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Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials - Health - Nairaland

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Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by solagist(op): 3:35am On Mar 31, 2020
The Director General of the National Agency for Food and Drug Administration and Control, Prof Mojisola Adeyeye, on Monday, ordered manufacturing of chloroquine for emergency stock for possible clinical trial treatment of coronavirus.

The NAFDAC boss in a statement, said the anti-malaria drug was reported to function as anti-viral at both the entry and post-entry stages of 2019-nCoV infection. She added that chloroquine had also been reported as potential broad spectrum anti-viral drug.

She noted that Lagos would begin clinical trial of the drug to evaluate its effectiveness , while calling on the public to desist from its use without the guidance of a medical doctor or clinician for cases of clinical trial treatment of COVID-19.

She said, “Chloroquine, an old anti-malarial, is being re-purposed for the clinical trial treatment of coronavirus 2019-nCoV. The drug was first tested in vitro (in the lab) using standard assays to measure the effects on the cytotoxicity, virus yield and infection rates of 2019-nCoV.

The drug was reported to function as antiviral at both the entry and post-entry stages of 2019-nCoV infection . Chloroquine has also recently been reported as potential broad spectrum antiviral drug. In a very recent publication, chloroquine was reported in a press briefing by the State Council of China, indicating that chloroquine phosphate had demonstrated marked efficacy and acceptable safety in treating COVID-19 associated pneumonia in a multi-center clinical trial conducted in China.

“The study involved 10 hospitals in Wuhan, Jingzhou, Guangzhou, Beijing, Shanghai, Chongqing and Ningbo, and 100 patients. The investigators reported that chloroquine phosphate is superior to the control in inhibiting the pneumonia associated with COVID-19, and shortening the course of the disease.”

The DG of NAFDAC noted that the drug was discontinued in Nigeria many years ago for use as anti-malarial because of the resistance that the parasite developed against it.

She said, “Therefore, sourcing the raw material – active pharmaceutical ingredient- chloroquine phosphate could be difficult.

“About four weeks ago, I approached a local manufacturing company (May and Baker), a member of Pharmaceutical Manufacturing Group of Manufacturing Association of Nigeria, whose flagship product in the past was chloroquine, to make a batch of the drug for emergency stock. The company had NAFDAC approval for the production of the drug as anti-malarial many years ago before the discontinuation.”

According to Adeyeye, despite initial difficulty expressed by the managing director of the company, the hurdle was later removed, leading to the production of the drug with more to be manufactured.

She added, “He called shortly after that he was able to get the API and was asked to manufacture a batch for emergency stock just in case more people become exposed and infected with the virus. The batch has been manufactured and the company plans to make more batches if needed.
https://www.google.com/amp/s/punchng.com/nafdac-orders-emergency-chloroquine-production/%3famp=1

Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by nobone(f): 3:41am On Mar 31, 2020
The same chloroquine?
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by edo3(m):
By 10am ds morning,, God would reveal himself to mankind.. Today corona will be thing of d past says the Lord,, God of all flesh...

Don't bother to quote me, am just his messenger... But believe!!!

Am glad a lot of people are awake,, corona is a loser,, thou says the LORD of host.. He will not fold his hands and allows what he wonderfully made to be destroyed by men of the world..

Lets all join our heart in prayers..
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by ademasta(m): 4:24am On Mar 31, 2020
Hmmmmmmm!
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by opalu: 4:25am On Mar 31, 2020
Till now?
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Eriggs: 4:25am On Mar 31, 2020
The Director General of the National Agency for Food and Drug Administration and Control, Prof Mojisola Adeyeye, on Monday, ordered manufacturing of chloroquine for emergency stock for possible clinical trial treatment of coronavirus.
The end of Covid-19 is upon us. Halleluyah
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Eriggs: 4:25am On Mar 31, 2020
nobone:
The same chloroquine?
Yes, Same one
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by valarmorghulis: 4:26am On Mar 31, 2020
Overdose loading
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Eriggs: 4:26am On Mar 31, 2020
edo3:
By 10am ds morning,, God would reveal himself to mankind.. Today corona will be thing of d past says the Lord,, God of all flesh...

Don't bother to quote me, am just his messenger... But believe!!!
I say Amen
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by dollarsplenty(m): 4:26am On Mar 31, 2020
The good news is that we still have chloroquine around even with the said discontinuation of its production. Let Nafdac give more companies the right to produce the drug.
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Nobody: 4:26am On Mar 31, 2020
Follow follow country..
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Nobody:
.
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Inkling(f):
Good news

I hope it has been refined

Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by iammo(m): 4:28am On Mar 31, 2020
cool
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by olaskul(m): 4:28am On Mar 31, 2020
I believe Nigeria will disappoint the whole world.
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by yusufobinna1(m): 4:29am On Mar 31, 2020
Thank God, we will pass over this
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Ayantoyeopeyem(f): 4:30am On Mar 31, 2020
edo3:
By 10am ds morning,, God would reveal himself to mankind.. Today corona will be thing of d past says the Lord,, God of all flesh...

Don't bother to quote me, am just his messenger... But believe!!!
Amen. I believe
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by splendid2: 4:31am On Mar 31, 2020
Thank God o.

But just imagine 1 small sickness that ordinary chloroquine can cure shut down the whole world. Knowledge is power indeed.

That's how it will be the day they will discover a cure to HIV
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by handsomeyinka(m):
The stone which the builders refused has become the head stone of the corner.

Every condemnations from our enemies will work in our favour in Jesus name..AMEN.

Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by chloedogie(m): 4:31am On Mar 31, 2020
What I have noticed about this coronavirus is that if you have 5 symptoms and have different drugs that can combat those 5 different illnesses then you should be fine. This virus will not come near us and will end soon by God's grace. Also adhere to all precautionary measures rolled out by NCDC and WHO. Stay safe my people.
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by GistFullGround:
The rejected medicine is now the cornerstone...

Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Bethel95(m): 4:33am On Mar 31, 2020
Nice update
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by SoNature(m): 4:33am On Mar 31, 2020
Naija
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Sweetchilli(f): 4:33am On Mar 31, 2020
Why did it take them so long to order clinical trials undecided
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Morganaliticus: 4:34am On Mar 31, 2020
nwanna89:
Same chloroquine that was banned by same nafdac.

In as much as this development is welcome, has the root cause of its initial ban been addressed?
It was banned because the malaria parasite had grown resistant to it, continuing it's production wasn't advised.
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Lizzydonnah(f): 4:35am On Mar 31, 2020
Thank God o. I'm tired of staying at home
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Kfed4ril(m): 4:35am On Mar 31, 2020
Hmmm
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by ta4ba3(m): 4:35am On Mar 31, 2020
We shall survive dis
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by Nobody: 4:37am On Mar 31, 2020
Soon any drug wey get quine for him name wont be available.
Re: Coronavirus: NAFDAC Orders Chloroquine Manufacture For Possible Clinical Trials by GoshenNLA(m): 4:38am On Mar 31, 2020
That chloroquine dey itch body die, i so dislike it
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