Like the vast majority of molecules such as benzodiazepine, zolpidem has no affinity α and α receptors that contain the subunit's. zolpidem positively regulates the GABAA receptors, presumably by increasing convergence of GABAA receptor complex it seems to GABA without affecting sensitivity or the peak current. such as zaleplon (Sonata), zolpidem may increase slow-wave sleep, but do not cause any impact on stage sleep.

Meta-analysis of has shown, randomized trials, controlled Marz Sprays clinical that compared benzodiazepines against nonbenzodiazepines such as zolpidem some differences fixed between zolpidem and benzodiazepines in terms of latency sleep onset, total sleep time, and the number of waking and sleep quality, and adverse events, tolerance, rebound insomnia, and vigilance during the day.


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