₦airaland Forum

Welcome, Guest: Join Nairaland / LOGIN! / Trending / Recent / New
Stats: 2,136,211 members, 4,637,085 topics. Date: Thursday, 13 December 2018 at 07:21 AM

Ebola Vaccine Works, Offering 100% Protection In African Trial - Health - Nairaland

Nairaland Forum / Nairaland / General / Health / Ebola Vaccine Works, Offering 100% Protection In African Trial (12638 Views)

New Ebola Vaccine Gives 100% Protection Against The Disease — WHO Reports / First New HIV Vaccine Trial Begins In Africa / Nasiru Shua’ibu Develops Malaria Vaccine (2) (3) (4)

(1) (2) (3) (4) (Reply) (Go Down)

Ebola Vaccine Works, Offering 100% Protection In African Trial by Nobody: 3:12pm On Aug 02, 2015
A man in the Guinean capital Conakry receiving the experimental Ebola vaccine in April.

A highly unusual clinical trial in Guinea has shown for the first time that an Ebola vaccine protects people from the deadly virus. The study, published online today by The Lancet, shows that the injection offered contacts of Ebola cases 100% protection starting 10 days after they received a single shot of the vaccine, which is produced by Merck. Scientists say the vaccine could help to finally bring an end to the epidemic in West Africa, now more than 18 months old.

"This will go down in history as one of those hallmark public health efforts," says Michael Osterholm, the director of the Center for Infectious Disease Research and Policy in Twin Cities, Minnesota, who wasn't involved in the study. "We will teach about this in public health schools."

"It's a wonderful result and a fantastic illustration of how vaccines can be developed very quickly and can be used in an outbreak situation to control the disease," says Adrian Hill, a vaccine researcher at the University of Oxford in the United Kingdom, also not involved in the work.

The vaccine, first developed by researchers at the Public Health Agency of Canada, consists of the Vesicular Stomatitis Virus (VSV), which causes disease in livestock but not people, with the Ebola surface protein stitched into it. It is one of two vaccines currently being tested in the Ebola-stricken countries; the other one is produced by GlaxoSmithKline (GSK). The study of the Merck vaccine was led by Ana Maria Henao-Restrepo of the World Health Organization (WHO) in Geneva, together with colleagues at the Norwegian Institute of Public Health in Oslo, the Guinean Ministry of Health, and others.

The decision to start the trial was taken in October, but it didn't get off the ground until March. By then, Ebola cases had already begun to plummet, and they were scattered across a large area in Guinea. To show efficacy in a standard randomized controlled trial, the researchers would have had to enroll far more people than was feasible.

Instead, they opted for a design called ring vaccination, in which only contacts of new Ebola patients, as well as the contacts' contacts, were vaccinated. The rings, or clusters, were randomized; in 48 of them, vaccination occurred as soon as possible after the detection of the Ebola case in their community. In the 42 other clusters, the vaccination teams came to give the shots three weeks later. The researchers then counted the number of new Ebola cases in each ring; because they weren't sure how long it takes for the vaccine's protection to kick in, they only included cases that occurred at least 10 days after vaccination in their primary analysis of the data. There were zero such cases among the 2014 people who were vaccinated right away, and 16 among the 2380 who got the shot 3 weeks later. That translates to 100% vaccine efficacy, at least in this study, the researchers write.

The idea of a ring vaccination design, never before used in a formal vaccine study, "was absolutely very creative," says Osterholm, and it allowed the team to follow the epidemic wherever it went. "Had this been a standard, straightforward randomized controlled trial, we would never had this answer.”

"It surprised me how quickly you can intervene with a vaccination and have an effect," says Jeremy Farrar, the head of the Wellcome Trust research charity, which co-funded the study. "It’s possible to do that sort of complex work in very, very complex environments—ethically, socially, culturally and scientifically. You can do it. That is a revelation for many people."


Source: http://news.sciencemag.org/health/2015/07/ebola-vaccine-works-offering-100-protection-african-trial

8 Likes 3 Shares

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by chiboyo(m): 3:14pm On Aug 02, 2015
This is good news

3 Likes

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by davuvid(m): 3:15pm On Aug 02, 2015
This kinda news is what I wanna keep hearing..

6 Likes

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by stchinedu: 3:21pm On Aug 02, 2015
Loving this.

2 Likes 1 Share

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by shadelek(m): 9:35am On Aug 03, 2015
This deadly disease now has remedy, kudos to the vaccine developer(s), more grease to your elbow(s).

9 Likes

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by ogunwalea(m): 9:35am On Aug 03, 2015
Isokay
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by justi4jesu(f): 9:36am On Aug 03, 2015
Good News.
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by Tonniey(m): 9:36am On Aug 03, 2015
I am waiting for dat day when solutions to health challenges perculia to africa will b solved my african scientists

26 Likes 3 Shares

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by SaiBuharii: 9:36am On Aug 03, 2015
So we can start contacting Ebola?

7 Likes

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by bunmioguns(m): 9:36am On Aug 03, 2015
cool
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by horllami07(f): 9:36am On Aug 03, 2015
Good
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by magabounce(m): 9:36am On Aug 03, 2015
Wokey o
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by DankemzI(m): 9:36am On Aug 03, 2015
"It's a wonderful result and a fantastic illustration of how vaccines can be developed very quickly and can be used in an outbreak situation to control the disease," says Adrian Hill, a vaccine researcher at the University of Oxford in the United Kingdom, also not involved in the work.


Them albino have hijacked our glory
Made in black, made by Blacks, and made for blacks
Where to go Africagrin
Time to solve our problems
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by Georgekyrian(m): 9:37am On Aug 03, 2015
Godwin
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by Adonispco: 9:37am On Aug 03, 2015
Awesome
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by psychologist(m): 9:37am On Aug 03, 2015
The only thing nija doctors are good at is strike strike and strike again tongue

10 Likes

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by OluwaDavidow1(m): 9:37am On Aug 03, 2015
Hmm
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by mrlaw93(m): 9:37am On Aug 03, 2015
Good news.. What is Ebola?
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by Bawsse(m): 9:38am On Aug 03, 2015
Gg
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by Swagavillage(m): 9:38am On Aug 03, 2015
good
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by omenpetrol: 9:38am On Aug 03, 2015
Conspiracy!!!!.....Drop a virus........Act like a Savior........Create a Vaccine.......Make money........the cycle goes on.

11 Likes 2 Shares

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by islandmoon: 9:39am On Aug 03, 2015
really?
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by magabounce(m): 9:39am On Aug 03, 2015
changed ma mind
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by fornaija(m): 9:39am On Aug 03, 2015
Finally! Here we go!
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by naijathings(m): 9:39am On Aug 03, 2015
thank God.
I heard there is now vaccine for malaria too. very good.
But the thing is that somehow, another DEADLY disease always manages to find its way into earth to disturb humans and cause fear and death.
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by dayo23: 9:40am On Aug 03, 2015
Good news
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by Remilekun101: 9:40am On Aug 03, 2015
sad
Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by Remilekun101: 9:40am On Aug 03, 2015
that poster above me is booking space

1 Like

Re: Ebola Vaccine Works, Offering 100% Protection In African Trial by Dharniel(m): 9:40am On Aug 03, 2015
progress...

(1) (2) (3) (4) (Reply)

Czech Man Becomes The First Person In The World To Live With No Heart Or Pulse / US Approves Once-a-day HIV Pill / Women: Know More About Pelvic Inflammatory Disease (PID)

(Go Up)

Sections: politics (1) business autos (1) jobs (1) career education (1) romance computers phones travel sports fashion health
religion celebs tv-movies music-radio literature webmasters programming techmarket

Links: (0) (1) (2) (3) (4) (5) (6) (7) (8) (9)

Nairaland - Copyright © 2005 - 2018 Oluwaseun Osewa. All rights reserved. See How To Advertise. 82
Disclaimer: Every Nairaland member is solely responsible for anything that he/she posts or uploads on Nairaland.