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Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' - Health - Nairaland

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Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by wengerjay(m): 8:34pm On May 19, 2020
A Chinese laboratory has been developing a drug it believes has the power to bring the coronavirus pandemic to a halt.

The outbreak first emerged in China late last year before spreading across the world, prompting an international race to find treatments and vaccines.

A drug being tested by scientists at China's prestigious Peking University could not only shorten the recovery time for those infected, but even offer short-term immunity from the virus, researchers say.

Sunney Xie, director of the university's Beijing Advanced Innovation Center for Genomics, told AFP that the drug has been successful at the animal testing stage.

"When we injected neutralising antibodies into infected mice, after five days the viral load was reduced by a factor of 2,500," said Xie.

"That means this potential drug has (a) therapeutic effect."

The drug uses neutralising antibodies—produced by the human immune system to prevent the virus infecting cells—which Xie's team isolated from the blood of 60 recovered patients.

A study on the team's research, published Sunday in the scientific journal Cell, suggests that using the antibodies provides a potential "cure" for the disease and shortens recovery time.
Sunney Xie, director of the Beijing Advanced Innovation Center for Genomics, told AFP that the drug has been successful at the a
Sunney Xie, director of the Beijing Advanced Innovation Center for Genomics, told AFP that the drug has been successful at the animal testing stage

Xie said his team had been working "day and night" searching for the antibody.

"Our expertise is single-cell genomics rather than immunology or virology. When we realised that the single-cell genomic approach can effectively find the neutralising antibody we were thrilled."

He said he hopes that the drug will be ready for use later this year and in time for any potential winter outbreak of the virus, which has infected 4.8 million people around the world and killed more than 315,000.

"Planning for the clinical trial is underway," said Xie, adding it will be carried out in Australia and other countries since cases have dwindled in China, offering fewer human guinea pigs for testing.

"The hope is these neutralising antibodies can become a specialised drug that would stop the pandemic," he said.

China already has five potential coronavirus vaccines at the human trial stage, a health official said last week.

But the World Health Organization has warned that developing a vaccine could take 12 to 18 months.
Sunney Xie said his team had been working "day and night" on the new drug
Sunney Xie said his team had been working "day and night" on the new drug

Scientists have also pointed to the potential benefits of plasma—a blood fluid—from recovered individuals who have developed antibodies to the virus enabling the body's defences to attack it.

More than 700 patients have received plasma therapy in China, a process which authorities said showed "very good therapeutic effects".

"However, it (plasma) is limited in supply," Xie said, noting that the 14 neutralising antibodies used in their drug could be put into mass production quickly.

Prevention and cure

Using antibodies in drug treatments is not a new approach, and it has been successful in treating several other viruses such as HIV, Ebola and Middle East Respiratory Syndrome (MERS).

Xie said his researchers had "an early start" since the outbreak started in China before spreading to other countries.

Ebola drug Remdesivir was considered a hopeful early treatment for COVID-19—clinical trials in the US showed it shortened the recovery time in some patients by a third—but the difference in mortality rate was not significant.
More than 100 vaccines for COVID-19 are in the works globally
More than 100 vaccines for COVID-19 are in the works globally

The new drug could even offer short-term protection against the virus.

The study showed that if the neutralising antibody was injected before the mice were infected with the virus, the mice stayed free of infection and no virus was detected.

This may offer temporary protection for medical workers for a few weeks, which Xie said they are hoping to "extend to a few months".

More than 100 vaccines for COVID-19 are in the works globally, but as the process of vaccine development is more demanding, Xie is hoping that the new drug could be a faster and more efficient way to stop the global march of the coronavirus.

"We would be able to stop the pandemic with an effective drug, even without a vaccine," he said.https://medicalxpress.com/news/2020-05-scientists-china-drug-pandemic-vaccine.html

1 Like

Re: Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by Nobody: 8:36pm On May 19, 2020
Mm this is good news.

anyway let me go and take the special Agbo from madagascar. grin Na that one sure pass.
Re: Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by wengerjay(m): 8:37pm On May 19, 2020
Once the world is healed, we don't care who takes the credits.
Anyway, we have accorded the Chinese the respect as the most powerful in the world if that is her goal.
Please make u free the world.
Re: Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by olamidedivotee(f): 8:38pm On May 19, 2020
hmm
Re: Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by Makavelli25: 8:45pm On May 19, 2020
Earn up to 5k daily Check link in my signature
Re: Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by sweetmelanin(f): 8:49pm On May 19, 2020
Why so much emphasis on 'stopping' this lab-manufactured 'virus'?

Coronavirus is not a death sentence! - majority of those who get it are able to recover without treatment. Afterall, we've been existing with all sorts of viruses in this world for decades and centuries.. our natural immune system is able to defeat all sorts of ailment .. so why the fuss about a virus with such a low death rate, lower than the common Flu!

lipsrsealed

4 Likes

Re: Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by EzzyCarter: 8:54pm On May 19, 2020
Your melanin is obviously not the only thing sweet about you. You've got a sweet brain too cheesy . Check out the way the major media firms like CNN , BBC, Daily Mail and the likes are overblowing things to strike fear into the minds of people... Corona can kill, fine but it obviously shouldn't be the end of the world...
Re: Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by wengerjay(m): 6:01am On May 20, 2020
May God rescue the mankind from this menace called Corona virus that is eating deep into the fabric of human existence.

1 Like

Re: Scientists In China Believe New Drug Can Stop Pandemic 'without Vaccine' by Nobody: 7:45am On May 20, 2020
World keep disturbing their self about a virus that ordinary chloroquine can cure. Substandard virus from the Chinese. Next time develop better virus

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