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5 Worst Mutations That Ever occurred in Human History by Thepasserby(m): 8:45am On Apr 22, 2017
1. Proteus Syndrome

In conjunction with neurofibromatosis type I, this is the disease that likely afflicted Joseph Merrick, the so-called Elephant Man. It’s a condition in which bones, skin, and other tissues are overgrown.

Individuals typically have organs and tissues that grow out of proportion with the rest of their body, and because the overgrowth varies and exhibits no apparent order, it can result in strange and imbalanced features.

Signs of the disorder don’t usually appear until about 6 to 18 months after birth. The severity of proteus syndrome varies from individual to individual, and it occurs in less than one in one million people. And in fact, only a few hundred documented cases have ever been reported.

Copied from www.palmchatnow.com

Re: 5 Worst Mutations That Ever occurred in Human History by Thepasserby(m): 8:47am On Apr 22, 2017
2. Ectrodactyly

Formerly known as “lobster claw hand, ”individuals with this disorder have a cleft where the middle finger or toe should be. These split-hand/split-foot malformations are rare limb deformities which can manifest in any number of ways, including cases including only the thumb and one finger (typically the little finger or little finger). It’s also associated with hearing loss.

Re: 5 Worst Mutations That Ever occurred in Human History by dingbang(m): 8:50am On Apr 22, 2017
grin
Re: 5 Worst Mutations That Ever occurred in Human History by Thepasserby(m): 8:52am On Apr 22, 2017
3. Epidermodysplasia Verruciformis

Epidermodysplasia verruciformis is an extremely rare disorder that makes people prone to widespread human papillomavirus (HPV) infection.

This infection causes scaly macules and papules (cutaneous squamous cell carcinomas) to grow on the hands, feet, and even face. These skin “eruptions” appear as wart-like lesions — and even wood-like and horn-like growths — with reddish-brown pigmented plaques. Typically, the skin tumors start to emerge in people between the age of 20 and 40, and the growths tend to appear on areas exposed to the sun.

Also called Lewandowsky-Lutz dysplasia, there is no known cure, though treatments to scale back the growths are possible.

Re: 5 Worst Mutations That Ever occurred in Human History by Thepasserby(m): 8:55am On Apr 22, 2017
4. Hypertrichosis

People with hypertrichosis have excessive hair on the shoulders, face, and ears. Studies have implicated it to a rearrangement of chromosome 8. It happens due to a disruption of the “crosstalk” between the epidermis and the dermis as hair follicles form in the 3-month fetus at the eyebrows and down to the toes.

Re: 5 Worst Mutations That Ever occurred in Human History by Thepasserby(m): 8:56am On Apr 22, 2017
5. Progeria

This genetic disorder is as rare as it is severe. The classic form of the disease, called Hutchinson-Gilford Progeria, causes accelerated aging.


Most children who have progeria essentially die of age-related diseases around the age of 13, but some can live into their 20s. Death is typically caused by a heart attack or stroke. It affects as few as one per eight million live births.

Re: 5 Worst Mutations That Ever occurred in Human History by number5(m): 9:00am On Apr 22, 2017
Thepasserby:
3. Epidermodysplasia Verruciformis

Epidermodysplasia verruciformis is an extremely rare disorder that makes people prone to widespread human papillomavirus (HPV) infection.

This infection causes scaly macules and papules (cutaneous squamous cell carcinomas) to grow on the hands, feet, and even face. These skin “eruptions” appear as wart-like lesions — and even wood-like and horn-like growths — with reddish-brown pigmented plaques. Typically, the skin tumors start to emerge in people between the age of 20 and 40, and the growths tend to appear on areas exposed to the sun.

Also called Lewandowsky-Lutz dysplasia, there is no known cure, though treatments to scale back the growths are possible.


embarassed

3 Likes

Re: 5 Worst Mutations That Ever occurred in Human History by godwinstringed1(m): 9:00am On Apr 22, 2017
Eleyi gidi Gan oooo
Re: 5 Worst Mutations That Ever occurred in Human History by Nobody: 9:06am On Apr 22, 2017
that No. 3 tho..

sure say nor be goat and human produce them? grin grin
Re: 5 Worst Mutations That Ever occurred in Human History by elkraune(m): 1:01pm On Apr 22, 2017
so should we fry beans?
Re: 5 Worst Mutations That Ever occurred in Human History by devilmaycry: 1:05pm On Apr 22, 2017
Thepasserby:
5. Progeria

This genetic disorder is as rare as it is severe. The classic form of the disease, called Hutchinson-Gilford Progeria, causes accelerated aging.


Most children who have progeria essentially die of age-related diseases around the age of 13, but some can live into their 20s. Death is typically caused by a heart attack or stroke. It affects as few as one per eight million live births.
werin we go call this one now.... boyman grin
Re: 5 Worst Mutations That Ever occurred in Human History by ramdris(m): 1:45pm On Apr 22, 2017
OMG! Dear Op, the word "graphic" boldly type in red should be use for thread like dis...

WTF

4 Likes

Re: 5 Worst Mutations That Ever occurred in Human History by KennedyOkpara(m): 1:50pm On Apr 22, 2017

Re: 5 Worst Mutations That Ever occurred in Human History by Zaitoon: 2:29pm On Apr 22, 2017
Thepasserby:
5. Progeria

This genetic disorder is as rare as it is severe. The classic form of the disease, called Hutchinson-Gilford Progeria, causes accelerated aging.


Most children who have progeria essentially die of age-related diseases around the age of 13, but some can live into their 20s. Death is typically caused by a heart attack or stroke. It affects as few as one per eight million live births.
This reminds me of one Indian movie I watched "paa"

3 Likes

Re: 5 Worst Mutations That Ever occurred in Human History by hardbody: 2:36pm On Apr 22, 2017
We thank God ooo. Make our eye no see wetin our mouth no fit pronounce. Eleyi gidi gaan

2 Likes

Re: 5 Worst Mutations That Ever occurred in Human History by nNEOo(m): 2:45pm On Apr 22, 2017
Waw how best can you describe mutation if not in it beautiful and diverse form...."the beauty and diversity of life forms"

that the title of the book when I finally publish it pls look it up cos it quite interesting.
Waw cool
Re: 5 Worst Mutations That Ever occurred in Human History by sbashir10(m): 3:40pm On Apr 22, 2017
mehn, dis is something else. if this should happen in any part of Nigeria, they'll say it is witch craft....

1 Like

Re: 5 Worst Mutations That Ever occurred in Human History by abumeinben(m): 3:46pm On Apr 22, 2017
Expected to find so Nazi things there.

1 Like

Re: 5 Worst Mutations That Ever occurred in Human History by Martinez19(m): 4:18pm On Apr 22, 2017
Thepasserby:
2. Ectrodactyly

Formerly known as “lobster claw hand, ”individuals with this disorder have a cleft where the middle finger or toe should be. These split-hand/split-foot malformations are rare limb deformities which can manifest in any number of ways, including cases including only the thumb and one finger (typically the little finger or little finger). It’s also associated with hearing loss.
Mikhail Tal comes to mind
Re: 5 Worst Mutations That Ever occurred in Human History by gegee(m): 4:46pm On Apr 22, 2017
Wawu

Re: 5 Worst Mutations That Ever occurred in Human History by SolexxBarry(m): 5:12pm On Apr 22, 2017
This is very scary,dat number 3 is suicidal

1 Like

Re: 5 Worst Mutations That Ever occurred in Human History by ShafebProperty(m): 6:08pm On Apr 22, 2017
Zaitoon:
This reminds me of one Indian movie I watched "paa"

one of the best bollywood movies i've ever seen PAA

2 Likes

Re: 5 Worst Mutations That Ever occurred in Human History by irynterri(f): 6:11pm On Apr 22, 2017
Chuvin22:
that No. 3 tho..
sure say nor be goat and human produce them? grin grin
you find this funny??it's not cool to make fun of a persons disability.

6 Likes

Re: 5 Worst Mutations That Ever occurred in Human History by Nobody: 6:18pm On Apr 22, 2017
irynterri:

you find this funny??it's not cool to make fun of a persons disability.

Not trying to make fun.. Just curious how this happened?

1 Like

Re: 5 Worst Mutations That Ever occurred in Human History by Tazdroid(m): 6:18pm On Apr 22, 2017
irynterri:

you find this funny??it's not cool to make fun of a persons disability.

His brain is composed of baby poop and adulterated kerosene

3 Likes

Re: 5 Worst Mutations That Ever occurred in Human History by sureteeboy(m): 6:40pm On Apr 22, 2017
Zaitoon:
This reminds me of one Indian movie I watched "paa"
The guy backed in That picture sure looks like the one the Op illustrated the disease with.
Re: 5 Worst Mutations That Ever occurred in Human History by Zaitoon: 6:50pm On Apr 22, 2017
ShafebProperty:


one of the best bollywood movies i've ever seen PAA
yeah one of the few Bollywood movie that made me cry cry

btw, do you know it was Amitabh Bachchan that was transform into 13-year old child Auro, suffering from a rare disorder called progeria in the movie

2 Likes

Re: 5 Worst Mutations That Ever occurred in Human History by Godian45(m): 8:50pm On Apr 22, 2017
Thank God for medcine,if not this people are to be called agent of darkness.9ja no dey carry last,once u have any of d above genetic abnomalities they will run from u,make i no lie me too go run small o. proudly a pharm student did little genetic pathology grin grin grin grin

1 Like

Re: 5 Worst Mutations That Ever occurred in Human History by Nobody: 9:40pm On Apr 22, 2017
cry
Re: 5 Worst Mutations That Ever occurred in Human History by Qaisar1: 10:53pm On Apr 22, 2017
Meanwhile, some people are complaining about their skin colour, body size. Appreciate God for your looks!
Re: 5 Worst Mutations That Ever occurred in Human History by Nobody: 11:31pm On Apr 22, 2017
elkraune:
so should we fry beans?
You Suck!!!

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