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Pfizer Is Testing A Cure For COVID-19: PF-07321332 - Health - Nairaland

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Pfizer Is Testing A Cure For COVID-19: PF-07321332 by lalasticlala(m): 1:16pm On Apr 27
Pfizer is testing a pill that, if successful, could become first-ever home cure for COVID-19

Classed as a 'protease inhibitor', it has been formulated to attack the "spine" of the SARS-CoV-2 virus and stop it replicating in our nose, throats and lungs.

At two anonymous Pfizer buildings, one in the U.S. and one in Belgium, a remarkable experiment is under way. Up to 60 volunteers, all clean-living adults aged between 18 and 60, are being given the first pill specifically designed to stop Covid-19.

If the trial is successful, it is just possible a home cure for Covid-19 will become available later this year. U.K. Prime Minister Boris Johnson, who announced the formation of an “Antivirals Taskforce” last week specifically to invest in such products, will no doubt be scanning his text messages for early updates.

The molecule being tested is a bespoke antiviral code-named PF-07321332. Classed as a “protease inhibitor”, it has been formulated to attack the “spine” of the SARS-CoV-2 virus and stop it replicating in our nose, throats and lungs.
It was protease inhibitors that turned the tide on the spread of HIV in the UK and around the world. Now researchers hope they may be on the brink of a similar pandemic-busting breakthrough.

“If they have moved to this stage they will be quietly optimistic,” said Penny Ward, a visiting professor in pharmaceutical medicine at King’s College London and a pioneer in the development of Tamiflu, an antiviral that combats seasonal and pandemic flu. “The question will be about how the drug is tolerated… They will be going like the clappers”.

The antiviral pill was developed from scratch during the current pandemic, Dafydd Owen, director of medicinal chemistry at Pfizer, told a private symposium of the Division of Medicinal Chemistry last month.

The first seven milligrams of the compound – no more than a raindrop — were made in late July 2020. By late October, they’d made 100 grams.

Just two weeks later, they had more than a kilogram in the bag. It took 210 researchers to do it, said Owen.

If they have moved to this stage they will be quietly optimistic

Pfizer is keeping schtum about the detail of the lab tests it has completed but says it has demonstrated “potent in vitro antiviral activity against SARS-CoV-2”, as well as activity against other coronaviruses, raising the prospect of a cure for the common cold as well as future pandemic threats.

“We have designed PF-07321332 as a potential oral therapy that could be prescribed at the first sign of infection, without requiring that patients are hospitalised or in critical care”, said Mikael Dolsten, chief scientific officer and president of worldwide research, development and medical at Pfizer, in a statement released last month.

According to Ward, Pfizer’s scientists will have most likely established the drug’s “potent” action against SARS-CoV-2 by deploying it against infected human tissue cultures, including lung tissue, in a laboratory. “Once you know it works in vitro, it’s all about establishing its tolerance in animals and then humans,” she said.

The Sunday Telegraph has obtained copies of the documents given to participants who are now entering the first human trials.

“To date, the study drug has not been administered to humans,” say the documents which were formally approved on February 8 this year.

“The safety of the study drug has been studied in animals. In these animal studies, no significant risks or safety events of concern were identified, and the study drug did not cause side effects at any of the dose levels that will be used in clinical studies.”

https://montrealgazette.com/news/world/pfizer-is-testing-a-pill-that-if-successful-could-become-first-ever-home-cure-for-covid-19

3 Likes

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Assurance001(f): 1:19pm On Apr 27
FTC

1 Like

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by qualityovenbake(m): 1:19pm On Apr 27
This is good news. Social Distance Au revoir
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by BuyDomain: 1:21pm On Apr 27
Ok
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Officialhorlah(m): 1:22pm On Apr 27
Another one Okay Make we see the outcomegrin

1 Like

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by mike8804: 1:31pm On Apr 27
world of capitalism, whales feeding on sharks and sharks feeding on fishes. Everyone want to cash out

2 Likes

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by dmbb: 1:31pm On Apr 27
Scam

1 Like

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Starrbboyy(m): 1:32pm On Apr 27
Okay

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by zeal22(m): 1:32pm On Apr 27
nice
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Rollingstones86: 1:32pm On Apr 27
But over here our universities and medical students have been on an unending strikes.

5 Likes

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by FarahAideed: 1:33pm On Apr 27
I already have such a pill and I have used it to save many
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by donestk(m): 1:34pm On Apr 27
Those who create the panic will soon start selling the pills

7 Likes

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Deicide: 1:34pm On Apr 27
So which God are they praying to?

2 Likes

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by gaskiyamagana: 1:34pm On Apr 27
I respect this white people.
Many thanks to Almighty God, thanks to the Scientist.

1 Like

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by ogunsbanjul(m): 1:35pm On Apr 27
I pray make these our brothers in that region see the sample before they will be producing fake pills as usual. I didn't mention the tribe o

3 Likes 2 Shares

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by MANNABBQGRILLS: 1:35pm On Apr 27
Let's go there.......

Bye Bye To Coro......

3 Likes 2 Shares

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by labusinessguide: 1:36pm On Apr 27
Awesome

1 Like

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by gaskiyamagana: 1:36pm On Apr 27
FarahAideed:
I already have such a pill and I have used it to save many
Typical PRESIDENCY response to Nigeria froblem.

5 Likes

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by PeaceJoyLove: 1:37pm On Apr 27
Pzifer cashing out neatly. A business plan that had been done like 2 years before Covid-19. First vaccine, next home pill...what next? Special home kit for specific cases. They will never allow HIV cure out. Only to spend money on maintaining it for life. Lol. God dey sha.

6 Likes 1 Share

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by gaskiyamagana: 1:38pm On Apr 27
ogunsbanjul:
I pray make these our brothers in that region see the sample before they will be producing fake pills as usual. I didn't mention the tribe o
They are developing outside, you don't want your bloders to develop Nigeria too?
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Ratedgang: 1:40pm On Apr 27
Covid-19 is an overrated malaria.
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by 1Alex: 1:41pm On Apr 27
ok
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Springboot: 1:42pm On Apr 27
A repacked malaria drug. These people be cashing you with covid

1 Like

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Seniorwriter(m): 1:43pm On Apr 27
All this while? This pharm outfit have been embarking on trial by error for too long! I think they need to get to the root of this Covid19 virus before they'll eventually come out with something worthwhile.

Deep Quote
You can only get a solution to your problem when you discover the root course of the problem.

@Seniorwriter
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Ckonnet: 1:44pm On Apr 27
Anything to cure oyibo people craze is welcomed, china people that ate the bats are chilling o
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by damiloladuke: 1:44pm On Apr 27
AMAZING
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Oskydaniellyyy: 1:47pm On Apr 27
mike8804:
world of capitalism, whales feeding on sharks and sharks feeding on fishes. Everyone want to cash out

lol, what of socialism/communism. which one is always better. A capitalism run country is always better than a socialist state
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Focusmind: 1:47pm On Apr 27
Nawao. Though I respect Pfizer but capitalism is fast taking over this pandemic. I was shocked when I heard the Pfizer CEO said people would have to take additional dose, making it three doses.

Astrazeneca came and said that people would have to be taken the shots yearly to create the required immunity. All na money dem dey find.

This one came out now with tablets.

1 Like

Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by Princeton92(m): 1:48pm On Apr 27
And no cure yet for HIV/AIDS?
Re: Pfizer Is Testing A Cure For COVID-19: PF-07321332 by FiverrTutor(m): 1:48pm On Apr 27
What about a pill to cure HIV Aids

Scammers!!!!

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