[b][/b]What is hepatitis?
A: Hepatitis is an inflammation of the liver. The condition can be self-limiting or can progress to fibrosis (scarring), cirrhosis or liver cancer. Hepatitis viruses are the most common cause of hepatitis in the world but other infections, toxic substances (e.g. alcohol, certain drugs), and autoimmune diseases can also cause hepatitis.
There are 5 main hepatitis viruses, referred to as types A, B, C, D and E. These 5 types are of greatest concern because of the burden of illness and death they cause and the potential for outbreaks and epidemic spread. In particular, types B and C lead to chronic disease in hundreds of millions of people and, together, are the most common cause of liver cirrhosis and cancer.
Hepatitis A and E are typically caused by ingestion of contaminated food or water. Hepatitis B, C and D usually occur as a result of parenteral contact with infected body fluids. Common modes of transmission for these viruses include receipt of contaminated blood or blood products, invasive medical procedures using contaminated equipment and for hepatitis B transmission from mother to baby at birth, from family member to child, and also by sexual contact.
Acute infection may occur with limited or no symptoms, or may include symptoms such as jaundice (yellowing of the skin and eyes), dark urine, extreme fatigue, nausea, vomiting and abdominal pain.
Q: What are the different hepatitis viruses?
A: Scientists have identified 5 unique hepatitis viruses, identified by the letters A, B, C, D, and E. While all cause liver disease, they vary in important ways.
Hepatitis A virus (HAV) is present in the faeces of infected persons and is most often transmitted through consumption of contaminated water or food. Certain sex practices can also spread HAV. Infections are in many cases mild, with most people making a full recovery and remaining immune from further HAV infections. However, HAV infections can also be severe and life threatening. Most people in areas of the world with poor sanitation have been infected with this virus. Safe and effective vaccines are available to prevent HAV.
Hepatitis B virus (HBV) is transmitted through exposure to infective blood, semen, and other body fluids. HBV can be transmitted from infected mothers to infants at the time of birth or from family member to infant in early childhood. Transmission may also occur through transfusions of HBV-contaminated blood and blood products, contaminated injections during medical procedures, and through injection drug use. HBV also poses a risk to healthcare workers who sustain accidental needle stick injuries while caring for infected-HBV patients. Safe and effective vaccines are available to prevent HBV.
Hepatitis C virus (HCV) is mostly transmitted through exposure to infective blood. This may happen through transfusions of HCV-contaminated blood and blood products, contaminated injections during medical procedures, and through injection drug use. Sexual transmission is also possible, but is much less common. There is no vaccine for HCV.
Hepatitis D virus (HDV) infections occur only in those who are infected with HBV. The dual infection of HDV and HBV can result in a more serious disease and worse outcome. Hepatitis B vaccines provide protection from HDV infection.
Hepatitis E virus (HEV) is mostly transmitted through consumption of contaminated water or food. HEV is a common cause of hepatitis outbreaks in developing parts of the world and is increasingly recognized as an important cause of disease in developed countries. Safe and effective vaccines to prevent HEV infection have been developed but are not widely available.

Signs and symptoms
Many people with hepatitis experience either mild symptoms or none at all. Remember that an infected person's feces are always infectious to other people. When symptoms appear, they usually do so about 15 to 180 days after the person has become infected.




The acute phase of hepatitis - symptoms

The initial phase of hepatitis is called the acute phase. The symptoms are like a mild flu, and may include:
Diarrhea
Fatigue
Loss of appetite
Mild fever
Muscle or joint aches
Nausea
Slight abdominal pain
Vomiting
Weight loss.
The acute phase is not usually dangerous, unless it develops into the fulminant or rapidly progressing form, which can lead to death.
As the patient gets worse, these symptoms may follow:
Circulation problems (only toxic/drug-induced hepatitis)
Dark urine
Dizziness (only toxic/drug-induced hepatitis)
Drowsiness (only toxic/drug-induced hepatitis)
Enlarged spleen (only alcoholic hepatitis)
Headache (only toxic/drug-induced hepatitis)
Hives
Itchy skin
Light colored feces, the feces may contain pus
Yellow skin, whites of eyes, tongue (jaundice).
Patient outcomes after the acute phase depend on various factors, especially the type of hepatitis.

Hepatitis A transmitted by food
The hepatitis A virus is one of the most frequent causes of foodborne infection. Epidemics related to contaminated food or water can erupt explosively, such as the epidemic in Shanghai in 1988 that affected about 300 000 people. Hepatitis A viruses persist in the environment and can resist food-production processes routinely used to inactivate and/or control bacterial pathogens.
The disease can lead to significant economic and social consequences in communities. It can take weeks or months for people recovering from the illness to return to work, school or daily life. The impact on food establishments identified with the virus, and local productivity in general, can be substantial.




Preventing hepatitis
How to prevent hepatitis A
Wash your hands with soap after going to the toilet
Only consume food that has just been cooked
Only drink commercially bottled water, or boiled water if you're unsure of local sanitation
Only eat fruits that you can peel if you are somewhere where sanitation is unreliable
Only eat raw vegetables if you are sure they have been cleaned/disinfected thoroughly
Get a vaccine for hepatitis A if you travel to places where hepatitis may be endemic.
How to prevent hepatitis B
Tell the partner if you are a carrier or try to find out whether he/she is a carrier
Practice safe sex
Only use clean syringes that have not been used by anyone else
Do not share toothbrushes, razors, or manicure instruments
Have a hepatitis B series of shots if you are at risk
Only allow well sterilized skin perforating equipment (tattoo, acupuncture, etc.).
How to prevent hepatitis C
If you are infected do not let others share your toothbrush, razor, manicure equipment
If you are infected cover open wounds
Do not share needles, toothbrushes, or manicure equipment
If your skin is to be pierced, make sure equipment is well sterilized (tattoo, etc.)
Go easy on the alcohol
Do not share drug equipment.
How to prevent hepatitis D
Use the same guidelines as for hepatitis B. Only a person who is infected with hepatitis B can become infected with hepatitis D.
How to prevent hepatitis E
Do the same as you would to protect yourself from hepatitis A infection.
How to prevent alcoholic hepatitis
Go easy on the alcohol, or abstain from consuming alcohol.
How to prevent toxic/drug induced hepatitis
Make sure you know about the lethal contents of all chemicals
Make sure the spray is not pointing at you
Make sure you wear protective gear if you have to.
How is it treated?
Antiviral medications. Several antiviral medications — including lamivudine (Epivir), adefovir (Hepsera), telbivudine (Tyzeka) and entecavir (Baraclude) — can help fight the virus and slow its ability to damage your liver. ...
Interferon alfa-2b (Intron A). ...
Liver transplant.

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