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Lassa Fever–signs/symptoms, Causes, Diagnosis, Prevention, Treatment, Prognosis / Lassa Fever Kills Two In Asaba FMC / Lassa Fever: Signs, Symptoms, Treatment & Prevention (2) (3) (4)
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Lassa Fever-signs And Symptoms. by Sanni45(m): 9:50pm On Jan 16, 2016 |
Signs and symptoms of Lassa fever
typically occur 1-3 weeks after the
patient comes into contact with the
virus. For the majority of Lassa fever
virus infections (approximately 80%),
symptoms are mild and are
undiagnosed. Mild symptoms include
slight fever, general malaise and
weakness, and headache. In 20% of
infected individuals, however, disease
may progress to more serious
symptoms including hemorrhaging (in
gums, eyes, or nose, as examples),
respiratory distress, repeated vomiting,
facial swelling, pain in the chest, back,
and abdomen, and shock. Neurological
problems have also been described,
including hearing loss, tremors, and
encephalitis. Death may occur within
two weeks after symptom onset due to
multi-organ failure.
The most common complication of
Lassa fever is deafness. Various
degrees of deafness occur in
approximately one-third of infections,
and in many cases hearing loss is
permanent. As far as is known, severity
of the disease does not affect this
complication: deafness may develop in
mild as well as in severe cases.
Approximately 15%-20% of patients
hospitalized for Lassa fever die from the
illness. However, only 1% of all Lassa
virus infections result in death. The
death rates for women in the third
trimester of pregnancy are particularly
high. Spontaneous abortion is a serious
complication of infection with an
estimated 95% mortality in fetuses of
infected pregnant mothers.
Because the symptoms of Lassa fever
are so varied and nonspecific, clinical
diagnosis is often difficult. Lassa fever
is also associated with occasional
epidemics, during which the case-
fatality rate can reach 50% in
hospitalized patients. |
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