₦airaland Forum

[quote author=fsb]@ Emmion

Sorry, its really been a long while since I read this thread, Its possible that your genotype has always been AC and that there were discrepancies with the second test results, One thing you must understand is that in terms of geographic distribution, the hemoglobin C allele is found at the highest frequencies in West Africa and it has been associated with protection against malaria.

A good number of people have the C allele but are unaware of it.

Also note that most people with the AC genotype show no symptoms,

About your financee who is also AC, well, if you put the stats together as I explained in my earlier posts:

For every child you'll have together, there is a 25% chance he/she will be AA, a 50% chance he/she will be AC and a 25% chance he/she would be CC.

Again, please don't think that CC and SS are the same. THEY ARE NOT, and that is in capital letters, Anyone who tells you so, doesn't know CRAP. Sickle Cell Dsx is a whole chapter on its own and writing about it will make this extremely lengthy,


@ mazaje

You can't even begin to compare the differences in severity between CC and SS disease,

Symptoms of Hemoglobin C dsx (CC)

Most people do not have symptoms. Occasionally, jaundice may occur.

Complications of Hemoglobin C dsx

Sometimes, they may experience the following:

Cholelithiasis (gall stones that may require treatment)
Splenomegaly (big spleen)
Angloid streaks (causing poor vision)
Aplastic crises (due to viral infection): episode of severe anemia

Treatment
There is no treatment. Folic acid supplementation is required to help the body with red blood cell production and improve symptoms of anemia.

Prognosis
Note that unlike the Hemoglobin S dsx (SS), pxts with Hemoglobin C dsx have a normal life expectancy,


Before I forget, what about SC genotype?

Please note the following:

AA: normal pxts
AS: don't show any symptoms
SS: sickle cell disease (sicklers)
AC: don't show any symptoms
CC: described above
SC? This condition is associated with recurrent anemia (breakdown of red cells in the blood vessels) and pain crises (vaso-occlusive crises). Some may also experience aseptic necrosis of the thigh bone (femur). Summary is that it is bad,

I do hope all the above helps,

Regards,
fsb,
[If a child is CC what can one do. Please help

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How much do you want to sell it last?