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Immune system breakthrough wins Nobel medicine prize for US, Japan scientists

STOCKHOLM, Oct 6 (Reuters) - American scientists Mary Brunkow and Fred Ramsdell and Shimon Sakaguchi from Japan won the 2025 Nobel Prize in Physiology or Medicine on Monday for work shedding light on how the immune system spares healthy cells, creating openings for possible new autoimmune disease and cancer treatments.

Their discoveries relate to peripheral immune tolerance, or "how we keep our immune system under control so we can fight all imaginable microbes and still avoid autoimmune disease", said Marie Wahren-Herlenius, a rheumatology professor at Sweden's Karolinska Institute, the awarding body.

The institute said all three laureates brought to the fore so-called regulatory T cells, a class of white blood cells that act as the immune system's security guards that keep immune cells from attacking our own body.

RESEARCH INTO WHAT STOPS IMMUNE SYSTEM ATTACKING ITSELF

Brunkow, who found out she had won after being woken by her dog barking at a news photographer on the front porch of her Seattle home, said she, Ramsdell and their colleagues had isolated a gene called FOXP3 that could be used as a marker for the cells.

"They're rare, but powerful, and they're critical for sort of dampening an immune response," she said in an interview, describing the cells as a braking system that prevents the body's immune system from tipping over into attacking itself.

https://www.reuters.com/business/healthcare-pharmaceuticals/brunkow-ramsdell-sakaguchi-win-2025-nobel-medicine-prize-2025-10-06/

Very interesting research that can be used to.for example fight autoimmune diseases . Even infections

A well deserved Nobel

knowledge is always power, I ll keep saying it scientific breakthroughs remain the fulcrum for human existence.

Congratulations to the new nobel laureates. I will surely win this price one day, I am working towards it.

Congratulations to them all maybe Trump would win the Noble price for PEACE

Putin is most qualified for this particular award this year.
Developing a cure for HIV/AIDS is no small feat but hypocrites and bootlickers won't see the novelty because they are sentimentally brainwashed by the real terrorists of the world's peace

Great work but I think the Chinese that found a way to mend broken bone with gel deserves it .

Great and congratulations to them,one day we will also be honored .

Congratulations to them. And they have a very good working system and gives in their respective countries.

Their countries are not kwantiries...they don't have area boys and agberoes harassing everyone and determining who becomes this and that.

KayB:
Putin is most qualified for thus particular award this year.
Developing a cure for HIV/AIDS is no small feat but hypocrites and bootlickers won't see the novelty because are sentimentally brainwashed by the real terrorists of the world's peace

How ? Is Putin a scientist ? How did he develope a cure for HIV AIDS? What is the name of the drugs .

Sabadon:
knowledge is always power, I ll keep saying it scientific breakthroughs remain the fulcrum for human existence.

And human destruction eg Atomic,Hydrogen and Nuclear Bombs. Sometimes I wonder, why do we create these destructive things?

KayB:
Putin is most qualified for thus particular award this year.
Developing a cure for HIV/AIDS is no small feat but hypocrites and bootlickers won't see the novelty because are sentimentally brainwashed by the real terrorists of the world's peace

Lol you don test the Cure....


Cause apart from Gas wey Russia dey always shout have never seen anything Russia made...


And if anybody is to be awarded for that...


That will be the scientist that roll it out I don't know when Puttin turn to Scientist...

Congrats to them.... I think Elon musk and his team might win one in d long run... They are currently working on visual impairment... If successful I think he deserves one....

A whole lot goes to research in US .
ChatGPT , AI also remains one of the greatest innovations in the last few years .

Congratulations to them all
This is where government works
Good countries where excellence is rewarded.
Just imagine a country where touts and agberos have been institunalized. Some1 like MC oluomo and Sego would be threatening citizens on election. What do we expect then?

Where are those US haters who said US is going behind China and Russia. Where is that writerng of sa to come defend this another US feat in advancement.

No country on earth come close to the US in tech and medicine advancement

OriOko88:
Where are those US haters who said US is going behind China and Russia. [b]Where is that writerng [/b]of sa to come defend this another US feat in advancement.

No country on earth come close to the US in tech and medicine advancement

He is the one that quoted up there that put in deserves it more for HIV cure. Very delusional

Very good job. Immunology is not easy. Very tricky, compared to physiology, anatomy, and microbiology.

Understanding it, alongside molecular genetics, pharmacology and biochemistry are vital to human health.

HydraFeeds:
Great work but I think the Chinese that found a way to mend broken bone with gel deserves it .

Wow, i am just hearing or reading this for the first time. Great things are happening in the scientific world.

I thought they were Ibo

Wanted to say
Now we can breathe

nairalanda1:
Very interesting research that can be used to.for example fight autoimmune diseases . Even infections

A well deserved Nobel

Better Nobel Laureates. Not the type awarded to one fella that writes children's story book.

This is a placr where you’ll never see Muslims. Anything that has got to with high level intellect no be for them..
While others are thinking of how to advance the human race through science and tech, they’ll be busy thinking of how to kpai Jews, how to protest or how to have sex and make as much baby as possible for their so called global takeover.