The world's first malaria vaccine has cleared one of the final hurdles prior to being approved for use in Africa.
The European Medicines Agency gave a positive scientific opinion after assessing its safety and effectiveness.
It represents a 'green light' for the Mosquirix jab, developed by GlaxoSmithKline.
The World Health Organization will consider later this year whether to recommend it for children, among whom trials have yielded mixed results.
Malaria kills around 584,000 people a year worldwide, most of them children under five in sub-Saharan Africa.
'Dream come true'
Mosquirix, otherwise known as the RTS,S vaccine, is the first against a parasitic infection in humans.
Dr Ripley Ballou, head of research at GSK vaccines, said: "This is a hugely significant moment. I've been working on this vaccine for 30 years and this is a dream come true."
The company has not revealed the price of the vaccine, but has pledged not to make a profit from it.
World map of populations at risk from malaria
It has been designed specifically to combat malaria infection in children in Africa and will not be licensed for travellers.
Earlier this year, final results of a clinical trial in seven African countries yielded mixed results.
The best protection was among children aged five to 17 months who received three doses of the vaccine a month apart, plus a booster dose at 20 months.
In this group, cases of severe malaria were cut by a third over four years.
But the effectiveness of the vaccine waned over time, making the booster shot essential.
Without a booster the vaccine did not cut the rate of severe malaria over the trial period.
And disappointingly, the jab did not prove very effective in protecting young babies from severe malaria.
This presents a dilemma for the WHO, which will decide in October whether the vaccine should be deployed, because it is not nearly as effective as scientists would have hoped.
The malaria parasite Plasmodium falciparum is carried by the female anopheles mosquito
http://www.bbc.com/news/health-33641939


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