Okay, I'm really getting confused trying to understand these two pathological pain conditions, Central Pain and Neuropathic Pain. My questions are:

What are the differences between these conditions?
Are there any similarities between its pathological conditions.?
What about its manifestations, are they similar as well or they have their differences?

Please any information on these questions will surely help, perhaps links. Thanks.

i hope this helps.

Neuropathic pain is initiated or caused by a primary lesion or
dysfunction in the nervous system. Neuropathic pain is
composed of peripheral neuropathic pain (with a primary lesion or
dysfunction in the peripheral nervous system) and central
neuropathic pain (CNP; with a primary lesion or dysfunction in the
central nervous system). CNP may be further subdivided into
supraspinal central neuropathic pain and spinal central neuropathic
pain. Opioids have a role in the pharmacologic management of
neuropathic pain; however, there is a scarcity of literature on the
treatment of CNP with opioids. One of the few statements in the
literature regarding the analgesic efficacy of opioids for CNP
suggests that despite limited data, the opioid responsiveness for
neuropathic pain of central and peripheral etiologies is similar.
After reviewing the extremely limited data, it is proposed that
although there may be a subpopulation of patients with CNP who
have a reasonable analgesic response to opioids, overall, when
sensory pain rating is used as the yardstick, CNP appears to
respond less well to opioids than peripheral neuropathic pain.
Thus, opioids should be considered a second- or third-line agent
in any algorithm of the pharmacologic treatment of CNP. Also
within CAP, it appears that supraspinal central neuropathic pain
may respond less well to a trial of opioids than spinal central
neuropathic pain. Moreover, under close monitoring for side
effects (eg, constipation), it is suggested that clinicians may want
to consider titrating to higher doses of potent opioids before the
trial is judged to be unsuccessful for refractory supraspinal central
neuropathic pain.

Peterken05:
i hope this helps.

Neuropathic pain is initiated or caused by a primary lesion or
dysfunction in the nervous system. Neuropathic pain is
composed of peripheral neuropathic pain (with a primary lesion or
dysfunction in the peripheral nervous system) and central
neuropathic pain (CNP; with a primary lesion or dysfunction in the
central nervous system). CNP may be further subdivided into
supraspinal central neuropathic pain and spinal central neuropathic
pain. Opioids have a role in the pharmacologic management of
neuropathic pain; however, there is a scarcity of literature on the
treatment of CNP with opioids. One of the few statements in the
literature regarding the analgesic efficacy of opioids for CNP
suggests that despite limited data, the opioid responsiveness for
neuropathic pain of central and peripheral etiologies is similar.
After reviewing the extremely limited data, it is proposed that
although there may be a subpopulation of patients with CNP who
have a reasonable analgesic response to opioids, overall, when
sensory pain rating is used as the yardstick, CNP appears to
respond less well to opioids than peripheral neuropathic pain.
Thus, opioids should be considered a second- or third-line agent
in any algorithm of the pharmacologic treatment of CNP. Also
within CAP, it appears that supraspinal central neuropathic pain
may respond less well to a trial of opioids than spinal central
neuropathic pain. Moreover, under close monitoring for side
effects (eg, constipation), it is suggested that clinicians may want
to consider titrating to higher doses of potent opioids before the
trial is judged to be unsuccessful for refractory supraspinal central
neuropathic pain.

Thanks a lot bro, was away for a while due to my health. It helped btw.

soicyboi1:
Thanks a lot bro, was away for a while due to my health. It helped btw.

you welcome, how you feeling now?

Peterken05:
you welcome, how you feeling now?

Much better, thanks for your concern