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Good News For Diabetics: Pharmacists Converts Insulin Into Tablet Form by adeoladrg(m): 1:26pm On Dec 19, 2013 |
I wil always advocate anywhere,that with training that a pharmacists receives on drugs,as far as drugs are concerned,nothing is impossible, who would ever believe that insulin might some day come in tablets..well don't open your mouth it is happening already...... http://mypharmacymydream./2013/12/19/there-could-more-hope-for-daibetics-with-packaging-insulin-into-a-pill-friendly-form-for-diabetes-treatment/ There Could More Hope For Diabetics With Packaging Insulin Into A Pill-friendly Form For Diabetes Treatment Abstract: Since insulin’s crucial discovery nearly a century ago, countless diabetes patients have had to inject themselves with the life-saving medicine. Now scientists are reporting a new development toward a long-sought insulin pill that could save millions the pain of daily shots. Published in the ACS journal Biomacromolecules, the advance could someday not only eliminate the “ouch” factor, but also get needle-wary — and weary — patients to take their medicine when they should. Packaging insulin into a pill-friendly form for dia insulin therapy. For years, researchers have sought a way to transform delivery of this therapy from a shot to a pill, but it has been a challenge. The body’s digestive enzymes that are so good at breaking down food also break down insulin before it can get to work. In addition, insulin doesn’t get easily absorbed through the gut into the bloodstream. To overcome these hurdles, Jain’s team combined two approaches to shield insulin from the digestive enzymes and then get it into the blood. They packaged insulin in tiny sacs made of lipids, or fats, called liposomes, which are already used in some treatments. Then, they wrapped the liposomes in layers of protective molecules called polyelectrolytes. To help these “layersomes” get absorbed into the bloodstream, they attached folic acid, a kind of vitamin B that has been shown to help transport liposomes across the intestinal wall into the blood. In rats, the delivery system lowered blood glucose levels almost as much as injected insulin, though the effects of the layersomes lasted longer than that of injected insulin. The authors acknowledge funding from the Department of Science & Technology (India) and the Council of Scientific and Industrial Research, New Delhi. 3 Likes |
Re: Good News For Diabetics: Pharmacists Converts Insulin Into Tablet Form by Samgreguc(m): 5:15pm On Dec 19, 2013 |
Wow! I love this. . . . . Cool to hearing |
Re: Good News For Diabetics: Pharmacists Converts Insulin Into Tablet Form by adeoladrg(m): 11:05pm On Dec 21, 2013 |
I used to hear about enteric coating. Just wondering why it didn't work for insulin. Diabetics out there need to see this, tho tmyt not be commercially available yet, its surely a relief. 1 Like |
Re: Good News For Diabetics: Pharmacists Converts Insulin Into Tablet Form by Samgreguc(m): 8:10am On Dec 22, 2013 |
By the time it(drugs) gets to Nigeria, d price myt increase. |
Re: Good News For Diabetics: Pharmacists Converts Insulin Into Tablet Form by lyfe(m): 5:28pm On Dec 29, 2013 |
Well nothing is impossible as far as science and technology is concerned, but insulin is administered subcutaneously and absorbed in the body through that route only because of its fragile nature. Even if it enteric coated the potency of the drug will be lost before it gets to the site where it is needed. |
Re: Good News For Diabetics: Pharmacists Converts Insulin Into Tablet Form by adeoladrg(m): 8:19pm On Dec 29, 2013 |
What is the plan of coating a drug? Is it not to shield it from Hcl in the stomach? Why is insulin different? #okbye |
Re: Good News For Diabetics: Pharmacists Converts Insulin Into Tablet Form by lyfe(m): 12:14am On Dec 30, 2013 |
Not only for stomach acid. But also for conveniency and to sustainably release the active ingredient in drug over time which will not necessitate the need to take a medication over an over again to complete a dosage regime. I am just passing this as another story with no concrete evidence just as we hear different news about cure for HIV everyday with nothing in market. |
Re: Good News For Diabetics: Pharmacists Converts Insulin Into Tablet Form by billyG(m): 4:14pm On Jan 03, 2014 |
Why didnt they develop an insulin skin patch instead. |
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