COVID-19: Experimental drug remdesivir failed in human trial —Punch Newspaper
Published April 23, 2020


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The experimental antiviral drug remdesivir has failed in its first randomized clinical trial to treat the COVID-19 illness, reports said Thursday, quoting draft documents that were accidentally published by the World Health Organization.


Gilead Sciences, the company behind the medicine, disputed how the now-deleted post had characterized the findings, saying the data showed a “potential benefit.”

The Financial Times reported that researchers in China carried out a study on 237 patients, giving the drug to 158 and comparing their progress with a control group of 79.

A summary of the experiment said remdesivir was “not associated with a difference in time to clinical improvement” compared to the control, according to health news site Stat, which posted a screenshot.


After a month, 13.9 percent of the patients on remdesivir had died compared to 12.8 per cent of those in the control group.


A spokesman for Gilead told AFP: “We believe the post included inappropriate characterizations of the study,” saying it was terminated early due to low enrollment and was therefore not statistically meaningful.

“As such, the study results are inconclusive, though trends in the data suggest a potential benefit for remdesivir, particularly among patients treated early in disease,” he said.

The study does not represent the final word on the matter and there are several large-scale trials in advanced stages that should soon provide a clearer picture.


Remdesivir, which is administered intravenously, was among the first drugs mooted as a treatment for the novel coronavirus and as such has great hopes riding on it.

Last week, Stat reported it had shown significant efficacy at a Chicago hospital where patients who are part of one of the major trials are being treated.

The US National Institutes for Health also reported it had proven effective in a small experiment on monkeys.


Remdesivir belongs to a class of drugs that act on the virus directly — as opposed to controlling the abnormal and often lethal autoimmune response it causes.

It mimics one of the four building blocks of RNA and DNA and gets absorbed into the virus’s genome, which in turn stops the pathogen from replicating.

AFP.
https://www.google.com/search?q=punch+news+COVID+drug+failed+test&oq=Punch+&aqs=chrome.0.69i59l3j69i60j69i57j69i60.6060j0j4&client=ms-android-transsion-tecno-rev1&sourceid=chrome-mobile&ie=UTF-8

Ok

This Coronavirus self is stubborn. Haba na only you waka come

We are in for the long haul

Brace up for another month of lockdown

Nawaooo just when we taught it's over it keeps coming back.......I miss my boyfriend like kilode

Millenniumlady:
Nawaooo just when we taught it's over it keeps coming back.......I miss my boyfriend like kilode

Your boyfriend is lucky

Hope he mizzez you too?

ogawriter:


Your boyfriend is lucky

Hope he mizzez you too?

Please stop quoting me he's on this forum

Millenniumlady:
Please stop quoting me he's on this forum

This is a public forum and is there anything wrong or offensive in what I said?

ogawriter:


This is a public forum and is there anything wrong or offensive in what I said?

I won't repeat myself

They should keep trying. Our pastors are secretly hoping scientists will come up with a cure soon

Millenniumlady:
I won't repeat myself

Like I care

ogawriter:


Like I care

I'll make you to deactivated your acct if you're not careful

Millenniumlady:
I'll make you to deactivated your acct if you're not careful

Lol

ogawriter:


Lol

Nigga get the fu*k out of my mention

Really getting confused over this virus

I was counting on this drug to do the magic since it was first touted last week.

Note: The topic is misleading; its a drug, not a vaccine pls.

Ladies and gentlemen, may God help us all.

Amen.

Notyamate:
This Coronavirus self is stubborn. Haba na only you waka come

it's not a vaccine at all, that op is mad...they are only trying to use EBOLA drugs to cure covid-19 which is redemvisir(antiviral drug)

Ewo.

No comment

Valro:
They should keep trying. Our pastors are secretly hoping scientists will come up with a cure soon

The people developing the cure, are they atheist?

You guys talk fullishly sometimes.

The people developing the cure still have pastors, imams and faith leaders they look up to for spiritual guidance.

Your headline says "Trial Vaccine" your story says "Trial Drugs" are you aware they are different items? We keep getting things mixed up just for traffic.

ChristianNorth:

The people developing the cure, are they atheist?

You guys talk fullishly sometimes.

The people developing the cure still have pastors, imams and faith leaders they look up to for spiritual guidance.

Oga if you cannot write down your comments here precisely without quoting me, then take the next flight to hell or better still trek, am entitled to my opinion and you are not to judge if its foolish or not. Science and religion work hand in hand and at the same contradicting each other. So when I say what I say, I know why I said what I said.

Op correct your title. Is it drug or vaccine?.. do the needful please

Valro:

Oga if you cannot write down your comments here precisely without quoting me, then take the next flight to hell or better still trek, am entitled to my opinion and you are not to judge if its foolish or not. Science and religion work hand in hand and at the same contradicting each other. So when I say what I say, I know why I said what I said.

Like I said, you guys talk fullishly sometimes.

Having opinion doesn't mean you have to be insensitive to people's belief or insults people's profession.

Insulting pastors is utter fullishness.

ChristianNorth:

Like I said, you guys talk fullishly sometimes.

Having opinion doesn't mean you have to be insensitive to people's belief or insults people's profession.

Insulting pastors is utter fullishness.

The way you are pained, you must be a Pastor. I wouldn't want to dive into unnecessary banter with you here seeing you are overly sentimental, more like you are a religious fanatic, whether you consider the stated as insult or not, the fact remains that the world (including your stupid religious leaders) is waiting on science to provide solution, Why haven't you gone for 40 days fasting for virus to dissappear?
I understand your frustration due to this lockdown but kindly help yourself with a bottle of sniper, don't quote me again else I ll worsen your day, am jobless today.

This is a treatment drug not a vaccine. Oga
A vaccine is around the corner

Millenniumlady:
Nawaooo just when we taught it's over it keeps coming back.......I miss my boyfriend like kilode

Woman calm down, make you shame small na. Your puzzy no dey fear Coronavirus This one no be HIV oo

Clinical trials will surely continue and from the look of things, and from what I hear from the BBC, a vaccine would be develop within 18 months.

I still wait to hear news from Africa CDC and what we're doing to battle this bug. We shouldn't be like the student that allows the rest of the of the class to solve a difficult assignment just to end up copying

Skmoda:

it's not a vaccine at all, that op is mad...they are only trying to use EBOLA drugs to cure covid-19 which is redemvisir(antiviral drug)

No need. I mistakenly used the word drug in the title, you only needed to draw my attention to it.

ijayopi:
Your headline says "Trial Vaccine" your story says "Trial Drugs" are you aware they are different items? We keep getting things mixed up just for traffic.

Mistake noted

bolseas:
Op correct your title. Is it drug or vaccine?.. do the needful please

Thanks. Already modified

MyFlair:
This is a treatment drug not a vaccine. Oga
A vaccine is around the corner

Sorry. It's been modified. Thanks