A single dose of an anti-parasitic drug could essentially remove all genetic material of the COVID-19 virus within 48 hours, an Australian-led study has shown.

An anti-parasitic drug available throughout the world has been found to kill COVID-19 in the lab within 48 hours.

A Monash University-led study has shown a single dose of the drug Ivermectin could stop the SARS-CoV-2 virus growing in cell culture.

“We found that even a single dose could essentially remove all viral RNA (effectively removed all genetic material of the virus) by 48 hours and that even at 24 hours there was a really significant reduction in it,” Monash Biomedicine Discovery Institute’s Dr Kylie Wagstaff said on Friday.

While it’s not known how Ivermectin works on the virus, the drug likely stops the virus dampening the host cells’ ability to clear it.

The next step is for scientists to determine the correct human dosage, to make sure the level used in vitro is safe for humans.

“In times when we’re having a global pandemic and there isn’t an approved treatment, if we had a compound that was already available around the world then that might help people sooner,” Dr Wagstaff said.

“Realistically it’s going to be a while before a vaccine is broadly available.” Before Ivermectin can be used to combat coronavirus, funding is needed to get it to pre-clinical testing and clinical trials.

Ivermectin is an FDA-approved anti-parasitic drug also shown to be effective in vitro against viruses including HIV, dengue and influenza.

The study is the joint work of Monash Biomedicine Discovery Institute and the Peter Doherty Institute of Infection and Immunity.

The study findings have been published in Antiviral Research.

https://www.news.com.au/lifestyle/health/health-problems/coronavirus-australia-ivermectin-antiparasitic-drug-kills-covid19-in-lab/news-story/615c435e56aefc4b704f4fd890bd4c2c

Good news.

They should make it available fast.

One thing is sure.....Coronavirus virus must GO and people will go back to their normal activities.

But before then, pray and stay safe as instructed for you not to be a victim.

Study shows anti-parasitic drug ivermectin kills coronavirus within 48 hours



A collaborative study led by the Monash Biomedicine Discovery Institute (BDI) with the Peter Doherty Institute of Infection and Immunity (Doherty Institute), a joint venture of the University of Melbourne and Royal Melbourne Hospital, has shown that ivermectin, an anti-parasitic drug already available around the world, kills the coronavirus in cell culture within 48 hours.

Ivermectin, an FDA-approved anti-parasitic previously shown to have broad-spectrum anti-viral activity in vitro, is an inhibitor of the causative virus (SARS-CoV-2), with a single addition to Vero-hSLAM cells two hours post infection with SARS-CoV-2 able to effect ∼5000-fold reduction in viral RNA at 48 hours. The study concluded that ivermectin therefore warrants further investigation for possible benefits in humans.

Originally identified as an inhibitor of interaction between the human immunodeficiency virus-1 (HIV-1) integrase protein and the importin α/β1 heterodimer responsible for IN nuclear import, ivermectin has since been confirmed to inhibit IN nuclear import and HIV-1 replication.

Other actions of ivermectin have been reported, but ivermectin has been shown to inhibit nuclear import of host and viral proteins. It has been demonstrated to limit infection by RNA viruses such as DENV 1-4, West Nile Virus, Venezuelan equine encephalitis virus (VEEV) and influenza.

The results of this latest study demonstrate that ivermectin has antiviral action against the SARS-CoV-2 clinical isolate in vitro, with a single dose able to control viral replication within 24-48 hours.

The study authors stated: ‘Ultimately, development of an effective anti-viral for SARS-CoV-2, if given to patients early in infection, could help to limit the viral load, prevent severe disease progression and limit person-person transmission.’

https://pharmafield.co.uk/pharma_news/study_shows_anti-parasitic_drug_ivermectin_kills_coronavirus/

Ok Nigerians, over to you to buy all stocks available. Or maybe Trump should suggest it.

It will be good if Nigeria's Pharmacy researchers could work on effectiveness of the drug ivermectin on malaria virus. It is possible that one dose of ivermectin could kill all the malaria virus within 48 hours. After all, notwithstanding all the hype about coronavirus, malaria is still our greatest problem.