₦airaland Forum

Lala and snake,

Why not travel and explore other countries to see the reason why people migrate for a better life?

Jaytecq:
Good for them..... build in your country... them go say No .... Invest in your country... them go say No

Anyone in dallas Texas

Nigerians will carry americas wahala on their head like gala.

To onitsha and aba

clems88:
I travel twice every month its really fun

In this recession....Na wa ooo

You came to check if your uncle is among ??

SOFTENGR:
I came to check names, but ...disappointed

Nothing to comment, just wanna make FTC, been a while.

Car that have been seeing since last year here in dallas.

Anyone in Ruston Louisiana ?

Let the fight start from you, where is your cutlass?

VivyGift: Sometimes it annoys me when I see some serious issues taken as a joke, instead of us to put our heads together probably to fight against it or find a solution to it.

Wonders shall never end, i wonder who is going to Zambia, what are they doing there?

An Iranian passenger plane carrying a least 117 people crashed in the snowy mountains of western Iran near Khorramabad, officials said.

No details on the number injured or killed were immediately available, nor was there information on the cause of the crash.

Reza Jaafarzadeh, a spokesman for the Civil Aviation Organisation of Iran, said that at least 117 passenger and crew were aboard the plane, flight No. 956.

"Several search teams have been dispatched to the region," Jaafarzadeh said.

An official at the Khorramabad governor's office said searchers had identified the mountainous, snow-covered area of the crash.

The Tu-154, a Russian-made Tupolev operated by state-owned Iran Air Tours, left Tehran at 7.30am headed for Khorramabad, about 230 miles south west of the capital, state radio reported.

Residents of a village near Khorramabad heard a "big explosion" and fire after the Tupolev went down, the radio said.

Iran Air Tours in recent years has leased mostly Russian-made Tupolev planes with Russian crew.

A Russian-built aircraft, a YAK-40 operated by the private Faraz Qeshm Airlines crashed in north eastern Iran in May, killing the transport minister and about 30 other passengers including seven lawmakers. They were on their way to Gorgan, near the Caspian Sea, to inaugurate that city's airport.

Iran also has an aging fleet of U.S.-made Boeings purchased before the 1979 Islamic revolution. The United States has refused to provide spare parts for Boeing planes as part of its wide-ranging economic sanctions against Iran.

Iran has said the U.S. stance on spare parts endangered the lives of innocent passengers.

In recent years, Iran has purchased a small number of Airbus passenger planes.

On July 3, a Tu-154 slammed into a Siberian meadow, killing all 145 people aboard. That crash was the 20th involving a Tu-154 since it entered service in the early 1970s. With some 1,000 planes built, it is the most widely used jetliner in Russia and is used in many other countries.

In February 1993 a Russian-made Tu-134 on lease to Iran collided with a military plane near Tehran, killing all 132 people on board.


http://www.dailymail.co.uk/news/article-99911/Passenger-plane-crashes-Iran.html

Edward snowden prefer to stay where there is snow.

Na lie na Nigeria be number 1, na Ebola cuz am wey dem no put us.

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The one came to nigeria how did he got there?

I have been wondering for the past few days how i can be able to prevent myself inside the plane just incase there is an ebola victim boarding the jetliner as well. I need matured comment pls.

Chinese toys assembled in nigeria.......

As if from a science fiction movie, the Ebola virus is one of the most lethal viruses known to man. The haste with which it dispatches its victims is truly gruesome! Ebola was first identified in Africa in1976, and can be caused by any four of the five Ebola viruses: Bundibugyo virus, Ebola virus, Sudan virus, and Taï forest virus. The fifth virus, Reston virus is not thought to be disease causing for humans. Ebola is a member of the family Filoviridae in the order Mononegavirales. EVD has a case fatality rate of 90%. Infections of the virus cause a rapidly fatal haemorrhagic fever. Humans become infected by contact with bodily fluids from an infected person or objects that have been contaminated. The virus can also be contracted from infected animals. The reservoir of Ebola is still unknown, but scientists believe fruit bats are the most likely hosts.

Incubation spans two to twenty-one days and symptoms include: weakness, fever, aches, diarrhoea, vomiting and stomach pain, throat soreness, difficulty breathing, or swallowing and bleeding. Within days the virus causes a condition known as disseminated intravascular coagulation, which is marked by both blood clots and haemorrhaging. Patients exhibit symptoms of spontaneous bleeding from body orifices and any breaks in the skin, including injection sites. The virus attacks the gastrointestinal tract, skin, and internal organs. Death is brought on by haemorrhaging, shock, or renal failure and occurs within 8 to 17 days. No FDA approved therapy for Ebola virus exists, though the FDA is currently fast tracking a RNA interference therapy specific to the Ebola virus being developed by Tekmira Pharmaceuticals.


So what does the Ebola virus look like? In fact, it has a quite menacing look. To start with, it has a threadlike structure, which is characteristic of all filoviruses. The virons are tubular and have a diameter around 80 nm. To increase its menacing appearance, lipid bilayer anchors called glycoproteins, project 10 nm spikes from the viral envelope. They’re generally somewhere between 800 nm and 1000nm long. The nucleocapsid in the center of the viron is made of a RNA wound helically with the proteins NP, VP35, VP30, and last but not least L. The viral proteins VP40 and VP24 are found in the viral tegument or the area between the envelope and nucleocapsid.


Each viron of Ebola virus has a single stranded, negative sense RNA linear genome. It’s between 18,959 and 18,961 nucleotides in length. One frightening aspect of the virus is that replication of the virus can occur with only 427 nucleotides from the 3’ end and 731 nucleotides from the 5’ end. The virus codes for seven structural proteins and one non-structural protein. Having a negative sense polarity, the virus’ RNA structure begins in the 3’ position and ends in the 5’ position. Following the 3’ position is a non-transcribed region known as the leader. Next, a nucleoprotein of 739 amino acids that plays a central role in the virus’ replication. Then comes a protein known as VP35, which is responsible for binding a double stranded RNA and inhibiting the host cells alpha/beta interferon. After this comes the VP40 protein, which uses the COPII transport system for intracellular transport. Then comes the sGP that serves as a structural protein in the virus and then the VP30 protein, which is a RNA binding protein. Next comes the VP24 protein that the virus uses to prevent Heterogeneous ribonucleoprotien particles C1/C2 binding to Karyopherin Alpha-1 and partially alter its nuclear import. This is followed by an L protein which caps and Polyadenylates mRNA’s. Next comes a non-transcribed trailer, and finally 3’. What’s interesting about the leader and trailer is that they carry signals which control transcription, replication, and package the viral genomes into new virons.

As I mentioned earlier the virus’s lipid bilayer anchors glycoproteins, which project 10 nm spikes. What I didn’t mention was that these spikes mediate the entry of the virus into the cell. The spikes attach viral particles to the cell surface. The viral particles adhere to lectin proteins and are taken up and transported to endosomes which contain host proteins cathepsin B and Niemann Pick C1 (NPC1) and catalyze fusion between viral and the endosomes membranes. In a study published in Nature by the MIT’s Whitehead Institute for Biomedical Research, it was found that for the Ebola virus to enter it required the cholesterol transporter Niemann-Pick C1 (NPC1). In the study, cells with mutated NPC1 proteins were exposed to the Ebola virus and something very, very interesting happened: The cells survived and appeared to be immune to the virus. This is interesting for that fact that this particular mutation causes a naturally occurring genetic disease (unfortunately terminal). So technically these people with Niemann-Pick disease type C, would be immune to some of the earth’s most deadly viruses. Also significant, it shows that the Ebola uses the NPC1 protein to enter the cell. The same immunity was found with Ebola’s filovirus cousin the Marburg virus. So the NPC1 protein is essential for the entry of filoviruses and acts as a receptor for the virus that mediates the infection by binding directly to the viral envelope glycoprotein.


The Ebola virus, like all viruses, must reproduce its components and assemble itself within cells, by hijacking cellular machinery to reproduce its infectious virons. So let’s go over the replication process and then look further into the proteins that affect this. The virus begins by attaching itself to the host’s receptor through its glycoprotein spike (peplomer) Then, it goes through the process of macropinocytososis forming a pocket around the virus when it enters the host. The viral membrane then fuses with the vesicle membrane, and the nucleocapsid is released into the host cells cytoplasm. Then the negative-sense genomic ssRNA, which is enclosed in a protein shell, is used as a template for synthesis (3’-5’) of the polyadenylated messenger RNA. The cellular machinery begins translating mRNA into viral proteins. Viral proteins are processed, and the glycoprotein precursor is cleaved to heavily glycosylated GP1 and GP2. The GP1 and GP2 molecules assemble first into heterodimers, and then into trimmers to give the surface glycoprotein spikes. The secreted glycoprotein precursor is cleaved to sGP and delta peptide both of which are released from the cell. As the number of viral proteins in the cell rise, a switch happens. Things go from translation to replication… The negative sense genomic RNA is used as a template and a extra single stranded RNA is synthesized then used as a template for the synthesis of new genomic ssRNA which is rapidly encapsidated. Then things start to get really bad for the cell: Newly formed nucleocapsids and envelope proteins associate at the host cell’s plasma membrane. Budding occurs, and the cell is destroyed.

This is no news, man must chop anyhow anyhow.

U take picture, e no fine, u come dey claim say 'beauty is from within' .... Why u no take X-ray na?

You will remove some girl's bra and their boobs will fall down like the wall of Jericho...smh

ur boyfriend buys you Iphone5s for Valentines day and you bought him 2 white handkerchiefs, a white singlet and boxers.Is he an 'atilogwu' dancer?

ur boyfriend buys you Bold5 for Valentines day and you buy him 2 white handkerchiefs, a white singlet and boxers.Is he an 'atilogwu' dancer?

Researchers have published a study that shows college students combining caffeinated drinks with booze don’t realize how intoxicated they really are.

In a study published in the Journal of Adolescent Health, researchers at the Institute for Social Research at the University of Michigan have concluded that mixing alcohol and energy drinks poses a serious public health risk, especially among college students. "We found that college students tended to drink more heavily, become more intoxicated, and have more negative drinking consequences on days they used both energy drinks and alcohol, compared to days they only used alcohol," said Megan Patrick, a research assistant professor and co-author of the study.

According to the study, students who either drank alcohol and energy drinks on the same day or who combined the two at the same time wound up spending more time drinking – thus consuming more alcohol – than they would have without the caffeinated drinks. The result of spending more hours drinking raised users' blood alcohol levels to higher peaks. But because of the stimulant effects of the energy drinks, the users reported that they felt less drunk than they actually were. "This can have serious potential health impacts, for example if people don't realize how intoxicated they actually are and decide to drive home," Patrick said.

But a similar study conducted by the Department of Community Health at the Boston University School of Public Health found that it wasn’t necessarily the combination of alcohol and caffeine that posed a risk, but the profile of the drinkers themselves that led to negative consequences. "It appears that the consumption of caffeinated alcoholic beverages has a direct effect on increasing risk by masking intoxication and making it easier for youth to consume more alcohol,” said Dr. Michael Siegel, one of the authors of the Boston University’s study. “It also appears that consumption of alcohol with caffeine may itself be a marker for youth who engage in riskier behavior.”



More comments on the link source.
http://www.thefix.com/content/alcohol-and-energy-drinks-dangerous-combo-study-says?utm_source=disqus&utm_medium=Referral%20CPC&utm_content=Title%20of%20The%20Article&utm_campaign=The%20Fix%20CPC

Aruba what are u saying ?

Tyche: There's a natural mystic
Blowing through the air
If you listen carefully now you will hear
This could be the first trumpet
Might as well be the last
Many more will have to suffer
Many more will have to die
Don't ask me why
Things are not the way they used to be
I won't tell no lie
One and all got to face reality now


Though I try to find the answer
To all the questions they ask
Though I know it's impossible
To go living through the past
Don't tell no lie
There's a natural mystic
Blowing through the air
Can't keep them down
If you listen carefully now you will hear
Such a natural mystic
Blowing through the air



This could be the first trumpet
Might as well be the last
Many more will have to suffer
Many more will have to die
Don't ask me why
There's a natural mystic
Blowing through the air
I won't tell no lie
If you listen carefully now, you will hear
There's a natural mystic
Blowing through the air

(CNN) -- Forty-seven people were killed and 11 were injured in Wednesday's plane crash on one of Taiwan's Penghu Islands, Taiwan's Central News Agency reported. CNA cited Taiwanese Transportation Minister Yeh Kuang-shih.

The crash of the twin-engine turboprop plane happened outside Magong Airport at about 7 p.m., CNA reported earlier.

CNN affiliate ETTV is reporting that the plane crashed into a residential building.

The cause of the crash wasn't immediately known.

Some media reports said the plane was making a crash landing prompted by strong winds from Typhoon Matmo, which hit Taiwan early Wednesday, according to CNA.

The plane, an ATR 72, had taken off from Kaohsiung, Taiwan, CNA reported. The Penghu Islands are off the main Taiwanese island's west coast.

There were 54 passengers and four crew aboard the flight, said Jean Shen, the director-general of the Civil Aeronautics Administration, at a press conference.

http://edition.cnn.com/2014/07/23/world/asia/taiwan-plane-crash/index.html