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Demand1982's Posts

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ComputersRe: 100 keyboard shortcuts and The A - Z Of All Microsoft Shortcuts by demand1982(op): 11:57pm On Jul 25, 2014
Gosj01: Followin...**spreads pc and laptop**
oya your testimony
AgricultureRe: I Need Maize, Soya Meal And GNC Suppliers by demand1982: 11:49pm On Jul 25, 2014
sp2002: We are a new farm and willing to get in touch with suppliers of maize,soya meal and GNC. We want to buy 3500kg maize, 1tone soya meal and 1 tone GNC. Pls call me on 08137775986
your location
ComputersRe: 100 keyboard shortcuts and The A - Z Of All Microsoft Shortcuts by demand1982(op): 11:42pm On Jul 25, 2014
demand1982: CTRL and A Selects all in the current document.
CTRL and B Bold text.
CTRL and C Copies the item
CTRL and D Fill Down Cell
CTRL and E Centre Alignment.
CTRL and F Displays the Find dialog box, to search the current document.
CTRL and G Displays the Go to dialog box, to go to a specific location in the current document.
CTRL and H Displays the Replace dialogue box.
CTRL and I Italic text.
CTRL and J Full Justification.
CTRL and K Create Hyperlink
CTRL and L Left Alignment
CTRL and M Tab
CTRL and N Creates a new document.
CTRL and O Displays the Open File dialogue box.
CTRL and P Displays the Print dialog box.
CTRL and R Fill Right Cell
CTRL and S Displays the Save dialog box.
CTRL and U Underline text
CTRL and V Pastes the copied item or text from the Clipboard into the current position in the document.
CTRL and X Cuts the item or text selected to the Clipboard.
CTRL and Y Redo the last undone action.
CTRL and Z Undoes the last action
Keyboard Shortcuts (Microsoft Windows)
1. CTRL+C (Copy)
2. CTRL+X (Cut)
3. CTRL+V (Paste)
4. CTRL+Z (Undo)
5. DELETE (Delete)
6. SHIFT+DELETE (Delete the selected item
permanently without placing the item in the Recycle Bin)
7. CTRL while dragging an item (Copy the selected item)
8. CTRL+SHIFT while dragging an item (Create a shortcut to the selected item)
9. F2 key (Rename the selected item)
10. CTRL+RIGHT ARROW (Move the insertion point to the beginning of the next word)
11. CTRL+LEFT ARROW (Move the insertion point to the beginning of the previous word) 12. CTRL+DOWN ARROW (Move the insertion point to the beginning of the next paragraph)
13. CTRL+UP ARROW (Move the insertion point to the beginning of the previous paragraph)
14. CTRL+SHIFT with any of the arrow keys (Highlight a block of text) SHIFT with any of the arrow keys (Select more than one item in a window or on the desktop, or select text in a document)
15. CTRL+A (Select all)
16. F3 key (Search for a file or a folder)
17. ALT+ENTER (View the properties for the selected item)
18. ALT+F4 (Close the active item, or quit the active program)
19. ALT+ENTER (Display the properties of the selected object)
20. ALT+SPACEBAR (Open the shortcut menu for the active window)
21. CTRL+F4 (Close the active document in programs that enable you to have multiple documents opensimultaneously)
22. ALT+TAB (Switch between the open items)
23. ALT+ESC (Cycle through items in the order that they had been opened)
24. F6 key (Cycle through the screen elements in a window or on the desktop)
25. F4 key (Display the Address bar list in My
Computer or Windows Explorer)
26. SHIFT+F10 (Display the shortcut menu for the selected item)
27. ALT+SPACEBAR (Display the System menu for the active window)
28. CTRL+ESC (Display the Start menu)
29. ALT+Underlined letter in a menu name (Display the corresponding menu) Underlined letter in a command name on an open menu (Perform the corresponding command)
30. F10 key (Activate the menu bar in the active
program)
31. RIGHT ARROW (Open the next menu to the right, or open a submenu) 32. LEFT ARROW (Open the next menu to the left, or close a submenu)
33. F5 key (Update the active window)
34. BACKSPACE (View the folder onelevel up in My Computer or Windows Explorer)
35. ESC (Cancel the current task)
36. SHIFT when you insert a CD-ROMinto the CD-ROM drive (Prevent the CD-ROM from automatically playing)

Dialog Box - Keyboard Shortcuts
1. CTRL+TAB (Move forward through the tabs)
2. CTRL+SHIFT+TAB (Move backward through the tabs)
3. TAB (Move forward through the options)
4. SHIFT+TAB (Move backward through the options)
5. ALT+Underlined letter (Perform the corresponding command or select the corresponding option)
6. ENTER (Perform the command for the active option or button)
7. SPACEBAR (Select or clear the check box if the
active option is a check box)
8. Arrow keys (Select a button if the active option is a group of option buttons)
9. F1 key (Display Help)
10. F4 key (Display the items in the active list)
11. BACKSPACE (Open a folder one level up if a folder is selected in the Save As or Open dialog box)

Microsoft Natural Keyboard Shortcuts

1. Windows Logo (Display or hide the Start menu)
2. Windows Logo+BREAK (Display the System
Properties dialog box)
3. Windows Logo+D (Display the desktop)
4. Windows Logo+M (Minimize all of the windows)
5. Windows Logo+SHIFT+M (Restorethe minimized windows)
6. Windows Logo+E (Open My Computer)
7. Windows Logo+F (Search for a file or a folder)
8. CTRL+Windows Logo+F (Search for computers)
9. Windows Logo+F1 (Display Windows Help) 10. Windows Logo+ L (Lock the keyboard)
11. Windows Logo+R (Open the Run dialog box)
12. Windows Logo+U (Open Utility Manager)
13. Accessibility Keyboard Shortcuts
14. Right SHIFT for eight seconds (Switch FilterKeys either on or off)
15. Left ALT+left SHIFT+PRINT SCREEN (Switch High Contrast either on or off)
16. Left ALT+left SHIFT+NUM LOCK (Switch the
MouseKeys either on or off)
17. SHIFT five times (Switch the StickyKeys either on or off)
18. NUM LOCK for five seconds (Switch the
ToggleKeys either on or off)
19. Windows Logo +U (Open Utility Manager)
20. Windows Explorer Keyboard Shortcuts
21. END (Display the bottom of the active window)
22. HOME (Display the top of the active window)
23. NUM LOCK+Asterisk sign (*) (Display all of the subfolders that are under the selected folder)
24. NUM LOCK+Plus sign (+) (Display the contents of the selected folder)

MMC Console keyboard shortcuts

1. SHIFT+F10 (Display the Action shortcut menu for the selected item)
2. F1 key (Open the Help topic, if any, for the selected item)
3. F5 key (Update the content of all console
windows)
4. CTRL+F10 (Maximize the active console window)
5. CTRL+F5 (Restore the active console window)
6. ALT+ENTER (Display the Properties dialog box, if any, for theselected item)
7. F2 key (Rename the selected item)
8. CTRL+F4 (Close the active console window. When a console has only one console window, this shortcut closes the console) Remote

Desktop Connection Navigation

1. CTRL+ALT+END (Open the Microsoft Windows NT Security dialog box)
2. ALT+PAGE UP (Switch between programs from left to right)
3. ALT+PAGE DOWN (Switch between programs from right to left)
4. ALT+INSERT (Cycle through the programs in most recently used order)
5. ALT+HOME (Display the Start menu)
6. CTRL+ALT+BREAK (Switch the client computer
between a window and a full screen)
7. ALT+DELETE (Display the Windows menu)
8. CTRL+ALT+Minus sign (-) (Place a snapshot of the active window in the client on the Terminal server clipboard and provide the same functionality as pressing PRINT SCREEN on a local computer.)
9. CTRL+ALT+Plus sign (+) (Place asnapshot of the entire client window area on the Terminal server clipboardand provide the same functionality aspressing ALT+PRINT SCREEN on a local computer.)

Microsoft Internet Explorer Keyboard Shortcuts

1. CTRL+B (Open the Organize Favorites dialog box)
2. CTRL+E (Open the Search bar)
3. CTRL+F (Start the Find utility)
4. CTRL+H (Open the History bar)
5. CTRL+I (Open the Favorites bar) 6. CTRL+L (Open the Open dialog box)
7. CTRL+N (Start another instance of the browser with the same Web address)
8. CTRL+O (Open the Open dialog box,the same as CTRL+L)
9. CTRL+P (Open the Print dialog box)
10. CTRL+R (Update the current Web page)
11. CTRL+W (Close the current window)
ComputersRe: 100 keyboard shortcuts and The A - Z Of All Microsoft Shortcuts by demand1982(op): 11:14pm On Jul 25, 2014
Better still, maybe this will be more clearer;

CTRL A select all
CTRL B Bold
CTRL C Copy
CTRL D Fill Down Cell
CTRL E Centre Alignment.
CTRL F find CTRL G go to current
CTRL H Replace
CTRL I Italic
CTRL J Full Justification.
CTRL K Create Hyperlink
CTRL L Left Alignment CTRL M Tab
CTRL N new page
CTRL O Open
CTRL P Print
CTRL R Fill Right Cell
CTRL S Save CTRL U Underline
CTRL V Paste
CTRL X Cut
CTRL Y Redo
CTRL Z Undo
Computers100 keyboard shortcuts and The A - Z Of All Microsoft Shortcuts by demand1982(op): 11:11pm On Jul 25, 2014
CTRL and A Selects all in the current document.
CTRL and B Bold text.
CTRL and C Copies the item
CTRL and D Fill Down Cell
CTRL and E Centre Alignment.
CTRL and F Displays the Find dialog box, to search the current document.
CTRL and G Displays the Go to dialog box, to go to a specific location in the current document.
CTRL and H Displays the Replace dialogue box.
CTRL and I Italic text.
CTRL and J Full Justification.
CTRL and K Create Hyperlink
CTRL and L Left Alignment
CTRL and M Tab
CTRL and N Creates a new document.
CTRL and O Displays the Open File dialogue box.
CTRL and P Displays the Print dialog box.
CTRL and R Fill Right Cell
CTRL and S Displays the Save dialog box.
CTRL and U Underline text
CTRL and V Pastes the copied item or text from the Clipboard into the current position in the document.
CTRL and X Cuts the item or text selected to the Clipboard.
CTRL and Y Redo the last undone action.
CTRL and Z Undoes the last action
SportsRe: Brazilian Star Neymar's Brain On Auto Pilot by demand1982(op): 1:40pm On Jul 25, 2014
this is the first time am learning that someone's brain could be on auto pilot. Thank God for the FIFA world cup. Hahahhaahaha
SportsBrazilian Star Neymar's Brain On Auto Pilot by demand1982(op): 1:33pm On Jul 25, 2014
Brazilian superstar Neymar's brain activity while dancing past opponents is less than 10 percent the level of amateur players,suggesting he plays as if on auto-pilot, according to Japanese neurologists.

Results of brain scans conducted on Neymar in
February this year indicated minimal cerebral
function when he rotated his ankle and point to the Barcelona striker's wizardry being uncannily natural.
"From MRI images we discovered Neymar's brain activity to be less than 10 percent of an amateur player," researcher Eiichi Naito told AFP on Friday.
"It is possible genetics is a factor, aided by the type of training he does.
" The findings were published in the Swiss journal Frontiers in Human Neuroscience following a series of motor skills tests carried out on the 22-year-old Neymar and several other athletes in Barcelona in February this year.
Three Spanish second-division footballers and two top-level swimmers were also subjected to the same tests, added Naito of Japan's National Institute of Information and Communications Technology.
Naito concluded in his paper that the test results "provide valuable evidence that the football brain of Neymar recruits very limited neural resources in the motor-cortical foot regions during foot movements".
Asked whether Neymar's Barcelona teammate
Lionel Messi or Real Madrid's Cristiano Ronaldo
might display similar test results, Naito said: "It is fair to assume they would show similar levels given their footwork and technique."
Naito told Japan's Mainichi Shimbun newspaper: "Reduced brain activity means less burden which allows (the player) to perform many complex movements at once. We believe this gives him the ability to execute his various shimmies."
Neymar carried the hopes of host nation Brazil on his shoulders at the recently ended World Cup but his involvement ended in tears as he fractured a vertebra in the 2-1 quarterfinal victory over Colombia.
Without their talisman, who had scored four goals in the tournament, Brazil suffered their most humiliating defeat ever when they were pulverised 7-1 by eventual champions Germany in the
semifinal.

mobi.supersport.com/football/spain/news/140725/Neymars_brain_on_autopilot
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 1:12pm On Jul 25, 2014
hareerat11218: Let the Lawmakers in Nasarawa state try to go ahead with the impeachment saga. Then i swear to God, that is when Nigerian revolution will start and we the people of Nasarawa state will be the first people to start killing our politicians and we will start from the Lawmakers
hmmm that is you careless whether Al Makura has a case to answer or not? Do not forget that violence only begets violence.
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 7:59am On Jul 25, 2014
jericco1: By giving each Lawmaker a bag of money
please you can still tell the house how much
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 7:58am On Jul 25, 2014
disloman: Mi no believe this story oooo.Till dem stop impeachment.No b say later,e. Go talk say him(GEJ) tried his best but d house don made up their minds oooo.No b naija politics.Taaaaa.
lolxxxxx typical Nigerian
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 6:40am On Jul 25, 2014
melifew213: Al Makura must go. Gej pls don't intervene
for you to sound like this, am thinking you are from Nassarawa state and only who is wearing the shoe knows exactly how much it is paining him. But the least youcan do is give GEJ reasons no to intervene.
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 6:31am On Jul 25, 2014
san316: Based on the report, there are no indications that he went to save Ta'al. If eventually he went 4 dat reason, then Ta'al must hv made a deal with him (either cm to PDP or deliver ur state to me in 2015 or be a pdp mole in APC). Stinking politricking in Nigeria.
lolxxxxx I think the President is not so foolish to make a deal with any opposition APC gov this time around as 2015 will be different from 2011 that ACN did to all vote for the president and clinch the gov in return.
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 6:27am On Jul 25, 2014
NIGERIALOLoCOM: Will this move by our presido go down well with Labaran Maku? huh grin
are you now saying that Maku is the architect of the impeachment?
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 6:24am On Jul 25, 2014
kokoA: If the guy has committed an impeachable offence then he should go naw.. These politicians don't have the interest of the people at heart at all.. Smh.. So if you are Mr. President's friend then you are free from punishment, no matter what wrong you do? GEJ should know that presidential elections do not depend on the number of governors in support of you nor the number of states your party controls but on the popularity of the contestants.. A new party like the defunct CPC who controlled no state as at 2011 was able to pull over 12million votes during the last presidential election.. Impeachment or no impeachment of opposition governors is irrelevant to how people will vote.. It Al'makura is found guilty, he should be kicked out!
reasonable analysis from an unbiased mind
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 11:51pm On Jul 24, 2014
emmyrichie: That guy 'Mr. President' might be wrong on this move.
The dude (Almakura) must have done something wrong to warrant impeachment.

Why's Mr. President trying to save a corrupt man who stole, embezzled, misappropriated the people's fund(s)?
if only he would give us any reason at all, it is going to be "national interest." lolxxxx
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 11:48pm On Jul 24, 2014
emmyrichie: grin Guy you are wicked... Btw, why's your moniker ratiken, are you a rat poison?
very strong adjective you used there mahn!
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 11:10pm On Jul 24, 2014
dragan: He's not really that much of an experienced Politician, he's just a wealthy businessman that decided to try and save the State from the crap it went through with two PDP governors and as far as i know he's done well with the small budget and the debt on the state. This whole thing is because of that Nigerian Mentality of some tribes in the state believing its their turn to rule, and he kind of recklessly promised to serve for 1 term.

But just like I expected guys like Labaran Maku wouldn't be too happy about this since the Deputy will take over and he'll just have another PDP candidate to go against and he'll have the upper hand as Governor if Al-Makura is impeached.

Summary - Al-Makura is a good man that's done better than all the 12 years of former PDP governors, the Legislators have been frustrating his efforts for the last 3 years and no other PDP candidate can defeat him in a fair election unless they impeach him or start some ethnic or religious tension in the state (like they tried to with the Ombatse crap and every other thing that happens that's never on the news).
hmm what a take!
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 8:24pm On Jul 24, 2014
Sec5: I don't think d President is right to stop a Democratic process if d gov has committed impeachable offence unless if d impeachment plan is a witch hunt.
I agree that no president has the right to truncate any democratic process, but what if he studies the mood of the nation and finds a way to douse the tensions here and there? Especially id he can reach out. I do not see any thing wrong in that aspect.
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 8:17pm On Jul 24, 2014
danot1030: Dat is leadership in display. A true leader don't watch his house scatter on the bases of affinity cos he sees himself as a leader to both on his side and those not. He is not the type that want one to be destroy for him to gain, a leader's gain is premise on credibility. Kudos to GEJ, I give u this one.
why am giving you a thumbs -up? Are you in any leadership position presently? Cause as a leader myself, I know the import of your statement.
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 8:11pm On Jul 24, 2014
egift: Jonathan, stage-managing trouble in Nigeria since 1st October, 2010.
really
PoliticsRe: Jonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 7:31pm On Jul 24, 2014
seanet02: The mofo is going back to PDP.
please who is the mofo and what does it mean
PoliticsJonathan Moves To Save Al-makura, Meets Nasarawa Lawmakers by demand1982(op): 7:21pm On Jul 24, 2014
President Goodluck Jonathan on Thursday met behind closed-doors with six members of the Nasarawa State House of Assembly.

The meeting was believed to be the President’s way of intervening in the impeachment process that the lawmakers had instituted against the state governor, Tanko Al-Makura.

Al-Makura had met with the President over the weekend in his bid to stop his removal from office.

The members of the Assembly, who met with Jonathan on Thursday, were led by their Speaker, Musa Muhammed.

The Deputy National Chairman, South, of the Peoples Democratic Party, Uche Secondus, also attended the meeting.

The National Chairman, Adamu Muazu, is currently on lesser Hajj in Saudi Arabia.

Muhammed however told State House correspondents at the end of the parley that the meeting was a private one.

When pressed further to disclose whether the meeting has changed the situation in the state, the Speaker said he did not have the mandate of the Assembly to speak with journalists.

He said only the Chairman of the House Committee on Information was mandated to speak to journalists.

“It is a private visit. We are here to see the President on a private visit. I do not have the mandate of the assembly to address the press. We have the Chairman of the House Committee on Information, who we have agreed should be talking on our behalf,” he said.

When asked whether the Assembly was under pressure from the Presidency or any other quarters to drop the impeachment process, Muhammed asked, “Who is putting pressure on who?”

Secondus, who came out of the President’s office a few minutes after the lawmakers, claimed he did not come with them.

He said he arrived the Presidential Villa before them.
www.punchng.com/news/jonathan-moves-to-save-al-makura-meets-nasarawa-lawmakers/
PoliticsRe: If Buhari Had Been Killed , The North Would Have Razed Nigeria Down by demand1982: 6:43pm On Jul 24, 2014
@Op what do you mean north razing Nigeria down?
Next use the statement " ...the north-west or parts of the north would have been thrown into chaos."
Nigeria is far bigger than one man or what some call "demi-god."
PoliticsRe: President Jonathan Calls Buhari Over Bomb Blast by demand1982(op): 4:16pm On Jul 24, 2014
chison89: Ahahahaha
I hail o oga gej
correct that is the way it should be.
PoliticsPresident Jonathan Calls Buhari Over Bomb Blast by demand1982(op): 3:55pm On Jul 24, 2014
President Goodluck Jonathan has spoken to Gen. Buhari on the phone over the bomb attack that nearly clamed his life TheCable.ng understands.
This telephone conversation came a day after Jonathan and Buhari's camp had exchanged hot words over the impeachment proceedings against some opposition governors.
TheCable.ng learnt that the president put a call through to Buhari on wedneaday evening to express his sympathy with the former head of state.
Details of the conversation are still schetchy, but TheCable was informed that Jonathan promised a thorough investigation into the incident.
The conversation was said to be "warm, cordial and sincere" by a source in the know.

Source www.thecable.ng

www.thecable.ng/exclusive-jonathan-calls-buhari-over-blast
PoliticsRe: The Biggest Lie And Propaganda Of The Century In Rivers State by demand1982(op): 8:20pm On Jul 23, 2014
@stanech lolxxxxxx
PoliticsRe: The Truth About Amaechi Monorail Project With Pictures by demand1982: 2:06pm On Jul 23, 2014
hazekctravels: More
thanks man as this will go a long way
PoliticsRe: The Biggest Lie And Propaganda Of The Century In Rivers State by demand1982(op): 1:58pm On Jul 23, 2014
noblezone: My brother, I thought of going over there, use camera to do a video coverage of the entire rail while of foot!
The whole length may take like 10 mins walk, but you see bros, anyone who does that, might not come back alive!

My kids are too young to loose me!

What the OP said has no iota of lie in it!
thank you my for your understanding why One could not go into a snapping spree for fear of the unknown.
PoliticsRe: The Biggest Lie And Propaganda Of The Century In Rivers State by demand1982(op): 8:37am On Jul 23, 2014
jobless ke! Who sent that liar to come up here and tell gullible Nairalanders and Nigerians fat lies. Please rephrase your comment to fit the appropriate person. No sense!
PoliticsThe Biggest Lie And Propaganda Of The Century In Rivers State by demand1982(op): 8:23am On Jul 23, 2014
I liked Gov Amaechi for his monumental achievements during his first term. However, there is now a lull in performance and a total opposite in his second term in Rivers state today.
But the biggest lie and propaganda today is the mono rail progect in the city of Port Harcourt close to government house.
I live outside Port Harcourt in Omagwa Town, some few KM off PH buh always having one thing or the other to do in Port Harcourt.
Ever since the news of the test-run of the much awaited mono rail went viral in the social media yesterday, I had to relocate to Port Harcourt to see things for myself firsthand.
From Omagwa yesterday morning around 9:00AM, I came to stay with a cousin in Station road almost directly opposite the mono rail project.
From 10:00AM I started asking questions and and visiting the project area waiting to see this rail move but to no avail. All I saw was a head( not two or three oh as we saw on nairaland yesterday) couch with no engine just hanging on the free rail line immobile till around 2:00PM.
Took an hour break and came back around 3:00PM and left by past six thinking maybe they will run it later in the evening buh was disappointed still.
Came as early as 6:00AM today to the site where this rail is hanging, as in fact am there now to further confirm to you guys that there is not even a sound of testing from any engine of any mono rail in PH. I was was told that that rail has been hanging like that for the past three days without changing coordinates.
In conclusion, this is the biggest lie and propaganda in PH recently as the guy who posted that HYPE yesterday did a great disservice to Rivers people by assaulting our intelligence and abused the previlege offered him by Nairaland.
HealthScientists Discover New Exciting Drug That Flushes Out HIV by demand1982(op): 11:26am On Jul 22, 2014
Scientists say they have made an
"exciting" step towards curing HIV by
forcing the virus out of hiding.

HIV can become part of someone's DNA and lie dormant for decades, making a cure impossible. Early stage research in six people, reported at the Aids 2014 conference, shows that low-dose chemotherapy can
awaken the virus.
Experts said it was a promising start, but it was unlikely the drug would work on its own to cure HIV. Anti-viral drugs can drive HIV down to
undetectable levels in the bloodstream, meaning people who are HIV-positive can have a near-normal life expectancy.
But there is problem.
HIV can incorporate its DNA into our own, where it lies beyond the reach of drugs and the immune system - it is known as the HIV reservoir.
When drug treatment stops, the virus can leap out of the reservoir and renew its assault.
International research is aimed at
flushing the virus out of its reservoirs. A team at Aarhaus University in Demark tried using a chemotherapy drug, romidepsin, which is used in lymphoma.
Six HIV patients with undetectable levels of the virus were enrolled into trial.
They each received a reduced dose of
romidepsin once a week for three weeks. There was a noticeable jump in viral levels in the blood in five of the patients.
One of the scientists involved, Dr Ole
Sogaard, told the BBC: "Every step forward is always exciting, and I think this is quite important." He said there had been a lot of scepticism
about the drug being potent enough. "We've shown it is possible to kick the virus out of the cells, the next step is to actually kill the cells.
"The trial now moves into a new phase which combines the romidepsin with something to enhance the immune system and in our case this is an HIV vaccine.
" Side-effects were those normally
associated with chemotherapy, including fatigue.
Difficult challenges HIV viruses emerging from a hijacked cell There are still many challenges ahead. The team cannot say what proportion of
cells hiding HIV are being activated by
romidepsin.
Another looming question is which
reservoirs are being successfully targeted.
HIV can hide in immune cells in the blood, but there are bigger reservoirs in the gut and central nervous systems and it is not clear whether they are activated by the blood-based chemotherapy.
"We know it's a step forwards, but we
don't know how big, it might just be a
single step or it could be a great leap
forward," Dr Sogaard added. Romidepsin works by "relaxing" tight
coiled up bundles of DNA. This exposes the hidden HIV genetic code and leads to the production of new viruses.
Dr Andrew Freedman, a reader in
infectious diseases at Cardiff University, told the BBC: "As a proof of concept it does look promising. "The search for a cure is very much on, it's
not going to be easy and it's unlikely a single drug like this would be sufficient.
"There's a lot of doubt it would be enough to deplete the reservoir completely. "Most people think a single approach will not be enough, a drug like this perhaps needs to be combined with vaccines or even gene-therapy."

huh??......bbc.com
PoliticsRe: Did Adamawa People Vote APC Why Blame PDP For Doing The Needful by demand1982(op): 10:51pm On Jul 17, 2014
Firstly, adamawa people did not elect their ex-governor Nyako under the APC platform rather they freely gave their mandate to the PDP.

And when he left for the APC he never bothered to consult the people that voted him and before you would say jack bauer he has taken their popular will to another platform for whatever reasons he may have had.

Not that I support impeachment as a tool for our politicians to wield like the Harry Potter's wand at the opposition but when it is done to correct an anomaly then I support it.

What the PDP lawmakers only did was to take back what rightfully belonged to it as they only did the needful on NYAKO and reclaimed their mandate so that Nyako can go now and contest freely on the platform of the APC and SEE IF HE WILL WIN adamawa state back for APC.

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