It is an aphorism that ignorance is not an excuse in law. It is a terrible thing to be without knowledge, especially the knowledge of God. He is the Giver of all knowledge. The Bible says, “The fear of the LORD is the beginning of wisdom...And by knowledge shall the chambers be filled with all precious and pleasant riches” (Proverbs 9:10, 24:4).

The passage today unveils sundry lessons. Prominent among them is the fact that it is damning for a person to be destitute of knowledge, particularly the knowledge of God. Without the right knowledge about our Creator, the Source of all good things, one will continue to wander in the direction of sin and perdition. The heart of such a person will reject God and His word, “Because the carnal mind is enmity against God...” (Romans 8:7).

https://www.thechristianfeeds.com/2021/09/daily-manna-devotional-knowledge-is.html