The United Kingdom is set to be the first country in the world to test a vaccine against coronavirus by infecting healthy volunteers with Sars-Cov-2, the Financial Times reported, citing several people involved in the study.

In so-called “COVID-19 human challenge trials”, which will be funded by the UK government, participants will receive the vaccine and then, approximately a month later, a “challenge” dose of Sars-Cov-2 which normally causes the coronavirus-related disease.

The trials, which are more controversial than traditional studies, are set to “play a vital role in narrowing the large field of promising COVID-19 vaccines”, according to the report, by basically directly assessing their effectiveness.

The project will be reportedly carried out in a security quarantine facility run by hVivo, which is located in Whitechapel, London and is expected to launch in January. The conditions of people involved in the study will be monitored, as nearly 2,000 participants have already signed up for the trials in the UK alone through 1Day Sooner, a US-based project.

According to sources familiar with the matter, the necessary announcement it is expected to be made next week.

The UK Medicines and Healthcare Products Regulatory Agency told the FT that such trials “can be helpful for the development of vaccines and can provide early evidence of clinical efficacy, particularly when there are low rates of infection of the virus in the population".

“The safety of trial participants is our top priority and any proposal from a developer to include a human infection challenge as part of a clinical trial for development of a vaccine would be considered on a benefit-risk basis, with risks monitored for, and minimised in, the proposed trial design,” the agency said in a statement.


According to the FT, previous partakers of hVivo’s influenza challenge studies have received a payment of up to £3,750 ($4,764), but reimbursement for COVID-19 research could be much higher due to the longer period of the participants’ isolation – however, the exact sum remains unknown.

https://sputniknews.com/uk/202009241080556540-uk-to-deliberately-infect-volunteers-with-coronavirus-to-test-anti-covid-vaccine/

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