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What is low libido?

Low libido describes a decreased interest in sexual activity.

It’s common to lose interest in sex from time to time, and libido levels vary through life. It’s also normal for your interest not to match your partner’s at times.

However, low libido for a long period of time may cause concern for some people. It can sometimes be an indicator of an underlying health condition.

Here are a few potential causes of low libido in men.

Low testosterone.

Testosterone is an important male hormone. In men, it’s mostly produced in the testicles.

Testosterone is responsible for building muscles and bone mass, and for stimulating sperm production. Your testosterone levels also factor into your sex drive.

Normal testosterone levels will vary. However, adult men are considered to have low testosterone, or low T, when their levels fall below 300 nanograms per deciliter (ng/dL), according to guidelines from the American Urological Association (AUA).


When your testosterone levels decrease, your desire for sex also decreases.

Decreasing testosterone is a normal part of aging. However, a drastic drop in testosterone can lead to decreased libido.

Talk to your doctor if you think this might be an issue for you. You may be able to take supplements or gels to increase your testosterone levels.

Depression.

Depression changes all parts of a person’s life. People with depression experience a reduced or complete lack of interest in activities they once found pleasurable, including sex.
Also all this can cause it.
Alcohol, Drug use.



LOW SPERM COUNT.

Low sperm count means that the fluid (semen) you ejaculate during an orgasm contains fewer sperm than normal.

A low sperm count is also called oligospermia (ol-ih-go-SPUR-me-uh). A complete absence of sperm is called azoospermia. Your sperm count is considered lower than normal if you have fewer than 15 million sperm per milliliter of semen.

Having a low sperm count decreases the odds that one of your sperm will fertilize your partner's egg, resulting in pregnancy. Nonetheless, many men who have a low sperm count are still able to father a child.

Symptoms
The main sign of low sperm count is the inability to conceive a child. There might be no other obvious signs or symptoms. In some men, an underlying problem such as an inherited chromosomal abnormality, a hormonal imbalance, dilated testicular veins or a condition that blocks the passage of sperm may cause signs and symptoms.

Low sperm count symptoms might include:

Problems with sexual function — for example, low sex drive or difficulty maintaining an erection (erectile dysfunction)
Pain, swelling or a lump in the testicle area
Decreased facial or body hair or other signs of a chromosome or hormone abnormality.

When to see a doctor.

See a doctor if you have been unable to conceive a child after a year of regular, unprotected intercourse or sooner if you have any of the following:

Erection or ejaculation problems, low sex drive, or other problems with sexual function
Pain, discomfort, a lump or swelling in the testicle area
A history of testicle, prostate or sexual problems
A groin, testicle, penis or scrotum surgery.

Causes.

The production of sperm is a complex process and requires normal functioning of the testicles (testes) as well as the hypothalamus and pituitary glands — organs in your brain that produce hormones that trigger sperm production. Once sperm are produced in the testicles, delicate tubes transport them until they mix with semen and are ejaculated out of the penis. Problems with any of these systems can affect sperm production.

Also, there can be problems of abnormal sperm shape (morphology), movement (motility) or function.

However, often the cause of low sperm count isn't identified.

Medical causes.

Low sperm count can be caused by a number of health issues and medical treatments. Some of these include:

Varicocele.

A varicocele (VAR-ih-koe-seel) is a swelling of the veins that drain the testicle. It's the most common reversible cause of male infertility. Although the exact reason that varicoceles cause infertility is unknown, it might be related to abnormal testicular temperature regulation. Varicoceles result in reduced quality of the sperm.

Infection.

Some infections can interfere with sperm production or sperm health or can cause scarring that blocks the passage of sperm. These include inflammation of the epididymis (epididymitis) or testicles (orchitis) and some sexually transmitted infections, including gonorrhea or HIV. Although some infections can result in permanent testicular damage, most often sperm can still be retrieved.
Ejaculation problems. Retrograde ejaculation occurs when semen enters the bladder during orgasm instead of emerging out of the tip of the penis. Various health conditions can cause retrograde ejaculation or lack of ejaculation, including diabetes, spinal injuries, and surgery of the bladder, prostate or urethra.

Certain medications also might result in ejaculatory problems, such as blood pressure medications known as alpha blockers. Some ejaculatory problems can be reversed, while others are permanent. In most cases of permanent ejaculation problems, sperm can still be retrieved directly from the testicles.

Antibodies that attack sperm. Anti-sperm antibodies are immune system cells that mistakenly identify sperm as harmful invaders and attempt to destroy them.
Tumors. Cancers and nonmalignant tumors can affect the male reproductive organs directly, through the glands that release hormones related to reproduction, such as the pituitary gland, or through unknown causes. Surgery, radiation or chemotherapy to treat tumors also can affect male fertility.
Undescended testicles. During fetal development one or both testicles sometimes fail to descend from the abdomen into the sac that normally contains the testicles (scrotum). Decreased fertility is more likely in men with this condition.
Hormone imbalances. The hypothalamus, pituitary and testicles produce hormones that are necessary to create sperm. Alterations in these hormones, as well as from other systems such as the thyroid and adrenal gland, may impair sperm production.
Defects of tubules that transport sperm. Many different tubes carry sperm. They can be blocked due to various causes, including inadvertent injury from surgery, prior infections, trauma or abnormal development, such as with cystic fibrosis or similar inherited conditions.

Blockage can occur at any level, including within the testicle, in the tubes that drain the testicle, in the epididymis, in the vas deferens, near the ejaculatory ducts or in the urethra.

Chromosome defects. Inherited disorders such as Klinefelter's syndrome — in which a male is born with two X chromosomes and one Y chromosome instead of one X and one Y — cause abnormal development of the male reproductive organs. Other genetic syndromes associated with infertility include cystic fibrosis, Kallmann's syndrome and Kartagener's syndrome.
Celiac disease. A digestive disorder caused by sensitivity to gluten, celiac disease can cause male infertility. Fertility may improve after adopting a gluten-free diet.
Certain medications. Testosterone replacement therapy, long-term anabolic steroid use, cancer medications (chemotherapy), certain antifungal and antibiotic medications, some ulcer medications, and other medications can impair sperm production and decrease male fertility.
Prior surgeries. Certain surgeries might prevent you from having sperm in your ejaculate, including vasectomy, inguinal hernia repairs, scrotal or testicular surgeries, prostate surgeries, and large abdominal surgeries performed for testicular and rectal cancers, among others. In most cases, surgery can be performed to either reverse these blockages or to retrieve sperm directly from the epididymis and testicles.
Environmental causes
Sperm production or function can be affected by overexposure to certain environmental elements, including:

Industrial chemicals. Extended exposure to benzenes, toluene, xylene, herbicides, pesticides, organic solvents, painting materials and lead might contribute to low sperm counts.
Heavy metal exposure. Exposure to lead or other heavy metals also can cause infertility.
Radiation or X-rays. Exposure to radiation can reduce sperm production. It can take several years for sperm production to return to normal. With high doses of radiation, sperm production can be permanently reduced.
Overheating the testicles. Elevated temperatures impair sperm production and function.Although studies are limited and are inconclusive, frequent use of saunas or hot tubs might temporarily impair sperm count.

Sitting for long periods, wearing tight clothing or working on a laptop computer for long stretches of time also might increase the temperature in your scrotum and slightly reduce sperm production.

Health, lifestyle and other causes
Other causes of low sperm count include:

Drug use.

Anabolic steroids taken to stimulate muscle strength and growth can cause the testicles to shrink and sperm production to decrease. Use of cocaine or marijuana might reduce the number and quality of your sperm as well.

Alcohol use.

Drinking alcohol can lower testosterone levels and cause decreased sperm production.
Occupation. Certain occupations might be linked with a risk of infertility, including welding or those associated with prolonged sitting, such as truck driving. However, the data to support these associations is inconsistent.
Tobacco smoking. Men who smoke might have a lower sperm count than do those who don't smoke.
Emotional stress. Severe or prolonged emotional stress, including stress about fertility, might interfere with hormones needed to produce sperm.

Depression.

Being depressed may negatively affect sperm concentration.
Weight. Obesity can impair fertility in several ways, including directly impacting sperm and by causing hormone changes that reduce male fertility.
Sperm testing issues. Lower than normal sperm counts can result from testing a sperm sample that was taken too soon after your last ejaculation; was taken too soon after an illness or stressful event; or didn't contain all of the semen you ejaculated because some was spilled during collection. For this reason, results are generally based on several samples taken over a period of time.

Risk factors.

A number of risk factors are linked to low sperm count and other problems that can cause low sperm count. They include:

Smoking tobacco
Drinking alcohol
Using certain illicit drugs
Being overweight
Being severely depressed or stressed
Having certain past or present infections
Being exposed to toxins
Overheating the testicles
Having experienced trauma to the testicles
Being born with a fertility disorder or having a blood relative, such as your brother or father, with a fertility disorder
Having certain medical conditions, including tumors and chronic illnesses
Undergoing cancer treatments, such as radiation
Taking certain medications
Having a prior vasectomy or major abdominal or pelvic surgery
Having a history of undescended testicles
Complications
Infertility caused by low sperm count can be stressful for both you and your partner. Complications can include:

Surgery or other treatments for an underlying cause of low sperm count
Expensive and involved assisted reproductive techniques, such as in vitro fertilization (IVF)
Stress related to the inability to have a child.
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Appendicitis.
Is an inflammation of the appendix, a finger-shaped pouch that projects from your colon on the lower right side of your abdomen. The appendix doesn't seem to have a specific purpose.

Appendicitis causes pain in your lower right abdomen. However, in most people, pain begins around the navel and then moves. As inflammation worsens, appendicitis pain typically increases and eventually becomes severe.

Although anyone can develop appendicitis, most often it occurs in people between the ages of 10 and 30. Standard treatment is surgical removal of the appendix.

Symptoms.

Signs and symptoms of appendicitis may include:

Sudden pain that begins on the right side of the lower abdomen
Sudden pain that begins around your navel and often shifts to your lower right abdomen
Pain that worsens if you cough, walk or make other jarring movements
Nausea and vomiting
Loss of appetite
Low-grade fever that may worsen as the illness progresses
Constipation or diarrhea
Abdominal bloating
The site of your pain may vary, depending on your age and the position of your appendix. When you're pregnant, the pain may seem to come from your upper abdomen because your appendix is higher during pregnancy.

Causes.

A blockage in the lining of the appendix that results in infection is the likely cause of appendicitis. The bacteria multiply rapidly, causing the appendix to become inflamed, swollen and filled with pus. If not treated promptly, the appendix can rupture.

Complications.

Appendicitis can cause serious complications, such as:

A ruptured appendix. A rupture spreads infection throughout your abdomen (peritonitis). Possibly life-threatening, this condition requires immediate surgery to remove the appendix and clean your abdominal cavity.
A pocket of pus that forms in the abdomen. If your appendix bursts, you may develop a pocket of infection (abscess). In most cases, a surgeon drains the abscess by placing a tube through your abdominal wall into the abscess. The tube is left in place for two weeks, and you're given antibiotics to clear the infection.

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A stroke occurs when the blood supply to part of your brain is interrupted or reduced, depriving brain tissue of oxygen and nutrients. Within minutes, brain cells begin to die.

A stroke is a medical emergency. Prompt treatment is crucial. Early action can minimize brain damage and potential complications.

The good news is that strokes can be treated and prevented, and many fewer Americans die of stroke now than in the past.
Symptoms
Watch for these signs and symptoms if you think you or someone else may be having a stroke. Pay attention to when the signs and symptoms begin. The length of time they have been present can affect your treatment options:

Trouble with speaking and understanding. You may experience confusion. You may slur your words or have difficulty understanding speech.
Paralysis or numbness of the face, arm or leg. You may develop sudden numbness, weakness or paralysis in your face, arm or leg. This often happens just on one side of your body. Try to raise both your arms over your head at the same time. If one arm begins to fall, you may be having a stroke. Also, one side of your mouth may droop when you try to smile.
Trouble with seeing in one or both eyes. You may suddenly have blurred or blackened vision in one or both eyes, or you may see double.
Headache. A sudden, severe headache, which may be accompanied by vomiting, dizziness or altered consciousness, may indicate you're having a stroke.
Trouble with walking. You may stumble or experience sudden dizziness, loss of balance or loss of coordination.
When to see a doctor
Seek immediate medical attention if you notice any signs or symptoms of a stroke, even if they seem to fluctuate or disappear. Think "FAST" and do the following:

FACE.
Ask the person to smile. Does one side of the face droop?
ARMS.
Ask the person to raise both arms. Does one arm drift downward? Or is one arm unable to rise up?
SPEECH.
Ask the person to repeat a simple phrase. Is his or her speech slurred or strange?
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A stroke occurs when the blood supply to part of your brain is interrupted or reduced, depriving brain tissue of oxygen and nutrients. Within minutes, brain cells begin to die.

A stroke is a medical emergency. Prompt treatment is crucial. Early action can minimize brain damage and potential complications.

The good news is that strokes can be treated and prevented, and many fewer Americans die of stroke now than in the past.

Symptoms.

Watch for these signs and symptoms if you think you or someone else may be having a stroke. Pay attention to when the signs and symptoms begin. The length of time they have been present can affect your treatment options:

Trouble with speaking and understanding. You may experience confusion. You may slur your words or have difficulty understanding speech.
Paralysis or numbness of the face, arm or leg. You may develop sudden numbness, weakness or paralysis in your face, arm or leg. This often happens just on one side of your body. Try to raise both your arms over your head at the same time. If one arm begins to fall, you may be having a stroke. Also, one side of your mouth may droop when you try to smile.
Trouble with seeing in one or both eyes. You may suddenly have blurred or blackened vision in one or both eyes, or you may see double.
Headache. A sudden, severe headache, which may be accompanied by vomiting, dizziness or altered consciousness, may indicate you're having a stroke.
Trouble with walking. You may stumble or experience sudden dizziness, loss of balance or loss of coordination.

Causes.

A stroke may be caused by a blocked artery (ischemic stroke) or the leaking or bursting of a blood vessel (hemorrhagic stroke). Some people may experience only a temporary disruption of blood flow to the brain (transient ischemic attack, or TIA) that doesn't cause permanent damage.
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SCANTY PERIOD / SPOTTING .

Scanty menstrual periods are periods in which the duration of blood flow is less than two days or the amount of blood flow is less than 80ml.

Most women though, use the term to mainly mean a decreased blood flow, even if the duration of the periods are more than 2 days. So here, the term ‘scanty periods’ has been used to describe both periods with a decreased blood flow, as well as periods with a duration of less than two days.

The medical term for less blood flow during periods is ‘hypomenorrhoea’. And when periods occur at more than a gap of 35 days, it is called ‘oligomenorrhea’. A gap of less than 35 days between two menstrual periods is considered normal.
Causes of Scanty Blood Flow During the Period

Constitutional Causes.
In some women it may be normal to have less bleeding during the menstrual periods. Less blood flow may be genetic and, if enquiries are made, it may be found that the woman’s mother and/or sisters also have decreased blood flow during their periods. pregnancy can normally occur with with this type of decreased flow during the periods. The incidence of infertility is the same as in women with a normal blood flow. -

Extremes of Reproductive Lives.
Scanty menses or periods can occur normally at the extremes of reproductive life – that is, just after puberty and just before menopause. This is because ovulation is irregular at this time, and the endometrial lining fails to develop normally.
Anovulation:

But hormonal problems at other times can also cause scanty blood flow. Anovulation due to a low thyroid hormone level, high prolactin level, high insulin level, high androgen level and problems with other hormones can also cause scanty periods.

Uterine Cause

Blood flow during a period depends on the normal growth of the endometrium (internal uterine lining). If there is a scar inside the uterus the surface area of the endometrium may be smaller than normal. Scarring can occur after operations on the uterus like a myomectomy (removal of fibroids), after radiation treatment or in conditions like Asherman’s syndrome. This may cause less blood flow during the periods.

Emotional Causes

Sometimes psychological factors can come into play. Emotions and stress can act on the centers in the brain that stimulate the ovaries during the ovarian cycle. If these centers in the brain are suppressed due to stress, they fail to stimulate the ovaries to ovulate, leading to less or no production of estrogens and hence scanty menses or periods.
Other Causes

Other causes that can cause scanty or decreased blood flow during the periods are excessive exercise, crash dieting, change in the environment (such as by changing a job), stress due to exams, excessive excitement due to an upcoming event can all cause scanty or less blood flow during the periods.

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Uterine fibroids are noncancerous growths of the uterus that often appear during childbearing years. Also called leiomyomas (lie-o-my-O-muhs) or myomas, uterine fibroids aren't associated with an increased risk of uterine cancer and almost never develop into cancer.

Fibroids range in size from seedlings, undetectable by the human eye, to bulky masses that can distort and enlarge the uterus. You can have a single fibroid or multiple ones. In extreme cases, multiple fibroids can expand the uterus so much that it reaches the rib cage.

Many women have uterine fibroids sometime during their lives. But most women don't know they have uterine fibroids because they often cause no symptoms. Your doctor may discover fibroids incidentally during a pelvic exam or prenatal ultrasound.

Symptoms
Many women who have fibroids don't have any symptoms. In those that do, symptoms can be influenced by the location, size and number of fibroids. In women who have symptoms, the most common symptoms of uterine fibroids include:

Heavy menstrual bleeding
Menstrual periods lasting more than a week
Pelvic pressure or pain
Frequent urination
Difficulty emptying the bladder
Constipation
Backache or leg pains.
Uterine fibroids are noncancerous growths of the uterus that often appear during childbearing years. Also called leiomyomas (lie-o-my-O-muhs) or myomas, uterine fibroids aren't associated with an increased risk of uterine cancer and almost never develop into cancer.

Fibroids range in size from seedlings, undetectable by the human eye, to bulky masses that can distort and enlarge the uterus. You can have a single fibroid or multiple ones. In extreme cases, multiple fibroids can expand the uterus so much that it reaches the rib cage.

Many women have uterine fibroids sometime during their lives. But most women don't know they have uterine fibroids because they often cause no symptoms. Your doctor may discover fibroids incidentally during a pelvic exam or prenatal ultrasound.

Symptoms
Many women who have fibroids don't have any symptoms. In those that do, symptoms can be influenced by the location, size and number of fibroids. In women who have symptoms, the most common symptoms of uterine fibroids include:

Heavy menstrual bleeding
Menstrual periods lasting more than a week
Pelvic pressure or pain

Frequent urination
Difficulty emptying the bladder
Constipation
Backache or leg pains.
Causes
Doctors don't know the cause of uterine fibroids, but research and clinical experience point to these factors:

Genetic changes. Many fibroids contain changes in genes that differ from those in normal uterine muscle cells.
Hormones. Estrogen and progesterone, two hormones that stimulate development of the uterine lining during each menstrual cycle in preparation for pregnancy, appear to promote the growth of fibroids. Fibroids contain more estrogen and progesterone receptors than normal uterine muscle cells do. Fibroids tend to shrink after menopause due to a decrease in hormone production.
Other growth factors. Substances that help the body maintain tissues, such as insulin-like growth factor, may affect fibroid growth.
Doctors believe that uterine fibroids develop from a stem cell in the smooth muscular tissue of the uterus (myometrium). A single cell divides repeatedly, eventually creating a firm, rubbery mass distinct from nearby tissue.

The growth patterns of uterine fibroids vary — they may grow slowly or rapidly, or they may remain the same size. Some fibroids go through growth spurts, and some may shrink on their own. Many fibroids that have been present during pregnancy shrink or disappear after pregnancy, as the uterus goes back to a normal size.
Risk factors
There are few known risk factors for uterine fibroids, other than being a woman of reproductive age. Other factors that can have an impact on fibroid development include:

Heredity. If your mother or sister had fibroids, you're at increased risk of developing them.
Race. Black women are more likely to have fibroids than women of other racial groups. In addition, black women have fibroids at younger ages, and they're also likely to have more or larger fibroids.
Environmental factors. Onset of menstruation at an early age; use of birth control; obesity; a vitamin D deficiency; having a diet higher in red meat and lower in green vegetables, fruit and dairy; and drinking alcohol, including beer, appear to increase your risk of developing fibroids.

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To determine the most appropriate treatment for your stroke, your emergency team needs to evaluate the type of stroke you're having and the areas of your brain affected by the stroke. They also need to rule out other possible causes of your symptoms, such as a brain tumor or a drug reaction. Your doctor may use several tests to determine your risk of stroke, including:
Physical examination. Your doctor will ask you or a family member what symptoms you've been having, when they started and what you were doing when they began. Your doctor then will evaluate whether these symptoms are still present.

Your doctor will want to know what medications you take and whether you have experienced any head injuries. You'll be asked about your personal and family history of heart disease, transient ischemic attack and stroke.

Your doctor will check your blood pressure and use a stethoscope to listen to your heart and to listen for a whooshing sound (bruit) over your neck (carotid) arteries, which may indicate atherosclerosis. Your doctor may also use an ophthalmoscope to check for signs of tiny cholesterol crystals or clots in the blood vessels at the back of your eyes.

Blood tests. You may have several blood tests, which tell your care team how fast your blood clots, whether your blood sugar is abnormally high or low, whether critical blood chemicals are out of balance, or whether you may have an infection. Managing your blood's clotting time and levels of sugar and other key chemicals will be part of your stroke care.
Computerized tomography (CT) scan. A CT scan uses a series of X-rays to create a detailed image of your brain. A CT scan can show a hemorrhage, tumor, stroke and other conditions. Doctors may inject a dye into your bloodstream to view your blood vessels in your neck and brain in greater detail (computerized tomography angiography). There are different types of CT scans that your doctor may use depending on your situation.
Magnetic resonance imaging (MRI). An MRI uses powerful radio waves and magnets to create a detailed view of your brain. An MRI can detect brain tissue damaged by an ischemic stroke and brain hemorrhages. Your doctor may inject a dye into a blood vessel to view the arteries and veins and highlight blood flow (magnetic resonance angiography, or magnetic resonance venography).
Carotid ultrasound. In this test, sound waves create detailed images of the inside of the carotid arteries in your neck. This test shows buildup of fatty deposits (plaques) and blood flow in your carotid arteries.
Cerebral angiogram. In this test, your doctor inserts a thin, flexible tube (catheter) through a small incision, usually in your groin, and guides it through your major arteries and into your carotid or vertebral artery. Then your doctor injects a dye into your blood vessels to make them visible under X-ray imaging. This procedure gives a detailed view of arteries in your brain and neck.
Echocardiogram. An echocardiogram uses sound waves to create detailed images of your heart. An echocardiogram can find a source of clots in your heart that may have traveled from your heart to your brain and caused your stroke.

You may have a transesophageal echocardiogram. In this test, your doctor inserts a flexible tube with a small device (transducer) attached into your throat and down into the tube that connects the back of your mouth to your stomach (esophagus). Because your esophagus is directly behind your heart, a transesophageal echocardiogram can create clear, detailed ultrasound images of your heart and any blood clots.

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Cancer refers to any one of a large number of diseases characterized by the development of abnormal cells that divide uncontrollably and have the ability to infiltrate and destroy normal body tissue. Cancer often has the ability to spread throughout your body.

Cancer is the second-leading cause of death in the United States. But survival rates are improving for many types of cancer, thanks to improvements in cancer screening and cancer treatment.

Symptom.

Signs and symptoms caused by cancer will vary depending on what part of the body is affected.

Some general signs and symptoms associated with, but not specific to, cancer, include:

Fatigue
Lump or area of thickening that can be felt under the skin
Weight changes, including unintended loss or gain
Skin changes, such as yellowing, darkening or redness of the skin, sores that won't heal, or changes to existing moles
Changes in bowel or bladder habits
Persistent cough or trouble breathing
Difficulty swallowing
Hoarseness
Persistent indigestion or discomfort after eating
Persistent, unexplained muscle or joint pain
Persistent, unexplained fevers or night sweats
Unexplained bleeding or bruising
When to see a doctor
Make an appointment with your doctor if you have any persistent signs or symptoms that concern you.

If you don't have any signs or symptoms, but are worried about your risk of cancer, discuss your concerns with your doctor. Ask about which cancer screening tests and procedures are appropriate for you.

Causes

Cancer is caused by changes (mutations) to the DNA within cells. The DNA inside a cell is packaged into a large number of individual genes, each of which contains a set of instructions telling the cell what functions to perform, as well as how to grow and divide. Errors in the instructions can cause the cell to stop its normal function and may allow a cell to become cancerous.

What do gene mutations do?

A gene mutation can instruct a healthy cell to:

Allow rapid growth. A gene mutation can tell a cell to grow and divide more rapidly. This creates many new cells that all have that same mutation.
Fail to stop uncontrolled cell growth. Normal cells know when to stop growing so that you have just the right number of each type of cell. Cancer cells lose the controls (tumor suppressor genes) that tell them when to stop growing. A mutation in a tumor suppressor gene allows cancer cells to continue growing and accumulating.
Make mistakes when repairing DNA errors. DNA repair genes look for errors in a cell's DNA and make corrections. A mutation in a DNA repair gene may mean that other errors aren't corrected, leading cells to become cancerous.
These mutations are the most common ones found in cancer. But many other gene mutations can contribute to causing cancer.

What causes gene mutations?
Gene mutations can occur for several reasons, for instance:

Gene mutations you're born with. You may be born with a genetic mutation that you inherited from your parents. This type of mutation accounts for a small percentage of cancers.
Gene mutations that occur after birth. Most gene mutations occur after you're born and aren't inherited. A number of forces can cause gene mutations, such as smoking, radiation, viruses, cancer-causing chemicals (carcinogens), obesity, hormones, chronic inflammation and a lack of exercise.
Gene mutations occur frequently during normal cell growth. However, cells contain a mechanism that recognizes when a mistake occurs and repairs the mistake. Occasionally, a mistake is missed. This could cause a cell to become cancerous.

How do gene mutations interact with each other?
The gene mutations you're born with and those that you acquire throughout your life work together to cause cancer.

For instance, if you've inherited a genetic mutation that predisposes you to cancer, that doesn't mean you're certain to get cancer. Instead, you may need one or more other gene mutations to cause cancer. Your inherited gene mutation could make you more likely than other people to develop cancer when exposed to a certain cancer-causing substance.

It's not clear just how many mutations must accumulate for cancer to form. It's likely that this varies among cancer types.

Risk factors

While doctors have an idea of what may increase your risk of cancer, the majority of cancers occur in people who don't have any known risk factors. Factors known to increase your risk of cancer include:

Your age

Cancer can take decades to develop. That's why most people diagnosed with cancer are 65 or older. While it's more common in older adults, cancer isn't exclusively an adult disease — cancer can be diagnosed at any age.

Your habits

Certain lifestyle choices are known to increase your risk of cancer. Smoking, drinking more than one alcoholic drink a day (for women of all ages and men older than age 65) or two drinks a day (for men age 65 and younger), excessive exposure to the sun or frequent blistering sunburns, being obese, and having unsafe sex can contribute to cancer.

You can change these habits to lower your risk of cancer — though some habits are easier to change than others.

Your family history

Only a small portion of cancers are due to an inherited condition. If cancer is common in your family, it's possible that mutations are being passed from one generation to the next. You might be a candidate for genetic testing to see whether you have inherited mutations that might increase your risk of certain cancers. Keep in mind that having an inherited genetic mutation doesn't necessarily mean you'll get cancer.

Your health conditions

Some chronic health conditions, such as ulcerative colitis, can markedly increase your risk of developing certain cancers. Talk to your doctor about your risk.

Your environment

The environment around you may contain harmful chemicals that can increase your risk of cancer. Even if you don't smoke, you might inhale secondhand smoke if you go where people are smoking or if you live with someone who smokes. Chemicals in your home or workplace, such as asbestos and benzene, also are associated with an increased risk of cancer.

Complications

Cancer and its treatment can cause several complications, including:

Pain. Pain can be caused by cancer or by cancer treatment, though not all cancer is painful. Medications and other approaches can effectively treat cancer-related pain.
Fatigue. Fatigue in people with cancer has many causes, but it can often be managed. Fatigue associated with chemotherapy or radiation therapy treatments is common, but it's usually temporary.
Difficulty breathing. Cancer or cancer treatment may cause a feeling of being short of breath. Treatments may bring relief.
Nausea. Certain cancers and cancer treatments can cause nausea. Your doctor can sometimes predict if your treatment is likely to cause nausea. Medications and other treatments may help you prevent or decrease nausea.
Diarrhea or constipation. Cancer and cancer treatment can affect your bowels and cause diarrhea or constipation.
Weight loss. Cancer and cancer treatment may cause weight loss. Cancer steals food from normal cells and deprives them of nutrients. This is often not affected by how many calories or what kind of food is eaten; it's difficult to treat. In most cases, using artificial nutrition through tubes into the stomach or vein does not help change the weight loss.
Chemical changes in your body. Cancer can upset the normal chemical balance in your body and increase your risk of serious complications. Signs and symptoms of chemical imbalances might include excessive thirst, frequent urination, constipation and confusion.
Brain and nervous system problems. Cancer can press on nearby nerves and cause pain and loss of function of one part of your body. Cancer that involves the brain can cause headaches and stroke-like signs and symptoms, such as weakness on one side of your body.
Unusual immune system reactions to cancer. In some cases the body's immune system may react to the presence of cancer by attacking healthy cells. Called paraneoplastic syndrome, these very rare reactions can lead to a variety of signs and symptoms, such as difficulty walking and seizures.
Cancer that spreads. As cancer advances, it may spread (metastasize) to other parts of the body. Where cancer spreads depends on the type of cancer.
Cancer that returns. Cancer survivors have a risk of cancer recurrence. Some cancers are more likely to recur than others. Ask your doctor about what you can do to reduce your risk of cancer recurrence. Your doctor may devise a follow-up care plan for you after treatment. This plan may include periodic scans and exams in the months and years after your treatment, to look for cancer recurrence.
Prevention
There's no certain way to prevent cancer. But doctors have identified several ways of reducing your cancer risk, such as:

Stop smoking. If you smoke, quit. If you don't smoke, don't start. Smoking is linked to several types of cancer — not just lung cancer. Stopping now will reduce your risk of cancer in the future.
Avoid excessive sun exposure. Harmful ultraviolet (UV) rays from the sun can increase your risk of skin cancer. Limit your sun exposure by staying in the shade, wearing protective clothing or applying sunscreen.
Eat a healthy diet. Choose a diet rich in fruits and vegetables. Select whole grains and lean proteins.
Exercise most days of the week. Regular exercise is linked to a lower risk of cancer. Aim for at least 30 minutes of exercise most days of the week. If you haven't been exercising regularly, start out slowly and work your way up to 30 minutes or longer.
Maintain a healthy weight. Being overweight or obese may increase your risk of cancer. Work to achieve and maintain a healthy weight through a combination of a healthy diet and regular exercise.
Drink alcohol in moderation, if you choose to drink. If you choose to drink alcohol, limit yourself to one drink a day if you're a woman of any age or a man older than age 65, or two drinks a day if you're a man 65 years old or younger.
Schedule cancer screening exams. Talk to your doctor about what types of cancer screening exams are best for you based on your risk factors.
Ask your doctor about immunizations. Certain viruses increase your risk of cancer. Immunizations may help prevent those viruses, including hepatitis B, which increases the risk of liver cancer, and human papillomavirus (HPV), which increases the risk of cervical cancer and other cancers. Ask your doctor whether immunization against these viruses is appropriate for you.
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What is a hormonal imbalance?

Hormones are your body’s chemical messengers. Produced in the endocrine glands, these powerful chemicals travel around your bloodstream telling tissues and organs what to do. They help control many of your body’s major processes, including metabolism and reproduction.

When you have a hormonal imbalance, you have too much or too little of a certain hormone. Even tiny changes can have serious effects throughout your whole body.

Think of hormones like a cake recipe. Too much or too little of any one ingredient affects the final product. While some hormone levels fluctuate throughout your lifetime and may just be the result of natural aging, other changes occur when your endocrine glands get the recipe wrong.
Symptoms of a hormonal imbalance.

Your hormones play an integral role in your overall health. Because of that, there’s a broad range of symptoms that could signal a hormonal imbalance. Your symptoms will depend on which hormones or glands aren’t working properly.

Common hormonal conditions affecting both men and women could cause any of the following symptoms:

fatigue

increased sensitivity to cold or heat
constipation or more frequent bowel movements
unexplained weight loss (sometimes sudden)
increased or decreased heart rate
muscle weakness
frequent urination
increased thirst
muscle aches, tenderness, and stiffness
pain, stiffness, or swelling in your joints
thinning hair or fine, brittle hair
increased hunger
depression
decreased sex drive
nervousness, anxiety, or irritability
blurred vision
a fatty hump between the shoulders
rounded face
purple or pink stretch marks
infertility
sweating

Causes of a hormonal imbalance

There are many possible causes for a hormonal imbalance. Causes differ depending on which hormones or glands are affected. Common causes of hormonal imbalance include:

underactive thyroid

overactive thyroid
hypogonadism
thyroiditis
hyperfunctioning thyroid nodules
tumors (benign or cancerous)
medications
adrenal insufficiency
pituitary tumor
injury or trauma
cancer treatments
diabetes
cushing syndrome
hormone therapy
eating disorders
stress
congenital adrenal hyperplasia
cancer treatments

Causes unique to women

Many causes of hormonal imbalance in women are related to reproductive hormones. Common causes include:

pregnancy
breastfeeding
primary ovarian insufficiency
menopause
PCOS
premature menopause
hormone drugs like birth control pills

Treatment options for a hormonal imbalance

Treatment for a hormonal imbalance will depend on what’s causing it.

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Weight Loss That Works! Obesity is a serious societal problem and has reached epidemic proportions posing a grave health challenge in the modern world. Obesity can be defined as having a body-mass index (BMI) of 30 or greater, whereas a BMI of between 25 and 29.9 is considered overweight. The World Health Organization (WHO) estimated in 2008 there were 1.4 billion overweight people in the world, including 500 million cases of obesity. More recent research studies by WHO show that 70% of Americans are now either obese or overweight.
These statistics are particularly worrisome. Having high BMI (overweight) or being obese contributes significantly to the development of several chronic conditions. They include insulin resistance, type 2 diabetes, hypertension, atherosclerosis, coronary heart disease, fat metabolism disorders, and inflammatory diseases of the gallbladder.
Therapies offered by modern medicine are not without their complications and do not always guarantee success in the form of permanent weight reduction.
(1) There are two main products that currently exist for managing obesity: One is a drug which works by reducing appetite leading to weight loss. When people take medications for weight loss there may be some measurable results, however, other unwanted side effects could result like damage to the stomach lining causing their bodies to lose the ability to absorb necessary nutrients. In addition, patients may develop diarrhea from using these drugs in the process of undergoing detoxification. Where some of the complications are mild, others could be severe enough to be debilitating or lead to death.
(2) In Traditional Chinese Medicine, obesity is a multi organ problem involving the spleen, kidney and liver. If the spleen and kidney are energy deficient the body won’t have enough energy to carry out its function. Invariably, water and liquids will be kept in the body resulting in obesity, this kind of water and liquid is called internal phlegm. The internal phlegm blocks circulation causing more problems. The liver is responsible for regulating the entire energy flow in the body; therefore stasis of liver energy will directly affect circulation as well. So to regulate the body’s energy and improve circulation, the spleen and kidney have to be restored to their initial energy levels then there can be weight reduction.
DetoXlim is a fat detoxifier designed for regulating liver energy, improving circulation and giving a great boost to the spleen and kidney. It addresses the root cause of obesity and makes it easier to keep the weight under control. Note, when used in combination with Magic Eastern Coffee, it produces better results at recovering from obesity quickly and with no side effects.
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