Zopiclone Zopisign 10 mg treats short-term insomnia. It diminishes nighttime waking and rest time. You should take this before going to sleep, preferably just before you go to bed. To keep the amount of medication consistent, it's recommended that you take it at the same time every day. Due to the habit-forming nature of this remedy, it should only be taken within the prescribed dosage and period. It may worsen your symptoms if you stop taking it suddenly without consulting your doctor.