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US Approves Once-a-day HIV Pill - Health - Nairaland

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US Approves Once-a-day HIV Pill by mkmyers45(m): 10:56am On Aug 29, 2012
A new pill to treat HIV infection -- combining two previously approved drugs plus two new ones -- has been approved for adults living with the virus that causes AIDS, US regulators said.
The single daily dose of Stribild provides a complete treatment regimen for HIV infection, the US Food and Drug Administration said in a statement, and is meant for people who have not already received treatment with other HIV drugs.

"Through continued research and drug development, treatment for those infected with HIV has evolved from multi-pill regimens to single-pill regimens," said Edward Cox, director of the Office of Antimicrobial Products in the FDA's Center for Drug Evaluation and Research.

"New combination HIV drugs like Stribild help simplify treatment regimens."
The new pill, previously called Quad, is made by Gilead Sciences in California and "should be available to patients by the end of the week," company spokeswoman Erin Rau told AFP.

The company said it tested the pill in two double-blind clinical trials of more than 1,400 patients.
Results showed that Stribild performed as well or better than two other treatment combinations, and brought virus readings down to undetectable levels in around nine of 10 patients after 48 weeks.

"Therapies that address the individual needs of patients are critical to enhancing adherence and increasing the potential for treatment success," Gilead chief John Martin said in a company statement.
But some advocates say the new pill is priced far too high.

"We wanted to see (a price of) no more than the current drug," said Michael Weinstein, president of the AIDS Healthcare Foundation, referring to Gilead's previously approved three-in-one pill, Atripla. But he said the price will be about a third higher than the three-pill combo.

The new drug "is not a significant improvement over existing therapies," Weinstein told AFP, adding the cost will "severely limit access" to the new medication.
Gilead is charging wholesalers $28,500 a year for the drug, but said it will provide discounts to state assistance programs and has created a patient financial-assistance program, Rau said.

This is Gilead's third single-tablet anti-HIV combination therapy, the company noted, adding it is still seeking approval for the newest offering in Australia, Canada and the European Union.
To get the drug to HIV patients in the developing world, where millions lack access to effective treatment options, generic versions are being developed -- with permission and help from Gilead -- by a number of Indian manufacturers and the Medicines Patent Pool, a non-profit that helps facilitate generic drug-making.

The drug combines Truvada -- another Gilead offering approved in 2004, that combines emtricitabine and tenofovir disoproxil fumarate to fight an enzyme that HIV needs to replicate -- with elvitegravir, another enzyme-fighting drug, and cobicistat, which enhances the effects of elvitegravir.

The FDA said further study is required to determine the quad-drug's safety for women and children, how resistance may develop, and whether the drug interacts with other drugs.
Stribild will also be required to carry a label warning patients and health care providers the drug can cause fatal side effects, including severe liver problems, and a build-up of lactic acid in the blood. The FDA said the label is also required for many other HIV-fighting drugs.
But Gilead said that during the studies, "most adverse effects were mild to moderate." The FDA said patients commonly experienced nausea and diarrhea.

The drug also weakened bones and caused or worsened kidney problems -- both of which will be mentioned in a warning on the drug's label.

Truvada was previously approved as a treatment for people infected with HIV to be used in combination with other antiretroviral drugs.
In July, it was also approved for use by healthy at-risk adults to prevent HIV, the first-ever daily pill approved for that purpose.
This year, the FDA also approved the first rapid HIV test that can be bought without a prescription and taken at home.

SOURCE
Re: US Approves Once-a-day HIV Pill by Okijajuju1(m): 4:37pm On Aug 29, 2012
Happy fhucking days are here again... HURRAY!!!

3 Likes

Re: US Approves Once-a-day HIV Pill by EvilBrain1(m): 4:41pm On Aug 29, 2012
Everybody should please note that this is not a cure. Like other HIV drugs, it just keeps the virus at bay and you need to keep taking it for life to prevent you from getting sick.

Keep using those condoms.

1 Like

Re: US Approves Once-a-day HIV Pill by Nobody: 4:41pm On Aug 29, 2012
labazie otu
Re: US Approves Once-a-day HIV Pill by Dranatomy: 4:44pm On Aug 29, 2012
Okija_juju: Happy fhucking days are here again... HURRAY!!!
Continue to Bleep off ur bright future/Gods plans in ur life
Re: US Approves Once-a-day HIV Pill by Nobody: 4:45pm On Aug 29, 2012
Someone even claims he has been totally cured of H.I.V ..

Timothy Ray Brown, 47, an American from Seattle, Washington, rose to fame as the so-called "Berlin patient" after doctors tried a novel technique to use an HIV-resistant donor for a stem cell transplant to treat Brown's leukemia.
Since 2007, he has had two high-risk bone marrow transplants and continues to test negative for HIV, stunning researchers and offering new pathways for research into how gene therapy may lead to a more widely acceptable approach.
"I am living proof that there could be a cure for AIDS," Brown told AFP in an interview. "It's very wonderful, being cured of HIV."
[b][/b]

http://www.gidilinks.com/2012/08/man-who-claim-to-be-cured-of-hiv-aids_29.html
Re: US Approves Once-a-day HIV Pill by Tstark(m): 4:45pm On Aug 29, 2012
Evil Brain: Everybody should please note that this is not a cure. Like other HIV drugs, it just keeps the virus at bay and you need to keep taking it for life to prevent you from getting sick.

Keep using those condoms.

Okija_juju take note o, its not a cure! Before you begin celebrate

grin
Re: US Approves Once-a-day HIV Pill by Martini101(m): 4:48pm On Aug 29, 2012
Ótu agwu ike! Lol
Re: US Approves Once-a-day HIV Pill by nwangeme: 4:48pm On Aug 29, 2012
as if there was a killer disease called HIV...It has been a scam from the beginning.Infact the biggest scam ever known to mankind. The doctors made billions of dollars from the drugs they approved for the treatment (Anti Retroviral Drugs) .Its a simple logic, a pack of high profile doctors conspires to tell the world that HIV exists. These same doctors come out with costly drugs for its treatment. I have never been scared of HIV just scared of other STDs that are really terminal like Herpes.
Re: US Approves Once-a-day HIV Pill by Afam4eva(m): 4:50pm On Aug 29, 2012
The pills are very expensive. I can't afford them right now. I need it fast.
Re: US Approves Once-a-day HIV Pill by ebamma(m): 4:51pm On Aug 29, 2012
Ekaette............,..No bleep me without condom oh,i get hiv/aids
Ebamma...........No worry Ekaette, i get Stribild medicine,make we fire dey go joor
Re: US Approves Once-a-day HIV Pill by mkmyers45(m): 4:55pm On Aug 29, 2012
Brand_new: Someone even claims he has been totally cured of H.I.V ..

Yes, he had complete blood cells transplant and was cured
Re: US Approves Once-a-day HIV Pill by mkmyers45(m): 4:55pm On Aug 29, 2012
afam4eva: The pills are very expensive. I can't afford them right now. I need it fast.

$28,500 dollars no be small thing ooo
Re: US Approves Once-a-day HIV Pill by keneri(m): 5:00pm On Aug 29, 2012
nwa-ngeme:
as if there was a killer disease called HIV...It has been a scam from the beginning.Infact the biggest scam ever known to mankind. The doctors made billions of dollars from the drugs they approved for the treatment (Anti Retroviral Drugs) .Its a simple logic, a pack of high profile doctors conspires to tell the world that HIV exists. These same doctors come out with costly drugs for its treatment. I have never been scared of HIV just scared of other STDs that are really terminal like Herpes.

My dear friend, Herpes is NOT terminal. Its just another kind of oral/sexually transmitted virus. There are two major types, Oral (mouth) and on the reproductive organs. Do your research before running into conclusions. Herpes has no "cure" per sey and can lie dormiant in the system for years until when activated by sickness etc. And pls and Pls HIV/AIDS isn't a conspiracy, it kills both whites and blacks alike. check this out for more info: http://www.cdc.gov/std/herpes/stdfact-herpes.htm

1 Like

Re: US Approves Once-a-day HIV Pill by lanrei(m): 5:00pm On Aug 29, 2012
nwa-ngeme:
as if there was a killer disease called HIV...It has been a scam from the beginning.Infact the biggest scam ever known to mankind. The doctors made billions of dollars from the drugs they approved for the treatment (Anti Retroviral Drugs) .Its a simple logic, a pack of high profile doctors conspires to tell the world that HIV exists. These same doctors come out with costly drugs for its treatment. I have never been scared of HIV just scared of other STDs that are really terminal like Herpes.
i hear u
Re: US Approves Once-a-day HIV Pill by tonyx4x44(m): 5:04pm On Aug 29, 2012
Okija_juju: Happy fhucking days are here again... HURRAY!!!
lol
Re: US Approves Once-a-day HIV Pill by searay(m): 5:11pm On Aug 29, 2012
ebamma: Ekaette............,..No bleep me without condom oh,i get hiv/aids
Ebamma...........No worry Ekaette, i get Stribild medicine,make we fire dey go joor
Must u use Ekaette? Why not use your R.E.T.A.R.D.E.D tribe name?
Re: US Approves Once-a-day HIV Pill by nwangeme: 5:12pm On Aug 29, 2012
keneri:

My dear friend, Herpes is NOT terminal. Its just another kind of oral/sexually transmitted virus. There are two major types, Oral (mouth) and on the reproductive organs. Do your research before running into conclusions. Herpes has no "cure" per sey and can lie dormiant in the system for years until when activated by sickness etc. And pls and Pls HIV/AIDS isn't a conspiracy, it kills both whites and blacks alike. check this out for more info: http://www.cdc.gov/std/herpes/stdfact-herpes.htm
...

"Terminal illness is a medical term popularized in the 20th century to describe a disease that cannot be cured or adequately treated and that is reasonably expected to result in the death of the patient within a period of time" so your telling me the sickness will have to wait for years before activating the herpes right?

yea yea, it kills both white and blacks..i never brought anything about being black or white or green...If you believed so much in medicine and a doctor tells you that you have got some few more years to live what would be your response? Bro, its a simple psychology - KILL THE MIND, KILL THE MAN. i would leave you to your opinion though.
Re: US Approves Once-a-day HIV Pill by Nobody: 5:14pm On Aug 29, 2012
na wa o! wetin consign me! afterall my engine must not break down. undecided undecided undecided
Re: US Approves Once-a-day HIV Pill by 2rutalk1: 5:19pm On Aug 29, 2012
nwa-ngeme:
as if there was a killer disease called HIV...It has been a scam from the beginning.Infact the biggest scam ever known to mankind. The doctors made billions of dollars from the drugs they approved for the treatment (Anti Retroviral Drugs) .Its a simple logic, a pack of high profile doctors conspires to tell the world that HIV exists. These same doctors come out with costly drugs for its treatment. I have never been scared of HIV just scared of other STDs that are really terminal like Herpes.

HIV/AIDS exist but people blow it out of proportion. HIV/AIDS is a SECONDARY MALNUTRITION. What kill people is stigmatization and not AIDS. AIDS can only kill when there is insufficient diet to boost your immune system, which is normal in the life of every living organism, whether AIDS or no AIDS just like other immune deficiency diseases. I am not encouraging casual sex nor other mode of transmission, but the fact remains that AIDS is real but different from the way people think about it.
Re: US Approves Once-a-day HIV Pill by dino2006(m): 5:22pm On Aug 29, 2012
This new innovation would go a long way in improving patient's compliance to ARVs, a critical issue in the chemotherapy of AIDS.
However, this is no much different from the existing combo regimens, HAART et al, currently used.
I also implore the patent manufacturer to grant permissions to local manufacturers in developing countries, willing to produce d generic drug, which would be far cheaper $ accessible than d patent drug.
Of a truth, drug production is very expensive, and only about 2 out of every 10 marketed drugs, return their R$D investments.
On a final note, Pervention, they say is better than Cure ( Management in this case). If you cannot abstain, use a c.ondom.

Cheers.
Re: US Approves Once-a-day HIV Pill by Nobody: 5:41pm On Aug 29, 2012
Malaria is more deadly than HIV.
Re: US Approves Once-a-day HIV Pill by curtain: 5:51pm On Aug 29, 2012
Killing is killing the only difference is how fast. For now in nigeria the fastest killer is boko, making many h.i.v victims outlived dos witout it. Any cure for boko yet?

4 Likes

Re: US Approves Once-a-day HIV Pill by dreu2fine(m): 5:54pm On Aug 29, 2012
Did u guys note dat d side effect fit kill person self is worst

1 Like

Re: US Approves Once-a-day HIV Pill by sureboykris(m): 5:55pm On Aug 29, 2012
nwa-ngeme:
as if there was a killer disease called HIV...It has been a scam from the beginning.Infact the biggest scam ever known to mankind. The doctors made billions of dollars from the drugs they approved for the treatment (Anti Retroviral Drugs) .Its a simple logic, a pack of high profile doctors conspires to tell the world that HIV exists. These same doctors come out with costly drugs for its treatment. I have never been scared of HIV just scared of other STDs that are really terminal like Herpes.
Ūя̲̅ ignorance might lead U̶̲̥̅̊ to an untimely death. HIV is real. I've watched it kill lots n lots of peeps
Re: US Approves Once-a-day HIV Pill by sureboykris(m): 5:57pm On Aug 29, 2012
nwa-ngeme:
as if there was a killer disease called HIV...It has been a scam from the beginning.Infact the biggest scam ever known to mankind. The doctors made billions of dollars from the drugs they approved for the treatment (Anti Retroviral Drugs) .Its a simple logic, a pack of high profile doctors conspires to tell the world that HIV exists. These same doctors come out with costly drugs for its treatment. I have never been scared of HIV just scared of other STDs that are really terminal like Herpes.
pls don't let Ūя̲̅ attitude lead U̶̲̥̅̊ to an early grave. I've watched HIV kill lots of peeps
Re: US Approves Once-a-day HIV Pill by Tolaaaaannni(f): 6:03pm On Aug 29, 2012
nwa-ngeme:
as if there was a killer disease called HIV...It has been a scam from the beginning.Infact the biggest scam ever known to mankind. The doctors made billions of dollars from the drugs they approved for the treatment (Anti Retroviral Drugs) .Its a simple logic, a pack of high profile doctors conspires to tell the world that HIV exists. These same doctors come out with costly drugs for its treatment. I have never been scared of HIV just scared of other STDs that are really terminal like Herpes.

Keep living in denial. Have fun dying of A.I.D.S smiley
Re: US Approves Once-a-day HIV Pill by nwangeme: 6:03pm On Aug 29, 2012
sureboykris: pls don't let Ūя̲̅ attitude lead U̶̲̥̅̊ to an early grave. I've watched HIV kill lots of peeps

i was going to call you a R E T A R D but i just remembered that my cousin's neigbour's little puppy died today so am gonna let you pass.

1 Like

Re: US Approves Once-a-day HIV Pill by SimplySEA(m): 6:05pm On Aug 29, 2012
berem!:
na wa o! wetin consign me! afterall my engine must not break down. undecided undecided undecided
Na wa o....! Na a lady de make dis kine statement o! What's happened to decency...?

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