₦airaland Forum

Mad oh!

GreenArrow1:
Why you stop for bridge? It think say we go reach fly-over and those big big round-abouts.

Talk oo abeg

longetivity:
if i talk now............

you have a very good point. nice

Many Ladies have wondered if sex can actually increase their butt size. Guys too have actually have this same feeling, seeing a beautiful looking very slim and all of a sudden boom she is looking bigger, butts are now looking bigger and also boobs are looking bigger. Here we are going to focus more on the butt and most importantly the sex position that will help increase their butt size. This is indeed a fact and it has been seen to work very well in many cases except other wise.

People who like having sex and a big butt often wonder if it's possible for one to increase their butt size by having sex. Of course, it's usually a random, passing thought, and little much attention is paid to it. Still, if you wonder if you can increase the size of your butt, you should know that the jury is relatively divided here. Big butts and smaller waist seem to be today's trend.

When it comes to booty growth, the position you have sex in plays a huge part into whether or not it happens.

1. Position for a bigger butt: Classic Missionary

Most people tend to have sex in the classic missionary position. However, you only work your core muscles, not your butt muscles. This is especially true if you’re the one on top – be it man or woman. If you want the missionary position to work your butt, you’ll need to spread your legs out as far as you can and allow the glutes to do the work. Look up image under source below


2. Position for a bigger butt: Doggy Style

Many couples like to venture outside the realm of classic missionary sex, opting for the doggy position. If this happens to be you, it’s important you understand that the muscles in your butt and hips are doing most of the work. Again, your glutes are going to get a workout, but only if you stick your butt up into the air.


3. Position for a bigger butt: Cowgirl


While the missionary and doggy style positions are good, the cowgirl position is far better. It gives not only your butt a workout but your legs too. You’ll need to balance your legs on the floor or bed (your choice here), which will work your legs, hips and butt. While you do all the work, you have to remember you’re getting in a fairly decent but workout. Most importantly, the position is rather fun to try.

4. Position for a bigger butt: Against the Wall – Full Body Workout

If you want a full-body workout, you need to make use of your wall. No matter what wall you use, you engage your entire core and, when that happens, you engage in other parts of your body. The core stimulates the muscles in your butt because you have to remain standing. Your back and neck muscles become engaged. Your partner will need to use their arms to hold you up, which means they get a core, butt and leg work out too.

5. Position for a bigger butt: The Bridge

If you’re the adventurous type, consider the "bridge" position. Don’t try this if you have weak muscles or don’t have the determination to carry it out. However, it will give your butt muscles a major workout. What do you do? Put your legs and arms on the floor (or bed) like a table is. Your back should be facing the floor, your stomach toward the sky and you’ll be holding your butt.

Now, for you to have a better understanding of this message click on the source link below and see full images.

Source: http://afrohits.com.ng/news-top-sex-position-that-can-increase-your-butt-size-officially-for-ladies/

Funny you. you know it wont be appropriate now.

Why the face?

Smoking is a serious risk factor for many infections and respiratory illnesses.

Studies have also shown that smokers are more likely to develop COVID-19 disease than non-smokers.

Covid-19 is a respiratory disease that affects the lungs. Smoking impairs lung function and makes it difficult for the body to fight COVID-19 and other diseases.

Smoking is a risk factor for non-communicable diseases such as cardiovascular disease, cancer, respiratory disease and diabetes, and puts people at risk for COVID-19.

Existing research shows that smokers are at risk for more serious illness and death.

Although there is currently insufficient information to confirm any link between tobacco or nicotine in the prevention or treatment of COVID-19, the WHO is constantly reviewing the link between tobacco use and COVID-19 and strongly recommends quitting smoking. These include chewing gum, nicotine cracking patches, nicotine replacement therapy, and more.

Within 3 minutes of quitting nicotine, your heart rate and blood pressure drop, and after 3 hours, your blood carbon monoxide levels return to normal.

After 3 to 6 weeks, blood pressure is regulated and lung function improves, and after 4 to 3 months, coughing and shortness of breath are reduced.

Pharmahub_NG


Source: http://afrohits.com.ng/smoking-covid-19/

By Lindsey Robertson

You may grimace at the thought of going to the gym, but when the thought of acrobatic sex enters your mind, there’s a decent chance your eyes probably light up. Any why not? The act of sex is a reward unto itself, whereas going to the gym often only feels good once it’s over.
Perhaps it’s time we started melding these two physically exhausting realities together and letting our sex life slowly turn into … our sex-ercise life??

It’s so crazy, it just might work!

After all, a half hour of intense sex can burn around 207 calories — so why not up the ante in the bedroom and sculpt your bod while you’re getting off?

Here are a few especially *ahem* “active” positions (helpfully demonstrated by wooden figurines) to get your sexual creativity flowing, along with the particular parts of the body that they exercise and benefit.

And who knows? Combining your sex life with your gym time may be so efficient, that you’ll have more free time that you know what to do with! (But really, who are we kidding, we all know free time is for reading and masturbating.).


1. The Half-Pushup.

Who says sex only works your lower body? Sprawl out across the bed until your arms touch the floor (supporting about half of your weight), then have him kneel on the bed and take you from behind. Not only will you get some choice deep-penetration, but your arms will get a nice little workout from holding this pseudo-plank position.

2. The “V” for “Victory”

This position is similar to missionary, except that your legs are pointing straight out on either side of his head, creating a “V” shape. Your lower back is slightly raised as well, to give him abetter angle. This particular position will make your center of gravity especially happy, and your glutes and thighs will definitely feel the burn before you *ahem* finish.

3. The Face-To-Face

Just because you’re both laying on your sides doesn’t mean that this position can’t be a workout! Tell him to take a reprieve from being in the driver’s seat, and hook your leg outside of his to grind against him with full control. Not only is this a cool sensation, but it will also force your core muscles to engage. Your abs (and your lady-parts) will thank you later.

4. The Stand And Deliver

This position is certainly not for the faint of heart — but if you’re up to challenge, it can be a fun and rewarding (*wink wink, nudge nudge*) workout. Have him stand and hold you while you jump up and wrap your legs around his torso before slowly sliding down onto his penis. While it can be difficult to get a good rhythm in this position, they key is to clasp your legs tightly at all times and use your hands on his shoulders as leverage.

5. The Cuddle Puddle

This position’s cute name belies how physically engaging it actually is. While some mightbe tempted to use the Cuddle Puddle for the “slow-burn” portion of coitus, figuring out how to grind away in this sexy, seated position will definitely burn a few calories — and possibly your bedsheets. Face your partner and straddle him, leaving your legs out straight on either side. This position will force you to use your thighs and core to really get a good rhythm going. If you find that it’s too exhausting, don’t be afraid to lean on one of your arms for support.

6. The Reverse Grinder

Similar to the Cuddle Puddle, except you’re facing away from your partner, with your legs out in front. Usually it helps to bend your legs a bit and use them for support during this one — otherwise your partner is left to do all the work. This is an especially great position for working out your butt and thighs, as you’re definitely going to have to engage them a bit to properly ride your (very lucky) partner.

7. The Triangle

For this doozy, your partner kneels at the edge of the bed while you lift your torso and hook your legs over his shoulders. Unlike the “V for Victory” position, the emphasis here is on lifting your butt and torso — so that you not only get deeper penetration, but you get a pretty enjoyable core workout, too.

8. The Cobra

If you’re looking for the world’s most indulgent shoulder workout (I don’t know why you would specifically be looking for that, but just work with me, here), then this particular sexual move is definitely for you. This position essentially involves your partner taking you from behind while you keep your legs together and your pelvis lowered, using your arms to lift and support your upper torso. Keep your legs together like this will give you some freakin’ amazing sex (regardless of his size), while also giving your oft-neglected shoulders a workout they won’t soon forget.

9. The Hanging Branch

Yes, this is an MouthAction position which pretty much focuses exclusively on your pleasure. If your partner has a problem with that, then maybe you should tell him to NOT LET THE DOOR HIT HIM IN THE ASS ON THE WAY OUT.

Moving forward. This position is a tad acrobatic, so definitely don’t attempt it if you aren’t feeling limber. Remember: stretching is your friend! For this move, your partner lays across the bed while you lay with your torso on the floor and your feet firmly planted above you on the bed. From here, he should have pretty easy access to all of your buttons.

This position will not only give you some pretty wild MouthAction, it will also force you to essentially hold an elevated bridge position for an extended period of time. Which is no simple task — regardless of whether you’re in a yoga class, or in the bedroom.

10. The Impossible 69



Okay, look: there is almost no way you should attempt this move. At least not without a spotter. But, if you can successfully complete this standing position, you will have earned my utmost respect — and will have probably unlocked some super sexual achievement or something.

Just please, for the love of God, make sure you’re surrounded with soft pillows, okay?

To see all the positions for a better understanding visit the source below.

Source: https://afrohits.com.ng/11-sex-positions-that-are-better-than-basically-any-gym-workout/

Scientists have been investigating a plethora of drugs that may be repurposed to fight COVID-19. The hope is that of the 15 drugs listed here, some could be discovered as a treatment for this disease.


1. Chloroquine and Hydroxychloroquine

The drugs being tested for re-purposing to treat COVID-19 tend to fall into two categories: those that target the viral replication cycle, and those that aim to control the symptoms of the disease. The aminoquinolones and hydroxychloroquine are polymerase inhibitors classically used as anti-malarial medications. In malaria, they inhibit heme polymerase, causing the accumulation of toxic heme in the parasite, which leads to its death. In COVID-19, it is thought that the drugs keep the virus out of host cells by blocking glycosylation of host receptors and breaking down the production of viral proteins by inhibiting endosomal acidification.

However, although initial studies looked promising, there were flaws in the study design, says James Cutrell, an infectious-disease researcher at the University of Texas Southwestern Medical Center and author of a recent review in the Journal of the American Medical Association on possible COVID-19 medications. Another randomized study of 30 patients in China that came out around the same time found that they provided no benefit over standard treatment, and an observational study, published in the New England Journal of Medicine, hydroxychloroquine administration was not associated with a reduction in death among hospitalized patients with COVID-19. Still, the drugs are the subject of more than 30 different clinical trials in the USA alone.

2. Lopinavir and Ritonavir

The human immunodeficiency virus protease inhibitors lopinavir and ritonavir work against coronaviruses via inhibition of 3-chymotrypsin-like protease. Invitro tests have shown the drugs to be effective against SARS-CoV-1 and the coronavirus that causes Middle East respiratory syndrome, but no tests have confirmed that same mechanism of action against SARS-CoV-2. A randomized open-label trial in China of some 200 hospitalized patients did not find the drug combination to be more effective than standard care, but further clinical trials are pending. According to the review in the Journal of the American Medical Association, the drugs may have limited appeal because of side effects, most notably increased nausea and diarrhea and increased risk for liver damage, all of which could exacerbate the signs of COVID-19. In a randomized controlled study published in the New England Journal of Medicine, there was no association between treatment of patients with severe COVID-19 with lopinavir–ritonavir and reduction in SARS-CoV-2 viral load or significant clinical benefit. Another trial on people with mild COVID-19 shows reduced time of viral shedding, reduced time to alleviation of symptoms and reduced hospital stay in a group with lopinavir, ritonavir, IFN-B and ribavirin, as compared to a group receiving lopinavir and ritonavir alone.

2. Nafamostat and camostat

Nafamostat and camostat are serine protease inhibitors both approved in Japan for use against pancreatitis in humans. Camostat was previously found in vitro to block the entry of SARS-CoV by acting as an antagonist to the serine protease TMPRSS2, and researchers believe both nafamostat and camostat could have a similar effect in inhibiting SARS-CoV-2. In vitro, both have been found to block the entry of SARS-CoV-2 into cells, although one preprint study reported that nafamostat inhibited viral cell entry with an efficiency roughly 15-fold higher than that of camostat.

These drugs are undergoing phase 2 and phase 2/3 clinical trials in the USA and Japan for their effectiveness against COVID-19, the primary outcome of which will be time to clinical improvement for nafamostat and reduced viral load after treatment for camostat.

“These drugs are quite old, they’re well studied, they have known targets that are exactly the same protease that the virus uses,” says Anton Yuryev, professional services director at Elsevier, who has done screenings for possible COVID-19 drug treatments.


3. Famotidine

The over-the-counter H2 receptor antagonist heartburn medication famotidine is also been investigated as a possible treatment, after Michael Callahan and colleagues in China reported that patients in Wuhan who happened to be taking heartburn medication seemed less likely to die from or to be intubated during severe COVID-19. These observations have been published as a preprint, but have yet to be peer-reviewed. Hospitals in New York are currently testing intravenous famotidine with hydroxychloroquine and are recruiting hundreds for a phase 3 randomized trial for patients with COVID-19 who have critical status.

The mechanism of action for famotidine is not clear at this time. Famotidine was thought to possibly bind a papain-like protease that is encoded by the SARS-CoV-2 genome and is known to be essential to the entry of SARS-CoV; however, none of the cell assay results so far support that hypothesis, says Robert Malone, a Virginia-based biodefense consultant working on the famotidine tests. Malone says his team is enthusiastic about the drug because of its low cost, low toxicity and bioavailability.


4. Umifenovir

Umifenovir is a small indole-derivative molecule licensed for use only in Russia and China as prophylaxis for influenza virus A and B and is thought by some to have broad-spectrum anti-viral properties, although the evidence of its beneficial effects for human health is still under debate.

Because it is a hydrophobic molecule that is thought to interact with both lipids and proteins, it is thought to achieve its direct-acting anti-viral and host-targeting properties by binding the viral lipid membrane and affecting cellular trafficking of the virus. A study comparing it to lopinavir/ritonavir found it to be more effective at reducing viral loads in patients. Another trial in preprint found neither treatment to be effective at improving outcomes for patients with mild to moderate COVID-19.


5. Nitazoxanide

Nitazoxanide is a thiazolide used as an anti-infective with efficacy in parasitic, bacterial and viral infections. In viral infections, such as infection with the coronavirus MERS-CoV, it acts by blocking maturation of the viral nucleocapsid N protein that promotes production of the viral particles. This drug is being tested in clinical trials against hydroxychloroquine and with another anti-parasitic, ivermectin.


6. Ivermectin

Ivermectin is a lipophilic macrolide usually used as a broad-spectrum anti-parasitic drug that also affects many invertebrates. In parasites, it acts by binding glutamate-gated chloride ion channels, which leads to depolarization of the cells and paralysis or death of the parasite. When directed against COVID-19, is thought to work by binding and destabilizing cell-transport proteins used to enter the nucleus. In an observational multi-center study with some 1,400 patients that is still under review, administration of ivermectin was associated with a lower death rate (7% versus 21% in the control group) and shorter hospital stays. Fewer intubated patients died in the ivermectin group as well (7% versus 21%). At least two trials are currently recruiting participants to test the drug; one is a pilot study in India that will compare ivermectin to standard of care, and another study in Kentucky will test the drug along with hydroxychloroquine.


7. Corticosteroids

Researchers are also testing molecules to offset the potential ‘cytokine storm’ that leads to lung injury and acute respiratory distress syndrome (ARDS) in some patients. Along with efficacy, safety is the main concern with these types of drugs, says Cutrell, adding that immunomodulators can have negative downstream consequences, such as increasing the risk of other type of infections.

Chief among these immunomodulatory drugs being studied for treatment of COVID-19 are corticosteroids. These are well studied but are also one of the bluntest tools for muting the immune system.

These molecules inhibit the expression of many genes encoding inflammatory molecules. But long-term use is associated with cardiovascular disease and bone-density loss. A previous meta-analysis found that corticosteroids are associated with higher mortality in those with influenza pneumonia. One retrospective study in China found that its use in those who developed ARDS was associated with decreased death. A variety of clinical trials are ongoing.


8. Tocilizumab and sarilumab

In a retrospective study of some 200 patients with COVID-19, those experiencing severe forms of the illness had elevated levels of the inflammatory cytokine IL-6. It is thought that cytokine-release syndrome is involved in the exacerbation of severe reactions to the virus, causing ARDS even as viral loads diminish. A variety of drugs that block different cytokines are being tested in clinical trials, including tocilizumab and sarilumab, both monoclonal-antibody antagonists of the IL-6 receptor that are normally used to treat rheumatoid arthritis. The results of a randomized controlled study of tocilizumab appear to be promising, although the data have not been published yet. Preliminary results from a phase 2 study of sarilumab show some positive trends from drug administration in patient groups categorized as ‘critical’ but negative results in patients in the ‘severe’ group (those requiring oxygen supplementation but not intubation). The third phase of that trial is testing only its higher dose of the drug versus placebo in the critical group.

“I do think there may be a subset of patients who have this really exaggerated inflammatory response, that may be benefit from that, but we’ll need to watch these trials closely,” says Cutrell.


9. Bevacizumab

Researchers in China and Italy are recruiting for clinical trials to test bevacizumab, a monoclonal antibody that serves as a medication directed against the signaling protein VEGF (vascular endothelial growth factor) in a variety of cancer treatments. The drug suppresses tumors by inhibiting the growth of blood vessels that feed the tumor. By suppressing VEGF, this drug can also potentially reduce vascular permeability and thereby decrease the amount fluid entering the lungs of patients with COVID-19 who are suffering from ARDS.


10. Fluvoxamine

A surprising source of immunomodulation could be the antidepressant fluvoxamine, which is normally used to treat obsessive-compulsive disorder. Previous studies in animals found that this selective serotonin-reuptake inhibitor binds to the sigma-1 receptor to shut down the inflammatory cascade from the endoplasmic reticulum in cells.

Researchers are hoping to recruit some 150 people from Missouri and Illinois to participate in a randomized placebo-controlled trial. Patients with mild symptoms of COVID-19 will be mailed either the drug or a placebo, and doctors will monitor results remotely.

Caline Mattar, an infectious-disease researcher at the Washington University in St. Louis, says this trial also will be in outpatient setting, another advantage to the use of an oral medication such as fluvoxamine.

“It’s a drug that we have used in many patients and we know that it’s safe,” she says.


All of these drug repurposing studies are under the microscope of public scrutiny

For any of these drugs, researchers need solid clinical trials, but that is even more difficult with public scrutiny over readily available drugs.

Malone is anxious not to repeat the mistakes made with chloroquine and hydroxychloroquine, which became overhyped in a way that stymies clinical trials and supplies of the drug.

“We need to allow good science to be done before drawing conclusions,” says Malone.

He is also worried about finding the money to do those trials, especially when much of the funding is going toward the development of vaccines in what he considers to be an unrealistic timeline.

“One cannot raise capital when senior government officials are touting that a vaccine is going to be available in 12 to 18 months,” he says.

If repurposed drugs play a part in helping the public endure the pandemic, researchers do not have the luxury to try to build perfect compounds.

“Perfect is the enemy of the good, and we kind of have to work with what we have,” says Malone.

Leah Shaffer


Source: https://afrohits.com.ng/15-drugs-being-tested-to-treat-covid-19-and-how-they-would-work/

My world slowly crumbled, like a house built on a shaky foundation, which collapsed when heavy rain fell. His name is Tope.

Tope was a handsome young man with a promising future; though from a very poor family. He is as intelligent as a computer machine. He has this well-carved beards, that was always neatly shaved. It was always perfect as though his barber is made from heaven.

He is slender, tall and when he walks; he lifts one leg slowly, followed by the other, in a grand style. The scent of his perfume always sweet, making any girl want to be lost in his arms at all time.

Well, he was also the talk of the fellowship and every lady wanted him.

When he sings, the melody of his voice resonates with my heart. He came for me. I was so elated when he asked me out, it didn’t take weeks before I gave him a big YES. We were in love, everyone around us could testify that we were love birds.

Five months after we met, he took me to his house and introduced me to his family. They all welcomed and accepted me as his fiancee.

Time flies so fast, before you know it, we had graduated and we preparing for our marriage. The days were becoming very slow, I couldn’t wait for the day that I will walk down the aisle majestically with my heart throb. Preparations were ongoing.

Two days to my traditional marriage, I began to feel uneasy, but couldn’t place the nostalgic feeling.

It was unusual, I began to feel cold. I quickly dialled Tope’s number; he was not picking. I got scared that something must have happened to him. I rushed to the bathroom as though I was being chased by a kangaroo. I quickly showered and dressed up, forgetting to even apply powder not to talk of make-up on my face.

I rushed out of the house, still dialling Tope’s number. He wasn’t picking. I called his mum to ask if Tope was fine. She said “The last time I spoke to Tope was three days ago”.

I decided to go to his house. I could feel my heart pounding so fast, as if a pestle was being used to pound yam in my chest region.

When I got to his house. Blood stains greeted me on the corridor. I died twice. I began to shed tears and to scream “No! No!. It can’t be my Tope. My Tope must not die. As I screamed and ran inside his room guess what I saw.

I saw Tope and my best friend Tara [/b]struggling to put on their clothes, both were sweating.

As soon as I saw them struggling to cover themselves, I literally fainted.

I woke up on the hospital bed. My head ached as though someone was using pestle to pound it. I was trying so hard to understand why I was in a hospital.

Then the door opened, and I saw [b]Tope walked in. Immediately my memory came alive and I began to recount what had happened earlier.


I screamed and asked him to walk out. He came to my bed side. I was still screaming. A nurse walked in.

I was trying to tell her that I don’t want to see Tope but then my mouth was so heavy, all I could do was cry. Thank God the nurse understood. She politely asked him to leave, which he did.

Then she injected me with what seemed like a painkiller and immediately my worries disappeared like they never existed and I slept off like a baby…..

I woke up, everywhere was dark.

My memories came alive again, I began to remember all that transpired. And I asked myself questions that I could not answer…..

What did I do to Tope, to deserve this?

When did he start cheating on me with my best friend?

Why would Tara [/b]betray me??

Tara knows all my secret. [b]Tara is even supposed to be my chief bridesmaid.

How? When? Where?

While I was having all this thoughts? Something quickly flashed to my mind. I held my mouth to stop me from screaming……..

So all the signals I have been seeing, so this is what it meant?? I couldn’t believe it.

Do you want to know the signs, I had been seeing but never took it to heart?

Then watch out for Episode 2. It’s gonna be ghen ghen

Source: https://afrohits.com.ng/he-broke-my-heart-%f0%9f%98%ad%f0%9f%98%ad-episode-1/