It was the Chinese philosopher Sun Tzu, and not Al Pacino in The Godfather Part 2, who first said, “Keep your friends close, and your enemies closer.” Yin Weidong, the CEO of Chinese biotech firm SinoVac, seems to have taken that advice to heart.


On the desk in his office in Beijing are two plastic models of a virus—each blue core surrounded by red protein spikes. From the time it started spreading in the central Chinese city of Wuhan in late December, containing that virus has occupied virtually every waking moment for the scientist.

The pandemic we now know as COVID-19 is rampaging across every continent. On the dozens of daily infection charts, broken down by nation and pasted floor to ceiling on Yin’s office wall, the numbers tell a horrifying story: 16 million infections and 640,000 deaths worldwide, including 146,000 American lives lost as of Monday.

But if the enemy is close, so is a possible new friend. Yin’s desk is now also home to several small glass vials of SinoVac’s COVID-19 vaccine—dubbed CoronaVac—that began phase 3 trials involving 9,000 volunteers in Brazil last week. (A phase 1 trial involves small groups of patients to check a vaccine for negative side effects, and a phase two trial usually tests for a combination of safety and efficacy, while a phase 3 trial is like a phase 2 but involving many more participants.)

“Looking at the data collected, I think we have more than an 80% chance of success,” says Yin.
Normally, getting from pathogen identification through phase 3 trials in about 10 years is considered quick. The mumps vaccine is generally considered the fastest ever developed at four years. But if all goes well, CoronaVac might be ready for regulatory approval early next year. Not that Yin is satisfied.

“Do you really think this is fast? Compared with the spread of the virus, it’s not fast enough,” he says, holding his plastic nemesis aloft with grudging respect. “That is how we should measure our progress.”

During the 2002 to 2003 SARS outbreak, which claimed over 774 lives worldwide, SinoVac was the only firm to go into phase 1 vaccine trials, but the pandemic suddenly disappeared. That meant that research was discontinued at a huge loss for the firm. It wasn’t entirely wasted, however. Now, 17 years later, SinoVac is able to build on that earlier work, given that COVID-19 is very similar to SARS. It and coronavirus are “like brothers,” says Yin.
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Source; https://ioalert.com

As damage control!

Another Covid 20