Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 9/16/2016
Codeine phosphate is an opioid analgesic (pain reliever) drug used to treat many causes of mild to moderate pain. Codeine phosphate is available in generic form. Common side effects of codeine phosphate include:

drowsiness,
lightheadedness,
dizziness,
sedation,
shortness of breath,
nausea,
vomiting,
stomach pain,
sweating,
constipation,
itching, or
rash.
Serious side effects of codeine phosphate include:

dependence,
seizures,
confusion,
near-fainting,
slow heart rate and
shallow breathing.
Codeine phosphate is available in strengths of 30 and 60mg tablets. Usual adult doses are15 to 60 mg every 4 to 6 hours (usual adult dose, 30 mg), while dosage for children (1 year and older) is weight-based (0.5mg/Kg) every 4 to 6 hours. Codeine sulfate may be expected to have additive effects when used in conjunction with alcohol, other opioids, or illicit drugs that cause central nervous system depression. There are no adequate and well-controlled studies in pregnant women. Codeine should be used during pregnancy only if the potential benefit justifies the potential risk. Codeine is secreted into human milk so benefits should outweigh risks to the breastfeeding infant. Codeine phosphate has been used in pediatric patients aged one year and above.

Our Codeine sulfate Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

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