Treatment of hepatitis C has been reported to be effective in trials conducted in three African countries, according to a report presented by Dr Karine Lacombe recently. This is based on the preliminary results of an ongoing clinical trial evaluating the safety and effectiveness of new antivirals in persons with Hepatitis C in three African countries: Cameroon, Senegal and Cote d’lvoire . The researchers included 12 persons living with Hepatitis C that had never received any form of treatment.

The following medicines were found to be effective in different combinations:

Sofobuvir
Ribavirin
Ledipasvir
The result was presented at the 9th IAS Conference on HIV Science in Paris, on August, 1 2017.

According to the main author of the study, Dr Lacombe, an associate professor at Saint-Antrine Hospital, France, “The treatment of chronic Hepatitis C by Direct-Acting Antivirals (DAAs) is possible in the African context with good adherence, good safety and a laboratory follow-up that poses no particular difficulty. Prof. Alain Attia of CHU Yopougon, Abidjan in Cote d’lvoire and myself ran the trial. It included 120 patients with chronic Hepatitis C, who had never been treated for the infection. Each of the three most frequent HCV genotypes (1, 2 and 4) were represented by 40 patients. Patients with genotype 2 HCV were treated with the DAA sofobuvir plus ribavirin. Those with genotype 1 or 4 HCV were given a combination of 2 DAAs (sofobuvir and ledipasvir) in the form of a single tablet for 12 weeks.”


Source:http://www.healthx24.com/hepatitis-treatment-africa/

Hepatitis C is a liver disease caused by the hepatitis C virus: the virus can cause both acute and chronic liver disease, which may be mild or severe. Globally, an estimated 71 million people have chronic hepatitis C and close to 400,000 die yearly. It is important to note that Hepatitis C does not always require treatment because the body’s defenses may fight it on its own. However, some people with chronic infection need these medicines to clear the infection and prevent chronic liver problems. Although, treatment is available, most people in resource constrained settings do not have access to treatment. Therefore, finding cheap, affordable treatments in Africa and other low income settings is laudable. Happily, the introduction of generic forms of these medicines have brought down the prices remarkably.

www.healthx24.com/hepatitis-treatment-africa/

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