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Possibility Of AA+AS Genotype Parent Give Birth To SS - Exper Opinion Needed - Health - Nairaland

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Possibility Of AA+AS Genotype Parent Give Birth To SS - Exper Opinion Needed by Bigajeff(op): 9:08pm On Dec 06, 2017
This is the genotype possibility I'm sure of but I stand to be corrected if I'm wrong.

AA+AA= AA,AA(Good)AA+AS= AA,AS(Good)AA+SS= AS,AS(Good)AA+AC= AA,AC(Good)AS+AS= AA,AS,SS (Bad)AS+SS= AS,SS (Bad)SS+SS= SS,SS (Bad)AS+AC= Need adviceAC+SC= Need adviceAC+SS= Need advice.

But can AA + AS = SS I'm still arguing this is not possible. I need expert advice for this possibility.

mod, lalasticlala please let this hit the frontpage
Re: Possibility Of AA+AS Genotype Parent Give Birth To SS - Exper Opinion Needed by python1: 9:19pm On Dec 06, 2017
That is a future impossible tense. grin grin grin
Whichever permutation you use, you must end up with either AA or AS, and the last time I checked, AS can never be SS.
Re: Possibility Of AA+AS Genotype Parent Give Birth To SS - Exper Opinion Needed by Nobody: 9:24pm On Dec 06, 2017
It is very possible, especially if the woman plays away match. grin
Re: Possibility Of AA+AS Genotype Parent Give Birth To SS - Exper Opinion Needed by SmallmebigGod: 11:45pm On Dec 06, 2017
Bigajeff:
This is the genotype possibility I'm sure of but I stand to be corrected if I'm wrong.

AA+AA= AA,AA(Good)AA+AS= AA,AS(Good)AA+SS= AS,AS(Good)AA+AC= AA,AC(Good)AS+AS= AA,AS,SS (Bad)AS+SS= AS,SS (Bad)SS+SS= SS,SS (Bad)AS+AC= Need adviceAC+SC= Need adviceAC+SS= Need advice.

But can AA + AS = SS I'm still arguing this is not possible. I need expert advice for this possibility.

mod, lalasticlala please let this hit the frontpage
This has been trashed here with threads and counter threads just search.
The only possibility is if the AA is not actually AA genotype I.e it was determined by HB electrophoresis alone. This person might actually be genotype A with a thalassemic trait but misdiagnosed as AA.
A co inheritance of S gene and the thalassemic that may occur known SB thal can also present like SS and has also been misdiagnosed as SSS
Re: Possibility Of AA+AS Genotype Parent Give Birth To SS - Exper Opinion Needed by Qmedspharma(m): 6:45am On Dec 07, 2017
Bigajeff:
This is the genotype possibility I'm sure of but I stand to be corrected if I'm wrong.

AA+AA= AA,AA(Good)AA+AS= AA,AS(Good)AA+SS= AS,AS(Good)AA+AC= AA,AC(Good)AS+AS= AA,AS,SS (Bad)AS+SS= AS,SS (Bad)SS+SS= SS,SS (Bad)AS+AC= Need adviceAC+SC= Need adviceAC+SS= Need advice.

But can AA + AS = SS I'm still arguing this is not possible. I need expert advice for this possibility.

mod, lalasticlala please let this hit the frontpage
It is absolutely impossible. They can only have AS but not SS.
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