
friend's marriage.
HealthRe: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by FactorVIII: 1:42pm On May 12, 2015
1. @Demichaels pls tell your friend to ask his doctor to check him for alpha thalassemia
2. I am almost certain he has that.
3. alpha + thalassemia is usually harmless, it is caused by alpha gene deletions or in some cases dysfunctional alpha gene. However, people (the child in this case ) who inherit combinations of hb S (ie from the mother in this case ) may have hemoglobin disorder.
4. Hemoglobin electrophoresis is normal, DNA analysis is needed to be certain
5. Since a paternity test has been done here, infidelity resulting to the birth of the child can be safely ruled out.
6. This is simple Hematology.
7. Pls go to Hematology department LUTH to confirm, you will meet my professors and doctors, they are nice people
8. @ some nairaland peeps. pls if you are not enlightened on a particular subject, pls read abt it instead of judging people and using words like "impossible"
9. I really hope you see this. it can save your friend's marriage.
CelebritiesRe: Seyi Shay Wore A Crazy See-Through Outfit To Channel O Awards by FactorVIII: 11:14pm On Dec 02, 2014
don't be surprised if its 3Million Naira
HealthRe: New Outbreak Of Lassa Fever In Oyo State by FactorVIII: 10:16pm On Oct 25, 2014
All these haemorrhagic fevers be having a field day. We have Ribavarin though unlike Ebola
PoliticsRe: No Governor Can Take Credit For Wining Ebola War – Jonathan by FactorVIII: 4:16am On Oct 17, 2014
WIZGUY69:
[size=48]credit should be given to the governors of the states that curb Ebola. I disagree with jona. on this.[/size]
Ebola in Lagos was curbed mainly by the efforts of 'Community Health Department, College of Medicine of the University of Lagos' ..that is a federal institution.
The virus Sample was confirmed at the Chevron
research Laboratory at LUTH by Professor Omilabu (my lecturer)...another Federal institution.
Lagos State played her part but it was more of a Federal thing.
PoliticsRe: Armed Thugs Invade Edo State House Of Assembly Quarters (pics) by FactorVIII: 7:07pm On Oct 11, 2014
That bullet proof door actually works...
PoliticsRe: Observation: APC Has Paid Agents On Nairaland! by FactorVIII: 6:46pm On Oct 10, 2014
berem:
1000likes!
"grin fact that I
voice my opinions does not mean I'm been
paid to do so. I post what I believe in"
Can the same be said about you
Music/RadioRe: I Wrote A Song For Rihanna – Wizkid by FactorVIII: 6:21pm On Oct 10, 2014
Its a norm in the music industry especially when artistes are working on their albums.
Lots of songs are usually submitted by other artistes/songwriters, then the final selection is then made. your song may or may not make the list.
pretty sure lots of peeps don't know Rihanna "Diamonds" was written by Sia.
PoliticsRe: Deplorable State Of Meiran Road, Lagos by FactorVIII(op): 6:17am On Oct 07, 2014
....

PoliticsDeplorable State Of Meiran Road, Lagos by FactorVIII(op): 6:16am On Oct 07, 2014
This is to bring to the notice of the appropriate authorities, the state of the above named stretch of road.
Construction has been ongoing for over two (2) years and the quality of work done to say the least is totally depressing.
Work has not been done for several months now and the project seems to be an abandoned one.
I will be posting pictures to support my complaint.
PS. Meiran will be grateful if she can get a good road. A concerned Meiran resident.

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