What is Cholesterol?
Cholesterol is a waxy substance made by the liver and also acquired through diet. It is found in the blood and in all cells in the body. The body uses cholesterol to produce bile, some hormones, vitamin D, cell membranes, and myelin (the material that surrounds nerves). A high level of cholesterol in the blood is called hypercholesterolemia. High levels of blood cholesterol have been linked to heart disease.

Description
Cholesterol in small quantities is necessary for the body to function properly, but the liver is able to synthesize about 1,000 mg of cholesterol a day, which is all the body needs. However, because cholesterol is found in animal products- meat, fish, shellfish, egg yolks, and dairy products-people also get cholesterol through their diet, and too much cholesterol can be harmful. Cholesterol does not dissolve in blood. Instead it moves through the circulatory system in combination with carrier substances called lipoproteins. There are two carrier-cholesterol combinations, low-density lipoprotein (LDL) or "bad" cholesterol and high-density lipoprotein or "good" cholesterol.

Why Is Cholesterol Important?
Your blood cholesterol level has a lot to do with your chances of getting heart disease. High blood cholesterol is one of the major risk factors for heart disease. A risk factor is a condition that increases your chance of getting a disease. In fact, the higher your blood cholesterol level, the greater your risk for developing heart disease or having a heart attack. Heart disease is the number one killer of women and men in the world. Each year, millions of people have heart attacks, and about a half million people die from this heart disease.

How Does Cholesterol Cause Heart Disease?
When there is too much cholesterol (a fat-like substance) in your blood, it builds up in the walls of your arteries. Over time, this buildup causes "hardening of the arteries" so that arteries become narrowed and blood flow to the heart is slowed down or blocked. The blood carries oxygen to the heart, and if enough blood and oxygen cannot reach your heart, you may suffer chest pain. If the blood supply to a portion of the heart is completely cut off by a blockage, the result is a heart attack.

High blood cholesterol itself does not cause symptoms, so many people are unaware that their cholesterol level is too high. It is important to find out what your cholesterol numbers are because lowering cholesterol levels that are too high lessens the risk for developing heart disease and reduces the chance of a heart attack or dying of heart disease, even if you already have it. Cholesterol lowering is important for everyone--younger, middle age, and older adults; women and men; and people with or without heart disease.

What Affects Cholesterol Levels?
A variety of things can affect cholesterol levels. These are things you can do something about:

DIET- Saturated fat and cholesterol in the food you eat make your blood cholesterol level go up. Saturated fat is the main culprit, but cholesterol in foods also matters. Reducing the amount of saturated fat and cholesterol in your diet helps lower your blood cholesterol level.

WEIGHT- Being overweight is a risk factor for heart disease. It also tends to increase your cholesterol. Losing weight can help lower your LDL and total cholesterol levels, as well as raise your HDL and lower your triglyceride levels.

PHYSICAL ACTIVITIES- Not being physically active is a risk factor for heart disease. Regular physical activity can help lower LDL (bad) cholesterol and raise HDL (good) cholesterol levels. It also helps you lose weight. You should try to be physically active for 30 minutes on most, if not all, days.

Things you cannot do anything about also can affect cholesterol levels. These include:

AGE AND GENDER- As women and men get older, their cholesterol levels rise. Before the age of menopause, women have lower total cholesterol levels than men of the same age. After the age of menopause, women's LDL levels tend to rise.

HEREDITY- Your genes partly determine how much cholesterol your body makes. High blood cholesterol can run in families.

What Is Your Risk of Developing Heart Disease or Having a Heart Attack?

In general, the higher your LDL level and the more risk factors you have (other than LDL), the greater your chances of developing heart disease or having a heart attack. Some people are at high risk for a heart attack because they already have heart disease. Other people are at high risk for developing heart disease because they have diabetes (which is a strong risk factor) or a combination of risk factors for heart disease. Follow these steps to find out your risk for developing heart disease.

Step 1: Check the table below to see how many of the listed risk factors you have; these are the risk factors that affect your LDL goal.
Major Risk Factors That Affect Your LDL Goal

Cigarette smoking
High blood pressure (140/90 mmHg or higher or on blood pressure medication)
Low HDL cholesterol (less than 40 mg/dL)*
Family history of early heart disease (heart disease in father or brother before age 55; heart disease in mother or sister before age 65)
Age (men 45 years or older; women 55 years or older)

Even though obesity and physical inactivity are not counted in this list, they are conditions that need to be corrected.

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