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Fertility clinics commonly use blood and urine tests to assess the quantity and quality of eggs remaining in a woman's ovaries, American Medical Association has found that these tests cannot predict whether a woman in her later reproductive years will get pregnant naturally. Women have more problems getting pregnant as they age. The egg supply reduces later in life, and the quality of the remaining eggs declines.

The age at which a woman can no longer conceive varies from person to person. About one-third of couples will have trouble getting pregnant if the wife is 35 years old or older, according to the American Society for Reproductive Medicine. Low levels of anti-mullerian hormone AMH and high levels of follicle-stimulating hormone FSH are indicators of low ovarian reserve, it means that a woman has fewer available eggs.

Researchers recruited women 30 to 44 years old with no known history or risk factors for infertility who were just starting to try to get pregnant. They took their blood and urine samples and followed them for a year to see whether the women will conceived.

As expected, AMH levels decreased and FSH levels increased with age. But after accounting for age, women with low ovarian reserve were just as likely to get pregnant as were those with normal values. Fertility tests are very good at predicting how many eggs a woman is going to make with injectable fertility drugs, but they cannot be recommended as a predictor of natural pregnancy.
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