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When using Tramadol, it is important to take precautions to avoid potential side effects. The most common side effect of Tramadol is drowsiness, so it is important not to drink alcohol or take other medications that can cause drowsiness while taking Tramadol. It is also important to stay hydrated while taking Tramadol by drinking plenty of water. If you experience any other side effects, such as nausea, vomiting, or constipation, be sure to contact your doctor.