₦airaland Forum

Ondo Governor, Akeredolu Dies After Prolonged Battle With Leukemia

A family source told SaharaReporters on Wednesday that Akeredolu died in Germany.

SaharaReporters exclusively reported in January that Akeredolu was treating leukemia.

“The governor of Ondo State, Rotimi Akeredolu has leukemia, he is really down,” one of the sources in the Alagbaka Government House revealed at that time.

Leukemia is a cancer of the blood caused by a rise in the number of white blood cells in the body.

For sufferers, the white blood cells crowd out the red blood cells and platelets needed by the body to stay healthy.

White blood cells are potent infection fighters which grow and divide in an orderly way, as the body needs them. But in people with leukemia, the bone marrow produces an excessive amount of abnormal white blood cells, which don't function properly.

It is a cancer of blood-forming tissues that hinders the body’s ability to fight infections.

The types that exist include acute lymphoblastic leukemia, acute myeloid leukemia and chronic lymphocytic leukemia.

Treatment for leukemia can be complex depending on the type of leukemia and other factors.

However, some strategies and resources can help make treatment successful.

According to WebMD Cancer Center, its symptoms may include weakness or fatigue, bruising or bleeding easily, fever or chills, infections that are severe or keep coming back, and pain in your bones or joints.

Others may include headaches, vomiting, seizures, weight loss, night sweats, shortness of breath, and swollen lymph nodes or organs like the spleen.

Source: https://saharareporters.com/2023/12/27/breaking-ondo-governor-akeredolu-dies-after-prolonged-battle-leukemia?fbclid=IwAR0n2-XKc_3F_tJCP5jRHt4ZGkpgKMAfmHwOUM7qg2AUiSdCV6dToUOF-NE

What is leukemia? Learn about the types of leukemia, leukemia causes, common symptoms, and available treatments for the disease.

What Is Leukemia?
Leukemia is a broad term for blood cancers.1 The term applies to all types of leukemia, which include acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML).1 Leukemia begins in the soft, spongy tissue that makes up the center of most bones, called bone marrow. Bone marrow produces several types of blood cells, which perform different functions:

White blood cells, which fight infection
Red blood cells, which transfer oxygen from the lungs to the rest of the body
Platelets, which form clots that stop bleeding

In leukemia patients, the bone marrow produces large amounts of abnormal blood cells, which make it hard for healthy cells to do their important jobs. Over time, the cancerous cells can also spread to other organs and tissues throughout the body.1

Leukemia Prevalence
Approximately 472,714 Americans have leukemia.2 The American Cancer Society (ACS) predicts 60,650 new leukemia diagnoses in 2022 and roughly 24,000 deaths from the disease.3 Among adults in the U.S., leukemia is the eleventh most common cancer, accounting for 3.2% of all new cancer diagnoses and 3.9% of all cancer deaths.2 Leukemia generally affects more adults than children, with most diagnoses occurring between the ages of 65 and 74.2

Leukemia Prognosis
The prognosis for leukemia has improved dramatically in recent decades thanks to groundbreaking genetic research and new treatment options. On average, the overall five-year survival rate for adults with leukemia is more than 66%.4 The survival rates for specific types of leukemia are as follows:4

Acute lymphocytic leukemia (ALL): 72.1%
Acute myeloid leukemia (AML): 29.8%
Chronic lymphocytic leukemia (CLL): 88.6%
Chronic myeloid leukemia (CML): 71.7%

Causes and Risk Factors

What Causes Leukemia?
Leukemia is caused by genetic changes in bone marrow cells.

Scientists have yet to determine what causes the genetic changes in bone marrow cells that lead to leukemia. However, certain risk factors are associated with the disease. For example, risk of leukemia increases with age, and the disease is most common in people over 60 years old.

Leukemia and Genetics
The DNA inside of cells makes up a person’s genes, which control how those cells function. Genes called oncogenes help cells grow, divide, and stay alive while tumor suppressor genes control cell division and cause cells to die at the right time.

Cells multiply by dividing into two cells, making a new copy of the chromosomes (strands of DNA). Sometimes errors occur during this process that affect genes in the new chromosomes, which can turn on oncogenes or turn off tumor suppressor genes.

Several types of chromosome changes may contribute to leukemia and other types of cancer, including translocations—when DNA from one chromosome breaks off and becomes attached to a different chromosome, turning on oncogenes or turning off genes that would normally help a cell mature. For example, translocation of the so-called Philadelphia chromosome is present in ALL and CML. In this translocation, DNA is swapped between chromosomes 9 and 22.5,6

Other genetic mutations called deletions (the loss of part of a chromosome) might also cause certain types of leukemia. For example, people with CLL often have deletions in chromosomes 11, 13, and 17. Or they may have additions to chromosome 12.8

Not everyone with leukemia has the same genetic mutations even if they have the same type of leukemia. Some have multiple mutations, and others may have no known mutations.

There are very few links between heredity and leukemia. Certain genetic syndromes can increase the risk of developing ALL and AML, but most leukemias are caused by gene mutations acquired after birth.1,5, 9,10

Leukemia Risk Factors
Certain demographic and lifestyle factors can increase the risk of leukemia. There are also environmental risk factors for leukemia. These risks vary based on the type of leukemia:

Aging
Sex
Smoking
Benzene exposure
Treatment with chemotherapy drugs
Radiation exposure
Certain blood disorders
Having a genetic syndrome
Certain chromosomal abnormalities
Family history

Leukemia Prevention
There is currently no known way to prevent most types of leukemia, especially among children. You can reduce some acute leukemia risk factors by avoiding smoking and contact with benzene.13

Types of Leukemia
Leukemias are grouped into two categories: acute leukemia and chronic leukemia. The distinction is based on which blood cells are involved and how fast abnormal cells multiply.1 Acute leukemia develops and worsens quickly, while chronic leukemia develops slowly and worsens over time.1,13

Affected blood cells can either be lymphocytes (a type of white blood cell) or myeloid cells (immature cells that could develop into white or red blood cells or platelets). The type of leukemia a person has is determined in part by the affected cells: lymphocytes or myeloid cells.1

There are several different types of leukemia. Each has different treatment options and prognoses.


Acute Lymphocytic Leukemia (ALL)

Acute Myeloid Leukemia (AML)

Chronic Lymphocytic Leukemia (CLL)

Chronic Myeloid Leukemia (CML)

Chronic Myelomonocytic Leukemia (CMML)

Leukemia in Children

Also known as acute lymphoblastic leukemia, ALL progresses quickly and becomes fatal in just a few months if not treated.5 It begins in the bone marrow and affects white blood cells called lymphocytes—the main cells that comprise lymph nodes, a critical part of the immune system. There are two types of lymphocytes: B cells, which make antibodies to fight diseases, and T cells, which destroy germs and help regulate other immune system cells. B cell ALL begins in immature B cells, while T cell ALL can begin in T cells at any stage of maturity.14

ALL is uncommon, representing only about 0.5% of all cancers. ALL is most common in children younger than age 5, but ALL in adults is more fatal. Adults account for only 40% of ALL cases but 80% of deaths.15 Overall, the ACS predicts there will be 6,660 new cases of ALL in 2022 and 1,560 deaths.3

Leukemia Symptoms
Different types of leukemia cause many of the same symptoms, but some types of leukemia have specific symptoms and potential complications. Leukemia symptoms in adults and children may vary.

Signs of Leukemia in Adults
Acute leukemias cause many of the same symptoms. Abnormal cells crowd out healthy blood cells and may cause a person to experience:

Feeling fatigued, dizzy, lightheaded, or cold
Shortness of breath
Pale skin
Headaches
Recurring infections or difficulty recovering from infections
Bruises or tiny red or purple spots on the skin
Bleeding, including frequent or severe nosebleeds, bleeding gums, or heavy menstrual bleeding
Weight loss
Fever
Night sweats
Loss of appetite
Abdominal swelling or a feeling of fullness caused by an enlarged liver or spleen
Enlarged lymph nodes
Bone or joint pain

Chronic leukemias (CML, CLL, and CMML) can cause symptoms similar to those experienced with acute leukemias, but because these conditions develop much more slowly, people often experience no symptoms before a diagnosis. The most common sign of chronic leukemias is abnormal white or red blood cell counts.34,35,36 With CMML, extremely high monocyte levels show on blood tests. With CMML, monocytes can build up in the spleen or liver and enlarge these organs, causing a person to have abdominal pain or feel too full when eating.36

Signs of Leukemia in Children
The signs of leukemia in children are similar to those in adults.37 In rare cases, children might also experience seizures and vomiting.

In children, leukemia-like symptoms are more likely to be caused by other conditions. But it's important to have them seen by a doctor, who can perform blood tests to rule out leukemia or diagnose and treat it.

Leukemia Spots
Among the most visible signs of blood cancer are leukemia petechiae and leukemia purpura spots on the skin. Petechia are groups of pinpoint spots (smaller than 2 millimeters) that are nonblanching, meaning they do not disappear after applying brief pressure to the area. A purpura is a nonblanching spot larger than 2 millimeters. Both rashes are relatively common, especially in children, and they are a symptom of many different diseases and conditions, including enterovirus and meningitis.38

Leukemia Complications
In rare cases, leukemia can cause serious complications that require immediate medical attention. For example, T cell ALL can cause enlargement of the thymus, a small organ located behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus puts pressure on the trachea, which can cause trouble breathing or excessive coughing. It can also put pressure on the superior vena cava (SVC), a large vein that transports blood to the heart, causing blood to build up in the veins. This is a life-threatening condition called SVC syndrome, which can cause these symptoms:

Swelling in the neck, face, arms, and upper chest (sometimes with a bluish-red color)
Headaches
Dizziness
Loss of consciousness

With AML, cancer cells are larger than normal white blood cells and may clog blood vessels and cause a condition called leukostasis, a rare but life-threatening medical emergency that causes stroke-like symptoms.

Certain types of AML can also cause bleeding and clotting deficiencies, including dangerous blood clots that require immediate treatment.

Diagnosis and Treatment

Leukemia Diagnosis
Doctors will collect information and medical samples to diagnose leukemia and determine which type and stage of leukemia is present.

Leukemia Treatment
Leukemia treatment options vary based on the type of leukemia and how far it has spread. A doctor will also consider age, white blood cell count, and whether the patient was previously treated for cancer.45

Treatment options for leukemia include:

Conventional chemotherapy. Systemic treatment that travels throughout the body and kills cancer cells.
A bone marrow transplant. This procedure replaces faulty bone marrow stem cells with healthy ones.1,46
Radiation therapy. High doses of radiation attack and kill cancer cells.1,47
Immunotherapy. These drugs enable the immune system to better fight cancer.48
Splenectomy. The spleen is surgically removed.49
Targeted therapy. These drugs attack specific cancer cells.1

Global Impact of Leukemia
Worldwide, approximately 2.43 million people have leukemia.50 It is the 11th leading cause of cancer deaths, accounting for 3.2% of all new cancer cases and 3.9% of all cancer deaths.2 Because the disease is more common among older people, the burden of leukemia tends to be higher in developed countries than in developing middle- or low-income countries.51

Globally, leukemia places a large financial burden on individuals, families, insurers, and governments. In the U.S., for example, insurers spend an average of $200,000 to treat a person with chronic leukemia and $800,000 for a person with acute leukemia.52 A 2020 study estimated that the annual management cost for patients with for AML and myelodysplastic syndromes in Spain was €30,775 and €10,132 respectively. That’s about $31,895 and $10,500 at current exchange rates as of November 2022.53 A similar 2019 study in Sweden determined that total treatment cost, from a patient’s stem cell transplant until death, exceeded $160,000.54 A 2013 study in the Netherlands found that the average cost for an initial AML treatment alone was €117,495 in 2008 and 2009, or about $121,771 at current exchange rates as of November 2022.55.

Source: https://www.pfizer.com/disease-and-conditions/leukemia#:~:text=Leukemia%20is%20caused%20by%20genetic%20changes%20in%20blood%20cells%20produced,the%20risk%20for%20acute%20leukemia.

Life, after going through all the treatment for leukemia, he later died, may sickness and suffering never end our lives, it is such a pathetic situation

You can imagine if this kind of sickness gets a poor man I bet he won't last this long except God interverns.
May his soul RIP

Leukemia, a very deadly disease !!

This life is somehow not balanced. Those that the angel of death is supposed to take, it won't take them. I swear, majority of us Nigerians would have celebrated, thrown a party, if it happened to Buhari while in office then ..

Baba fell terribly sick, make he comot, he nor gree !!

As for the dead governor, if he did the right thing while in office, may the good Lord have mercy upon his soul, if not so, he should rot in hell fire, where there's gnashing of teeth, because these politicians are too wicked ! God forbid!!

Again, others politicians will never see and learn that everything is truly vanity with all the dollars, nairas, etc. Stockpiled in foreign accounts and in their mansions ...

Curse of Ondo State people is among what killed him, he sells the forests they used to farms.

May his soul rest in peace

What do we care While he was sick,nobody came out to tell us what kind of sickness he was down with.why now??

Years from now, many diseases that has ravished our population will become extinct, sadly new ones would emerge to take their place 💔

So sad

His or her family will just conclude in their mind na " spiritual arrow "

hopeforcharles:
You can imagine if this kind of sickness gets a poor man I bet he won't last this long except God interverns.
May his soul RIP

K

Leukamia. The same sickness that infected former super eagles goal keeper. I forgot his name. Since then wev not had a decent keeper.

Cancers are destructive. Leukemia is especially so.
Avoid its triggers and risks as outlined.

Calitoscassius:
No one can avoid cancer, cancer is not infectious, cancer cannot be avoided, so many people who died of cancer lived healthy lives, ate the right food, never smoked, did exercise avoided alcohol, yet they still had cancer and died.

Seek the right knowledge, don't use sentiment. Cancers are highly hereditary, yet very avoidable with the most right steps; early detection, early therapy, ... Many procedures like -ectomy, -paxy, -ostomy, -oscopy..., as suit, help sort it when done early.

Edusouls:
the disease is an enigma is defies human understanding and science

Lol, says who, there's a vast understanding of cancer oga... you think people are sleeping? It's just its therapies usually have strong complications. It's treatment creating other issues.

Hmmm. Nawao . Like play, like play, this man is gone. Rip

Rest on Governor Rotimi Akeredolu

May the bereaved be comforted

It is appointed unto man once to die, after this Judgement!!

No one is leaving this planet awake if Jesus tarries.

We will all sleep. Some to eternal damnation, others to eternal glory. Destinations determined by how we live our lives here. God has prescribed the way to eternal glory ; Jesus Christ The Lord.
Accept and confess HIM today

Hmm

Are U sure this heard prostrate cancer?

RIP Aketi. I will always remember you for AMOTEKUN

Karl Ikeme comes to mind

Big man disease no concern me

.

Sun re o Arakunrin

Life is transient..


I don't know how those who buried their passion on materialism feel after death..

Vanity upon vamity

We move..

Imagine a world without Sicknesses & Diseases.

If not for that foolish Eve wey go chop apple. All of us for dey enjoy paradise now.

Ayya, rest in peace akeredolu, i don't know how politicians feel anytime one of them is gone

nlfpmod:
Source: https://saharareporters.com/2023/12/27/breaking-ondo-governor-akeredolu-dies-after-prolonged-battle-leukemia?fbclid=IwAR0n2-XKc_3F_tJCP5jRHt4ZGkpgKMAfmHwOUM7qg2AUiSdCV6dToUOF-NE




Source: https://www.pfizer.com/disease-and-conditions/leukemia#:~:text=Leukemia%20is%20caused%20by%20genetic%20changes%20in%20blood%20cells%20produced,the%20risk%20for%20acute%20leukemia.

Na prostrate kill am no be leukemia.

According to the official statement released by Ondo State Government, Akeredolu died of Prostate Cancer.

Okay.