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Nutritional modifications can reduce risk of developing cancer, there is a proven link between obesity and some types of cancer. Dietary energy density DED contributes to cancer risk. DED is a measure of food quality and the relationship of calories to nutrients. The more calories per gram of weight a food has, the higher its DED.

Whole foods like vegetables, nuts, seeds, fruits, lean protein, and beans are considered low-DED foods because they provide a lot of nutrients using very few calories. Processed foods like cake, burger and pizza are considered high-DED foods because you need to eat larger amount to get necessary nutrients. Regular consumption of foods high in DED contributes to weight gain in adults.

Women who consumed a diet higher in DED were ten percent more likely to develop an obesity-related cancer, independent of their body mass index.
Obese people may develop different kinds of cancer like oesophagus, kidney, bowel, breast and pancreas cancer.

Weight management alone may not be effective in preventing obesity-related cancers if a women eats diets high in energy density regularly. Higher DED in normal-weight women may cause metabolic dysregulation that is independent of body weight, which increase the cancer risk.
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