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Nairaland Forum / Science/Technology / Totally Blind Mice Get Sight Back (6241 Views)
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Totally Blind Mice Get Sight Back by mkmyers45(m): 8:12pm On Jan 06, 2013 |
Totally blind mice have had their sight restored by injections of light-sensing cells into the eye, UK researchers report. The team in Oxford said their studies closely resemble the treatments that would be needed in people with degenerative eye disease. Similar results have already been achieved with night-blind mice. Experts said the field was advancing rapidly, but there were still questions about the quality of vision restored. Patients with retinitis pigmentosa gradually lose light-sensing cells from the retina and can become blind. It's the first proof that you can take a completely blind mouse, put the cells in and reconstruct the entire light-sensitive layer” Prof Robert MacLaren University of Oxford The research team, at the University of Oxford, used mice with a complete lack of light-sensing photoreceptor cells in their retinas. The mice were unable to tell the difference between light and dark. Reconstruction They injected "precursor" cells which will develop into the building blocks of a retina once inside the eye. Two weeks after the injections a retina had formed, according to the findings presented in the Proceedings of the National Academy of Sciences journal. Prof Robert MacLaren said: "We have recreated the whole structure, basically it's the first proof that you can take a completely blind mouse, put the cells in and reconstruct the entire light-sensitive layer." Previous studies have achieved similar results with mice that had a partially degenerated retina. Prof MacLaren said this was like "restoring a whole computer screen rather than repairing individual pixels". The mice were tested to see if they fled being in a bright area, if their pupils constricted in response to light and had their brain scanned to see if visual information was being processed by the mind. Vision Prof Pete Coffee, from the Institute of Ophthalmology at University College London, said the findings were important as they looked at the "most clinically relevant and severe case" of blindness. Continue reading the main story “Start Quote This is probably what you would need to do to restore sight in a patient that has lost their vision” Prof Pete Coffee University College London "This is probably what you would need to do to restore sight in a patient that has lost their vision," he said. However, he said this and similar studies needed to show how good the recovered vision was as brain scans and tests of light sensitivity were not enough. He said: "Can they tell the difference between a nasty animal and something to eat?" Prof Robin Ali published research in the journal Nature showing that transplanting cells could restore vision in night-blind mice and then showed the same technique worked in a range of mice with degenerated retinas. He said: "These papers demonstrate that it is possible to transplant photoreceptor cells into a range of mice even with a severe level of degeneration. "I think it's great that another group is showing the utility of photoreceptor transplantation." Researchers are already trialling human embryonic stem cells, at Moorfields Eye Hospital, in patients with Stargardt's disease. Early results suggest the technique is safe but reliable results will take several years. Retinal chips or bionic eyes are also being trailed in patients with retinitis pigmentosa. http://www.bbc.co.uk/news/health-20898935 |
Re: Totally Blind Mice Get Sight Back by Afam4eva(m): 8:18pm On Jan 06, 2013 |
Can this work on humans? If it can, then this will be a great medical breakthrough. |
Re: Totally Blind Mice Get Sight Back by Nobody: 8:43pm On Jan 06, 2013 |
afam4eva: Can this work on humans? If it can, then this will be a great medical breakthrough.Why wouldn't it? They only tested that procedure on the mouse and it worked. |
Re: Totally Blind Mice Get Sight Back by Nobody: 8:44pm On Jan 06, 2013 |
Great news... Stevie Wonder will be smiling.. one less miracle 2 Likes |
Re: Totally Blind Mice Get Sight Back by Nobody: 8:48pm On Jan 06, 2013 |
. Taken . |
Re: Totally Blind Mice Get Sight Back by pictures: 10:32pm On Jan 06, 2013 |
one day , we go just wake up see say oyibo don commot for this earth and we still dey count 3000 megawatts of light. 12 Likes |
Re: Totally Blind Mice Get Sight Back by mimiabayomi: 4:47am On Jan 07, 2013 |
Re: Totally Blind Mice Get Sight Back by lafuria1(m): 1:51pm On Jan 07, 2013 |
so the three blind mice have finally recovered their sight, great news. waiting for it to work on humans, we humans have more complex system than the mice, nice development though |
Re: Totally Blind Mice Get Sight Back by iamswizz(m): 1:53pm On Jan 07, 2013 |
Hope sey the mice don give their testimony |
Re: Totally Blind Mice Get Sight Back by frankie121(m): 1:56pm On Jan 07, 2013 |
pictures: one day , we go just wake up see say oyibo don commot I find ur comment very interesting. yes! the way those people are going, it ll happen soon. can u imagine the extent and level they are, we dey here thinking we are great. shame on our vision less so called leaders. |
Re: Totally Blind Mice Get Sight Back by Lobolintin(m): 2:15pm On Jan 07, 2013 |
ADVERT PLACEMENT THATS GOOOD IT MEANS THE WORLD REALY PROGRESSING |
Re: Totally Blind Mice Get Sight Back by simongonner: 2:18pm On Jan 07, 2013 |
na lie,na T.B JOSHUA HEAL THEM |
Re: Totally Blind Mice Get Sight Back by Andrew3(m): 2:18pm On Jan 07, 2013 |
Time to open a church and name it "Church of mircales int. company limited" bring in alot of the injection and plant in the seats. |
Re: Totally Blind Mice Get Sight Back by bunchyproject(m): 2:30pm On Jan 07, 2013 |
Re: Totally Blind Mice Get Sight Back by iammodel(m): 2:35pm On Jan 07, 2013 |
Yeah! Biotechnology using stem cells. Nice one! |
Re: Totally Blind Mice Get Sight Back by kenny987(f): 2:39pm On Jan 07, 2013 |
This procedure shld be carried out on our leaders so they can have some vision! By the time their eyes are punctured a time or two...we should get results! 3 Likes |
Re: Totally Blind Mice Get Sight Back by buchai: 3:12pm On Jan 07, 2013 |
I should say that research is the best way to advance in this modern days of technology. We sleep over everything while those with good intension wakesup with better results. |
Re: Totally Blind Mice Get Sight Back by Davijunson: 3:27pm On Jan 07, 2013 |
kenny987: This procedure shld be carried out on our leaders so they can have some vision! By the time their eyes are punctured a time or two...we should get results!LMAO......true talk. |
Re: Totally Blind Mice Get Sight Back by Nobody: 3:58pm On Jan 07, 2013 |
kenny987: This procedure shld be carried out on our leaders so they can have some vision! By the time their eyes are punctured a time or two...we should get results!some nairalanders need it too! |
Re: Totally Blind Mice Get Sight Back by cold(m): 5:17pm On Jan 07, 2013 |
Meanwhile Nigerians still have their hands clasped tightly in fervent prayers. Whilst other countries are engaging in research & development to make the world a better place.It's a sorry state of affairs 1 Like |
Re: Totally Blind Mice Get Sight Back by Onyenna(m): 6:43pm On Jan 07, 2013 |
Great news!.... |
Re: Totally Blind Mice Get Sight Back by blackbeau1(f): 9:38pm On Jan 07, 2013 |
pictures: one day , we go just wake up see say oyibo don commotlol |
Re: Totally Blind Mice Get Sight Back by Nobody: 1:57am On Jan 08, 2013 |
cold: Meanwhile Nigerians still have their hands clasped tightly in fervent prayers. Whilst other countries are engaging in research & development to make the world a better place.It's a sorry state of affairs the irony is that many of the scientists involved in such discovery are probably active christians who begin their day with their hands tightly clasped in fervent prayer. |
Re: Totally Blind Mice Get Sight Back by daryoor(m): 7:53am On Jan 08, 2013 |
all those beggers will soon be out of business. Make d injection no cost sha |
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