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Health › Re: Grant Or Loan To Do Sickle Cell Disease Research Here In Nigeria by kaima2015(op): 9:41pm On May 21, 2016

i can be able to fund the research myself if i get a job and am trusting GOD for that...am through with my academic year in my masters program and by GOD s grace came out tops in the faculty with a distinction but no help from the university either

Health › Re: Grant Or Loan To Do Sickle Cell Disease Research Here In Nigeria by kaima2015(op): 9:14pm On May 21, 2016

reyscrub:
Many might not understand your request and also many might think dat you are blabing.

The truth is dat many who are HBSS are daily crying of pain, panting of crisis and hoping for a talented messaih who shall one day discover a lasting cure and solution to this dreaded killer.

If you mean to thoroughly plung in the ocean of research for lasting solution, why not consult some agency especially research institutions in country to discourse to work with them and plead for financial support.

There are many synthetic and molecular drugs for treating dis ailment even dis most international effective nutrient drug called Dioscovite by Nigeria born Dr Agbai based in U.S.

Your own discovery can be a breaking through and prayer answering for many consigned ones.

Kindly source for fund carry out your research work

A disease with 180,000 deaths per year and with approximately 4 million sufferers in Nigeria alone is not to be taken lightly with.

Dear Nairalander, I have consulted several research institutes in Nigeria, they showed interest in the work but they insist that i buy the consumables for the research myself....they are only willing to assist with facilities and equipment

I also tried contacting several NGOs and even some Sickle Cell Foundations on the research but no response

I even went to the extent of trying to reach out to my state governor and some senators but no response

What are we trying to do here in simple terms?

Gene therapy for Sickle Cell Anemia Disease is still in its embryonic stage and also there is the fear of wrongful gene insertion into house keeping genes which can prove fatal

So the panacea may currently lie with what is called Fetal Hemoglobin Induction

Fetal Hemoglobin Induction in simple terms is trying to induce the production of the hemoglobin we all had as a fetus......which for people with HbSS...will make them not to fall sick and thus improve their clinical profile

For people with HbSS the genes responsible for the Fetal Hemoglobin (the gamma globin genes) begin to shut down after birth and thus the onset of crisis from about 6 months

So amelioration may lie in trying to switch on these genes back (upregulation) in order to improve the clinical profile of patients....thus currently there is a rush worldwide for pharmacologic agents that will be able to do this

Hydroxyurea is not that effective because it can only induce fetal hemoglobin to about 17% and we need about 32%

Dioscovite is basically KCN an antisickling agent

Health › Grant Or Loan To Do Sickle Cell Disease Research Here In Nigeria by kaima2015(op): 3:16pm On May 21, 2016*

Please Nairalanders, is there any way one can get funds in the form of grant or loan to do sickle cell disease research here in Nigeria?......the research is geared towards finding a better pharmacologic agent that is better than Hydroxyurea for fetal hemoglobin induction for the management of Sickle Cell Disease (hydroxyurea is cytotoxic and only effective in about 50% of cases)....we will be using also a plant named Hymenocardia acida (the catechins fraction) and we will be doing a cell culture from PBMCs isolated from peripheral blood that will lead to generation of Erythroid Progenitor Stem Cells (EPSCs) .....the total funds for the research will cost about 2000usd and we are looking for a WAY to go about it...thank you

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Politics › Is This The Current Situation? by kaima2015(op): 6:02pm On May 19, 2016

Nairalanders what do you say?

Jobs/Vacancies › Re: Spss Expert Urgently Needed In Abuja by kaima2015: 3:03pm On May 07, 2016

orbitame2011:
Good, you can send your details to

orbitame2011@gmail.com

details (cv) sent...thanks

Jobs/Vacancies › Re: Spss Expert Urgently Needed In Abuja by kaima2015: 6:34am On May 07, 2016

i can and i reside in abuja

Education › Re: What Is State/lga Certificate Of Origin? by kaima2015: 4:12am On May 02, 2016

go to your state's liason office in abuja and get it the same day...you will require at least 2k, two passport photographs, the name of your village chief/oba/emir etc...thats all

Education › Re: Federal Scholarship Board Of Nigeria 2016 Scholarship Awards by kaima2015: 7:41am On Apr 30, 2016

same thing here.....went to the fsb, abuja yesterday and they have not heard anything about the scholarship!....they asked me whether i was sure it was on their website!.....it is my opinion that the program was initiated from the federal ministry of education, abuja but it has not yet filtered down to its subsidiary, the fsb.....they advised i should wait a bit (a week or two)

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Education › Re: Federal Scholarship Board Of Nigeria 2016 Scholarship Awards by kaima2015: 2:51pm On Apr 27, 2016

will go to federal scholarship board.....if i am successful in getting a copy of the form.....will paste here

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Education › Re: Federal Scholarship Board Of Nigeria 2016 Scholarship Awards by kaima2015: 8:17am On Apr 26, 2016

IrradiatoR:
Not at all. . .

We all know how things like this go in Nigeria, when you get to the place of issuance, you start hearing excuses like:

I. we don't have the forms yet,
ii. the Secretary is not on sit ,
iii. the Secretary has gone out to eat bla bla bla. . .

and some may forgetfully/deliberately keep your completed forms somewhere such that it doesn't get processed with others. . .

An online application would have been better, where the forms are filled and submitted online, the Federal Scholarship Board only needs to contact the Academic and Records Unit of each institution to forward names of students with CGPA of 4 points and above for further necessary action.

Has anyone obtained a copy of the form ? Could you share please.....it is the same form everywhere (so i heard)....having obtained the form we could still follow the departmental process because it requires an endorsement by your departmental HOD

Education › Re: Federal Scholarship Board Of Nigeria 2016 Scholarship Awards by kaima2015: 8:16am On Apr 26, 2016

IrradiatoR:
Not at all. . .

We all know how things like this go in Nigeria, when you get to the place of issuance, you start hearing excuses like:

I. we don't have the forms yet,
ii. the Secretary is not on sit ,
iii. the Secretary has gone out to eat bla bla bla. . .

and some may forgetfully/deliberately keep your completed forms somewhere such that it doesn't get processed with others

An online application would have been better, where the forms are filled and submitted online, the Federal Scholarship Board only needs to contact the Academic and Records Unit of each institution to forward names of students with CGPA of 4 points and above for further necessary action.

Career › Re: All Job Interview Questions/answers Covered - Get The Free Ebook by kaima2015: 8:34am On Apr 24, 2016

please forward to andico34@gmail.com......thanks

Jobs/Vacancies › Re: Job Seekers: What Course Did You Study by kaima2015: 3:17pm On Apr 11, 2016

M.S.c Biotechnology

Education › Re: . by kaima2015: 6:31am On Apr 02, 2016

ahmadu bello, bayero and abeokuta...the only 3 offering msc biotechnology

Properties › Re: Two Rooms Mini Flat And Self-contain Fenced @ Ogudu, Lagos by kaima2015: 11:15pm On Mar 24, 2016

wip7:
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3. Water and mini Gen available within the compound
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1. One bedroom self-contain
2. Properly Tiled and fenced compound
3. Water and mini Gen available within the compound
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dear wip7 i sent you an email on education from andico34@gmail.com. thank you very much

Science/Technology › Possible Breakthrough On HIV From Israel! by kaima2015(op): 6:54am On Jan 11, 2016

Possible Breakthrough on HIV from Israel...Human Clinical Trials to start within 3 months!

http://www.ynetnews.com/articles/0,7340,L-4750903,00.html

Education › Re: Grant Or Loan To Do Research Here In Nigeria by kaima2015(op): 10:53am On Oct 29, 2015

Raymondenyi:
Check elsewhere, not in Nigeria

thanks for the hint...quite sad....for a disease affecting 5 million nigerians

Politics › Re: Good News...sickle Cell Cur Found... by kaima2015: 8:22am On Oct 29, 2015

Raymondenyi:
really nothing new here; stem cell transplant has been the cure for sickle cell disease and many blood dyscrasias from time immemorial, though the success rate is not 100%... the only thing i see here is just; the procedure of SCT was made more easier than it used to be....

This is really no Eureka moment per say.

seconded, as rightly said by Raymondenyi ,this is no new discovery because the major drawback still remains- "sibling donors" etc. the cure to sickle cell anemia(sca) could come through using gene delivery therapy using IPSCs for instance, but we have to overcome the physiological hurdles associated with vector design and delivery. question is "why are introduced corrected genes readily taken up in murine models than in human models?'' Amelioration still remains the only feasible option for now-drug repositioning: introducing an already FDA approved drug that will switch on the gamma globin genes that are responsible for the production of fetal hemoglobin (which will bring about a greater clinical wellbeing) for SCA patients, hydoxyurea only achieves 17%! we need about 32% to achieve this, this is what we are working on in our research for we are looking for funding. nigeria is not research inclined. i may be wrong

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Education › Re: Grant Or Loan To Do Research Here In Nigeria by kaima2015(op): 9:17am On Oct 27, 2015

Please Nairalanders is there any NGO or research body that can help with this?....Thank you

Politics › Re: Jonathan's Daughter, Faith Sakwe Welcomes Baby Girl by kaima2015: 7:01pm On Sep 23, 2015

look!...the pikin resemble PEJ well well grin

Health › Two Headed Baby! (viewers' Discretion) by kaima2015(op): 4:35pm On Sep 16, 2015

This was recently sent in by a friend whose mum (a matron and midwife) delivered a two headed baby in the local cottage hospital in Jigawa State. It is the first time I am seeing such in Nigeria and felt I should share....Please pardon the pix

Pets › Re: What Is This Life Turning Into!!!(photo) by kaima2015: 12:15pm On Sep 16, 2015

yemi2plus:
I think otherwise. The dog looks so sick, I doubt if it has eaten since the last 7 days.

LWKMD!.....the female dog is thin because it just had a litter (it is a lactating mother)....and thats why the kitten is able to get milk from her...they normally lose much weight as a result if not well fed as a result

Adverts › Trading American Stocks Online! by kaima2015(op): 10:15pm On Sep 15, 2015

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Education › Grant Or Loan To Do Research Here In Nigeria by kaima2015(op): 4:23pm On Sep 07, 2015

Please Nairalanders, is there any way one can get funds in the form of grant or loan to do research here in Nigeria?......the research is geared towards finding a better pharmacologic agent that is better than Hydroxyurea for the management of Sickle Cell Disease (hydroxyurea is cytotoxic and only effective in about 50% of cases)....the total funds for the research will cost about 2 million naira and we are looking for a WAY to go about it...thank you

Christianity Etc › Re: My Pastor Justified Taking Another Wife With Scripture, Is He Right? by kaima2015: 10:49am On Sep 06, 2015

Debeloved87:
My pastor's marriage crashed last year, thou the marriage produced children and the parting seems unreconcilable even thou i think it fell on domestic issues and also the fact that the wife doesn't really flow with the pastoral call of the husband as her pastor husband wish her to.

Recently the man of God was talking about it and he said that he will take a new wife very soon anytime he is ready, and he ask us whether its scriptural but we just giggled and he told us that it is scriptural that we should open the book of 1 corinthians 7:14-15 "for the unbelieving husband is sanctified by the wife and the unbelieving wife is sanctified by the husband, else where your children unclean but now are they holy; but if the unbelieving depart,let him depart, a brother or a sister is not under bondage in such cases:but God has called us to peace...

This actually was a little bit confusing to me, since the wife in question wasn't an unbeliever... Is my pastor right with his assertions?

am not a pastor.....but let me give a contribution.....the BIBLE should not be read in the literal sense but the actual greek/hebrew meanings of the word should be translated and then the actual meaning deciphered in the context......an unbelieving wife/husband....does not fully mean he/she must be born again but also includes unity in purpose i.e oneness in vision or divine purpose
so.....the pastor is partly correct...how? if the "unbelieving wife" ...files "for a divorce"...or "leaves" the husband (sole action must be hers and hers alone)....then the husband is no longer bound to that marriage...(he is still bound before GOD !)....but he is free to remarry ...and not the other way round......i can clarify if there are questions ...thanks

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